{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T08:16:21Z","timestamp":1759565781123},"reference-count":49,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2008,11,4]],"date-time":"2008-11-04T00:00:00Z","timestamp":1225756800000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2008,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>BACKGROUND:<\/jats:bold>Although studies have examined the prevalence of spina bifida (SB) among births, little is known about the SB prevalence among children and adolescents. We estimated the prevalence of SB among children and adolescents in metropolitan Atlanta.<jats:bold>METHODS:<\/jats:bold>This study used data from a population\u2010based registry of birth defects, with information on children with SB (cases) born in five Atlanta counties from 1979\u20132002. The population at risk was derived from United States Census data and variations in SB prevalence were examined by race\/ethnicity, sex, lesion level, age group under 20 years, 4\u2010year birth cohort, and time period using Poisson regression.<jats:bold>RESULTS:<\/jats:bold>From 1979 to 2002, SB birth prevalence decreased from 6.3 to 3.2 per 10,000 live births (<jats:italic>p<\/jats:italic>&lt; 0.001) and SB prevalence within each age group also declined. In 2002, there were 211 children 0\u201319 years old surviving with SB in Atlanta (2.4 per 10,000 children 0\u201319 years old); prevalence of SB was higher among non\u2010Hispanic whites and among children with lumbosacral lesion but did not vary by sex. With the exception of the most recent birth cohort (1998\u20132002), within each 4\u2010year birth cohort, the prevalence of SB was generally higher among non\u2010Hispanic whites than among non\u2010Hispanic blacks.<jats:bold>CONCLUSIONS:<\/jats:bold>This study provides minimum prevalence estimates among children and adolescents with SB in metropolitan Atlanta, and identifies race\/ethnic disparities in such prevalence estimates. This information could be useful for assessing the specialized health care needs for children with SB and the possible reasons for the racial\/ethnic variation in prevalence of SB. Birth Defects Research (Part A), 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/bdra.20530","type":"journal-article","created":{"date-parts":[[2008,11,5]],"date-time":"2008-11-05T14:48:59Z","timestamp":1225896539000},"page":"748-754","source":"Crossref","is-referenced-by-count":8,"title":["Prevalence of spina bifida among children and adolescents in metropolitan Atlanta"],"prefix":"10.1002","volume":"82","author":[{"given":"Mikyong","family":"Shin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilah M.","family":"Besser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adolfo","family":"Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,11,4]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"518","article-title":"Survival of infants with spina bifida\u2014Atlanta, 1972\u20131979","volume":"139","author":"Adams MM","year":"1985","journal-title":"Am J Dis Child"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20447"},{"key":"e_1_2_6_4_1","first-page":"225","article-title":"Spina bifida and hydrocephalus: a population study over a 35\u2010year period","volume":"44","author":"Bamforth SJ","year":"1989","journal-title":"Am J Hum Genet"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20404"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.04.018"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199911113412006"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20468"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1993.tb121690.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000056005"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.330.7491.574"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.10111"},{"key":"e_1_2_6_13_1","first-page":"1","article-title":"Surveillance for anencephaly and spina bifida and the impact of prenatal diagnosis\u2014United States, 1985\u20131994","volume":"44","author":"Cragan JD","year":"1995","journal-title":"MMWR CDC Surveill Summ"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2004.12.007"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1093\/oso\/9780192618849.003.0006","volume-title":"Secular trends. 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