{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:22:54Z","timestamp":1791904974866,"version":"4.3.4"},"reference-count":36,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2010,8,12]],"date-time":"2010-08-12T00:00:00Z","timestamp":1281571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND:<\/jats:title><jats:p>Renal agenesis and dysgenesis are potentially lethal congenital malformations affecting 2 to 5 infants per 10,000 live births annually in the United States. The low prevalence of these malformations has complicated understanding of potential risk factors. Maternal diabetes (type 1, type 2, and gestational) has been evaluated extensively as a risk factor for other congenital malformations, but only a limited number of studies have assessed the association between diabetes and renal agenesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>We conducted a population\u2010based case\u2010control study of deliveries after 20 weeks gestation in Texas Health Service Region 6 (Houston\/Galveston area) from January 1, 2000 to December 31, 2002. Cases of renal agenesis\/dysgenesis (n = 89) were ascertained from the Texas Birth Defects Registry. Cumulative incidence sampling was used to randomly select, from birth and fetal death records, 356 controls frequency matched to cases by delivery year and vital status. Maternal diabetes and other covariates were collected from vital records.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>The odds of renal agenesis\/dysgenesis were 3.1 (95% confidence interval [CI], 1.1\u20139.3) times greater among deliveries of mothers with diabetes compared to deliveries of mothers without diabetes, controlling for matching factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Our results are consistent with prior, but limited, research identifying diabetes as a risk factor for renal agenesis\/dysgenesis. While these data did not differentiate diabetes diagnoses by type, the results suggest that maternal diabetes may be associated with renal malformations. Further study is warranted. Birth Defects Research (Part A), 2010. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdra.20702","type":"journal-article","created":{"date-parts":[[2010,8,13]],"date-time":"2010-08-13T00:31:20Z","timestamp":1281659480000},"page":"722-727","source":"Crossref","is-referenced-by-count":40,"title":["Maternal diabetes and renal agenesis\/dysgenesis"],"prefix":"10.1002","volume":"88","author":[{"given":"Erin M.","family":"Davis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer D.","family":"Peck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Wild","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Langlois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,8,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443619750114022"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.48.11.2240"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000147122.97061.bb"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-4520.2010.00275.x"},{"key":"e_1_2_5_6_1","first-page":"869","article-title":"The validity of information on \u201crace\u201d and \u201cHispanic ethnicity\u201d in California birth certificate data","volume":"35","author":"Baumeister L","year":"2000","journal-title":"Health Serv Res"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.85.1.1"},{"key":"e_1_2_5_8_1","first-page":"679","article-title":"Renal agenesis surveillance\u2010\u2010United States","volume":"37","author":"Centers for Disease Control (CDC)","year":"1988","journal-title":"MMWR Morb Wkly Rep"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.06.028"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2613.2008.00593.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1900\/RDS.2006.3.134"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-008-0390-9"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-004-1337-3"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.11.017"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64982-8"},{"key":"e_1_2_5_16_1","article-title":"Agreement between self\u2010report and birth certificate for gestational diabetes mellitus: New York State PRAMS","author":"Hosler AS","year":"2009","journal-title":"Matern Child Health J"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.12.2819"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119066"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-005-1888-7"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2004.044305"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199505000-00016"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420250316"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.99.4.e11"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-200011000-00013"},{"key":"e_1_2_5_25_1","unstructured":"National Center for Birth Defects and Developmental Disabilities (NCBDDD).2006. 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