{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T21:35:57Z","timestamp":1771104957022,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T00:00:00Z","timestamp":1428278400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["2P42ES007381"],"award-info":[{"award-number":["2P42ES007381"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["PA 96043, PA 02081 and FOA DD09-001"],"award-info":[{"award-number":["PA 96043, PA 02081 and FOA DD09-001"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Gastroschisis is a birth defect where loops of bowel are protruding from the abdominal wall at birth. Previous research has suggested that gastroschisis cases can occur in clusters. The objective of this study was to identify if there were areas of elevated gastroschisis risk using data from the National Birth Defects Prevention Study (NBDPS), 1997 through 2007.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We obtained data on cases (<jats:italic>n<\/jats:italic>\u2009=\u2009371) through population\u2010based birth defects surveillance systems in Arkansas, California, and Utah; controls (<jats:italic>n<\/jats:italic>\u2009=\u20092359) were selected from the same geographic areas as cases. Mothers were interviewed on demographic information and exposures during pregnancy, including residential history. We used first trimester maternal addresses and generalized additive models to create a continuous map surface of odds ratios (OR) by smoothing over latitude and longitude. Permutation tests were used to assess whether location of maternal residence was important and identify locations with statistically significant ORs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In Arkansas, adjusted ORs in the southwest corner were 2.0 and the global deviance was not statistically significant (<jats:italic>p<\/jats:italic>\u2010value: 0.57). Adjusted ORs for California indicated areas of increased risk with ORs 1.3 (<jats:italic>p<\/jats:italic>\u2010value: 0.34). In Utah, the adjusted ORs were elevated (OR: 2.4) in the south\u2010eastern corner of the study area (<jats:italic>p<\/jats:italic>\u2010value: 0.34).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this study, while not statistically significant, suggest there were spatial variations in gastroschisis births. We cannot rule out that these variations were due to edge effects or residual confounding. Birth Defects Research (Part A) 103:544\u2013553, 2015. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdra.23375","type":"journal-article","created":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T16:47:19Z","timestamp":1428338839000},"page":"544-553","source":"Crossref","is-referenced-by-count":12,"title":["Spatial analysis of gastroschisis in the national birth defects prevention study"],"prefix":"10.1002","volume":"103","author":[{"given":"Mahsa M.","family":"Yazdy","sequence":"first","affiliation":[{"name":"Slone Epidemiology Center at Boston University Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha M.","family":"Werler","sequence":"additional","affiliation":[{"name":"Slone Epidemiology Center at Boston University Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcia L.","family":"Feldkamp","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Utah School of Medicine Salt Lake City Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary M","family":"Shaw","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bridget S.","family":"Mosley","sequence":"additional","affiliation":[{"name":"Department of Pediatrics College of Medicine, University of Arkansas for Medical Sciences, Arkansas Children's Hospital Research Institute Little Rock Arkansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronica M.","family":"Vieira","sequence":"additional","affiliation":[{"name":"Program in Public Health University of California Irvine California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The National Birth Defects Prevention Study","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-012-1196-3"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.01.026"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","unstructured":"BuggeM PetersenMB ChristensenMF.1994.Monozygotic twins discordant for gastroschisis: case report and review of the literature of twins and familial occurrence of gastroschisis.Am J Med Genet52:223\u2013226.","DOI":"10.1002\/ajmg.1320520219"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20294"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20582"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/15287394.2011.534424"},{"key":"e_1_2_6_8_1","first-page":"361","article-title":"A cluster study of gastroschisis: single center experience","volume":"106","author":"Chabra S","year":"2008","journal-title":"J Ky Med Assoc"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.02.012"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2009.186"},{"key":"e_1_2_6_11_1","first-page":"Environmental S","volume-title":"ArcGIS Desktop: release 10. Redlands","author":"ESRI","year":"2011"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39567.509074.25"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","unstructured":"FriedmanA DwanJB CarrS.2006.Analysis of gastroschisis case series for geographic clustering.Am J Obstet Gynecol195(Suppl 1):S229\u2013S229.","DOI":"10.1016\/j.ajog.2006.10.834"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.11.026"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7536.250"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31829cbbb4"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7210896"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1104305"},{"key":"e_1_2_6_19_1","first-page":"453","article-title":"Increasing prevalence at birth of gastroschisis in metropolitan Atlanta, 1968\u20131990","volume":"45","author":"Lynberg M","year":"1992","journal-title":"Teratology"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.90009"},{"key":"e_1_2_6_21_1","volume-title":"R: a language and environment for statistical computing","author":"R Development Core Team","year":"2009"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20587"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2009.01.034"},{"key":"e_1_2_6_24_1","volume-title":"Langman's medical embryology","author":"Sadler TW","year":"2011"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20612"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.10113"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.09.025"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320450414"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.11.037"},{"key":"e_1_2_6_30_1","first-page":"e1","article-title":"Agricultural\u2010related chemical exposures, season of conception, and risk of gastroschisis in Washington State","volume":"241","author":"Waller SA","year":"2010","journal-title":"Am J Obstet Gynecol 202"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-072X-5-26"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/155.1.26"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20114"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2014.10.001"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/phr\/116.S1.32"}],"container-title":["Birth Defects Research Part A: Clinical and Molecular Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdra.23375","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdra.23375","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T13:59:49Z","timestamp":1696600789000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdra.23375"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,6]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["10.1002\/bdra.23375"],"URL":"https:\/\/doi.org\/10.1002\/bdra.23375","archive":["Portico"],"relation":{},"ISSN":["1542-0752","1542-0760"],"issn-type":[{"value":"1542-0752","type":"print"},{"value":"1542-0760","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,6]]}}}