{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:44:49Z","timestamp":1789541089238,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,2,13]],"date-time":"2017-02-13T00:00:00Z","timestamp":1486944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2017,2,15]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Neural tube defects (NTDs) are one of the commonest birth defects. There was paucity of community\u2010based data on occurrence of NTDs in India, especially from rural parts of the country. Against this background, the current study was carried out with main objectives to determine the prevalence of NTDs and its specific types (anencephaly, spina bifida and encephalocele) in a rural community setting over the time period 2001 to 2014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a community\u2010based cross\u2010sectional study carried out in 28 villages of Ballabgarh Tehsil of Faridabad district in north India (population \u223c 96,000). A household survey was undertaken by trained multi\u2010purpose workers who enquired ever\u2010married women about history of conception with outcome as NTD during the study period. The probable case of NTD was determined using a colored pictorial card with photographs of different types of NTDs. These cases were confirmed by doctors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 26,946 live births occurred during the years 2001 to 2014. A total of 140 confirmed cases of NTDs were identified. The live birth prevalence of NTDs was 24.1 per 10,000 live births (95% confidence interval, 18.8\u201330.6). The birth prevalence of NTDs for the years 2008 to 2014 was 50.8 (95% confidence interval, 39.9\u201363.8) per 10,000 live and stillbirths. The most common type of NTD was found to be spina bifida followed by anencephaly and encephalocele.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found high prevalence of NTDs in rural community settings from north India for years 2001 to 2014.Birth Defects Research 109:203\u2013210, 2017.\u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdra.23578","type":"journal-article","created":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T16:48:52Z","timestamp":1479833332000},"page":"203-210","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of neural tube defects in a rural area of north india from 2001 to 2014: A population\u2010based survey"],"prefix":"10.1002","volume":"109","author":[{"given":"Shashi","family":"Kant","sequence":"first","affiliation":[{"name":"Comprehensive Rural Health Services Project, Ballabgarh (CRHSP\u2010B), Centre for Community Medicine All India Institute of Medical Sciences (AIIMS) New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Comprehensive Rural Health Services Project, Ballabgarh (CRHSP\u2010B), Centre for Community Medicine All India Institute of Medical Sciences (AIIMS) New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvind Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Comprehensive Rural Health Services Project, Ballabgarh (CRHSP\u2010B), Centre for Community Medicine All India Institute of Medical Sciences (AIIMS) New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Partha","family":"Haldar","sequence":"additional","affiliation":[{"name":"Comprehensive Rural Health Services Project, Ballabgarh (CRHSP\u2010B), Centre for Community Medicine All India Institute of Medical Sciences (AIIMS) New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravneet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Comprehensive Rural Health Services Project, Ballabgarh (CRHSP\u2010B), Centre for Community Medicine All India Institute of Medical Sciences (AIIMS) New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puneet","family":"Misra","sequence":"additional","affiliation":[{"name":"Centre for Community Medicine All India Institute of Medical Sciences New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neerja","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Paediatrics All India Institute of Medical Sciences New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118961"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23153"},{"key":"e_1_2_6_4_1","unstructured":"Census of India.(Internet) Sample Registration System. 2013. 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