{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T20:56:32Z","timestamp":1790974592892,"version":"4.1.0"},"reference-count":236,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,5,29]],"date-time":"2003-05-29T00:00:00Z","timestamp":1054166400000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research Pt C"],"published-print":{"date-parts":[[2003,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Embryonic induction, soluble and insoluble factors, receptors, and signal transduction are orchestrated for the morphogenesis of the cartilage elements. The interaction of cells with the extracellular matrix (ECM) may lead to altered cellular response to morphogens based on the formation of new adhesive contacts, or the uncoupling of cell\u2013matrix interactions. Hyaluronan's influence on cell behavior, and its intimate association with cells are accomplished by a wide variety of specific binding proteins for hyaluronan. The temporal expression of the hyaluronan receptor CD44 (which is expressed as several alternatively spliced variants) may be strategic to many of these cell\u2013matrix interactions during chondrogenesis. CD44 expression is temporally coincident with the reduction of intercellular spaces at the regions of future cartilage deposition. The spatial organization of CD44 at the cell surface may function to establish or regulate the structure of the pericellular matrix dependent on a hyaluronan scaffold. As the ECM is modified during embryogenesis, the cellular response to inductive signals may be altered. An uncoupling of chondrocyte\u2013hyaluronan interaction leads to chondrocytic chondrolysis. Thus, consideration of cell\u2013matrix interactions during chondrogenesis, in the light of our current understanding of the temporal and spatial expression of signaling morphogens, should become a promising focus of future research endeavors. Birth Defects Research (Part C) 69: 174\u2013196, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/bdrc.10013","type":"journal-article","created":{"date-parts":[[2003,5,30]],"date-time":"2003-05-30T10:04:55Z","timestamp":1054289095000},"page":"174-196","source":"Crossref","is-referenced-by-count":160,"title":["Hyaluronan and CD44: Strategic players for cell\u2013matrix interactions during chondrogenesis and matrix assembly"],"prefix":"10.1002","volume":"69","author":[{"given":"Cheryl B.","family":"Knudson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,5,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.117.4.1183"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1999.4641"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(77)90110-5"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/15537"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(90)90694-A"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.19.10116"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.29.20444"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(87)90240-5"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008208809016809"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.1.338"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.144.4.789"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.132.6.1199"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.9.6321"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/joca.2000.0348"},{"key":"e_1_2_12_16_1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1242\/jcs.96.3.527","article-title":"An analysis of chick limb bud intercellular adhesion underlying the establishment of cartilage aggregates in suspension culture","volume":"96","author":"Bee JA","year":"1990","journal-title":"J Cell Sci"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(86)90096-5"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1989.tb00010.x"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.2741\/A308"},{"key":"e_1_2_12_20_1","first-page":"9830","article-title":"Electron micrographic studies of cartilage proteoglycans","volume":"257","author":"Buckwalter JA","year":"1982","journal-title":"J Biol Chem"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI10272"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.115.5.1283"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.46.27734"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199808)41:8<1411::AID-ART10>3.0.CO;2-Z"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(68)90530-2"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.147.5.1109"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0945-053X(01)00172-X"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.116.4.1055"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.100.2.249"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1997.8525"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.126.17.3957"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(00)00276-3"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1053\/joca.1999.0306"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.10308"},{"key":"e_1_2_12_35_1","first-page":"617","volume-title":"Articular cartilage and osteoarthritis","author":"Dieppe P","year":"1992"},{"key":"e_1_2_12_36_1","first-page":"1","article-title":"Mechanisms of cartilage destruction and repair: the outlook for therapeutic interventions","volume":"3","author":"Dingle JT","year":"1993","journal-title":"Clin Rheumatol"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-618155-5.50010-6"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109627200"},{"key":"e_1_2_12_39_1","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1242\/dev.127.7.1337","article-title":"A model for anteroposterior patterning of the vertebrate limb based on sequential long\u2010 and short\u2010range Shh signalling and BMP signalling","volume":"127","author":"Drossopoulou G","year":"2000","journal-title":"Development"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1993.1189"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1997.12.7.1124"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780391117"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00225415"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2560153"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470513774.ch4"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.145.5.1103"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1993.1096"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.285.5430.1028"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.99.6.2114"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.8.3271"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3090963"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90403-L"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-78253-4_4"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-1878(200002)22:2<138::AID-BIES5>3.0.CO;2-4"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1993.tb07469.x"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199710)210:2<130::AID-AJA6>3.0.CO;2-H"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(72)90160-2"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1350905"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1770237"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.117.6.1343"},{"key":"e_1_2_12_61_1","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1016\/S0021-9258(19)78236-2","article-title":"Protein polysaccharide complex from bovine nasal cartilage. The function of glycoprotein in the formation of aggregates","volume":"244","author":"Hascall VC","year":"1969","journal-title":"J Biol Chem"},{"key":"e_1_2_12_62_1","first-page":"4242","article-title":"Aggregation of cartilage proteoglycans. II. Oligosaccharide competitors of the proteoglycan\u2010hyaluronic acid interaction","volume":"249","author":"Hascall VC","year":"1974","journal-title":"J Biol Chem"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/jss.400070110"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8832(11)80053-3"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.107.1.17"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-3770-0_13"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320340107"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(89)90040-6"},{"key":"e_1_2_12_69_1","first-page":"347","article-title":"The transmembrane hyaluronate receptor (CD44): multiple functions, multiple forms","volume":"3","author":"Haynes BF","year":"1991","journal-title":"Cancer Cells"},{"key":"e_1_2_12_70_1","first-page":"277","volume-title":"Extracellular matrix biochemistry","author":"Heinegard D","year":"1984"},{"key":"e_1_2_12_71_1","first-page":"239","volume-title":"Osteoarthritic disorders","author":"Heinegard D","year":"1995"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.115.4.769"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.98.1.91"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(87)90409-X"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.106.1.365"},{"key":"e_1_2_12_76_1","first-page":"183","volume-title":"Articular cartilage and osteoarthritis","author":"Hunziker EB","year":"1992"},{"key":"e_1_2_12_77_1","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1242\/jcs.107.9.2353","article-title":"The role of the cytoplasmic domain in regulating CD44 function","volume":"107","author":"Isacke CM","year":"1994","journal-title":"J Cell Sci"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.17.9875"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.35.25085"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)42893-1"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200111)44:11<2599::AID-ART440>3.0.CO;2-Y"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M108654200"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.30.18709"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199912)216:4\/5<499::AID-DVDY18>3.0.CO;2-S"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.106.2.319"},{"key":"e_1_2_12_86_1","doi-asserted-by":"crossref","first-page":"8113","DOI":"10.1016\/S0021-9258(18)83157-X","article-title":"Lymphoma protein kinase c is associated with the transmembrane glycoprotein, gp85, and may function in gp85\u2010ankyrin binding","volume":"264","author":"Kalomiris EL","year":"1989","journal-title":"J Biol Chem"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)67049-8"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(85)90401-4"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(87)90462-3"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.120.3.825"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.7.13.7691670"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1002040209"},{"key":"e_1_2_12_93_1","first-page":"34","article-title":"Changes in phosphorylation and actin\u2010association of CD44 with receptor occupancy on articular chondrocytes","volume":"22","author":"Knudson CB","year":"1997","journal-title":"Trans Orthop Res Soc"},{"key":"e_1_2_12_94_1","first-page":"161","volume-title":"The chemistry, biology and medical applications of hyaluronan and its derivatives","author":"Knudson CB","year":"1998"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1042\/bst0270142"},{"key":"e_1_2_12_96_1","first-page":"331","volume-title":"Hyaluronan 2000","author":"Knudson CB","year":"2000"},{"key":"e_1_2_12_97_1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1242\/jcs.99.2.227","article-title":"Assembly of a chondrocyte\u2010like pericellular matrix on non\u2010chondrogenic cells","volume":"99","author":"Knudson W","year":"1991","journal-title":"J Cell Sci"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.9.4003"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1996.0320"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200005)43:5<1165::AID-ANR27>3.0.CO;2-H"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-002-8403-0"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0945-053X(01)00186-X"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.7.3.383"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/0045-6039(84)90048-4"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/40.10.1146"},{"key":"e_1_2_12_106_1","first-page":"85","article-title":"A gradation of hyaluronate accumulation along the proximodistal axis of the embryonic chick limb bud","volume":"63","author":"Kosher RA","year":"1981","journal-title":"J Embryol Exp Morphol"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/0045-6039(82)90069-0"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.10030"},{"key":"e_1_2_12_109_1","first-page":"6.1","volume-title":"Rheumatology","author":"Kuettner KE","year":"1994"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(87)90256-9"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.15.8681"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119526"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470513385.ch2"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.6.7.1563592"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.54.5.429"},{"key":"e_1_2_12_116_1","first-page":"19","article-title":"CD44: a model for regulated adhesion function","volume":"3","author":"Lazaar AL","year":"1995","journal-title":"Immunologist"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.123.6.1899"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(00)00135-6"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(90)90085-O"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.2741\/A306"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1002\/1521-4141(200001)30:1<245::AID-IMMU245>3.0.CO;2-X"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)61467-5"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.7.9.8330681"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1995.1084"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1996.0156"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008209609028895"},{"key":"e_1_2_12_127_1","first-page":"215","volume-title":"Adult articular cartilage","author":"Maroudas A","year":"1979"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/bit.260330111"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)43775-1"},{"key":"e_1_2_12_130_1","first-page":"331","article-title":"Receptors for extracellular matrix components","volume":"257","author":"McDonald JA","year":"1989","journal-title":"Am J Physiol"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041330210"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1054\/ghir.2001.0250"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.126.23.5515"},{"key":"e_1_2_12_134_1","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1242\/jcs.107.11.3183","article-title":"Epican, a heparan\/chondroitin sulfate proteoglycan form of CD44, mediates cell\u2013cell adhesion","volume":"107","author":"Milstone L","year":"1994","journal-title":"J Cell Sci"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.172.1.69"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2002.0766"},{"key":"e_1_2_12_137_1","doi-asserted-by":"crossref","first-page":"33021","DOI":"10.1016\/S0021-9258(20)30092-2","article-title":"Aggrecan synthesized by mature bovine chondrocytes suspended in alginate","volume":"269","author":"Mok SS","year":"1994","journal-title":"J Biol Chem"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199610033351405"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(87)91632-9"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.31.21893"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200001)43:1<206::AID-ANR25>3.0.CO;2-1"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1053\/joca.1999.0281"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1177\/002215540205001004"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.120.1.177"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2744(70)90139-7"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200108159"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(85)90333-1"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008200009005288"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2000.9831"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109151200"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1996.0166"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.17.11566"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2000.9610"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.242401399"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1004"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2200597"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.1.55"},{"key":"e_1_2_12_158_1","doi-asserted-by":"crossref","first-page":"16661","DOI":"10.1016\/S0021-9258(18)37441-6","article-title":"Affinity and distribution of surface and intracellular hyaluronic acid receptors in isolated rat liver endothelial cells","volume":"263","author":"Raja RH","year":"1988","journal-title":"J Biol Chem"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(00)90051-9"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)41808-X"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3540017"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0398-247"},{"key":"e_1_2_12_163_1","first-page":"71","article-title":"Cartilage matrix deficiency (cmd): a new autosomal recessive lethal mutation in the mouse","volume":"43","author":"Rittenhouse E","year":"1978","journal-title":"J Embryol Exp Morphol"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0945-053X(01)00189-5"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9896(199608)179:4<396::AID-PATH606>3.0.CO;2-G"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/31.4.231"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-0436.2001.690203.x"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2001.0500"},{"key":"e_1_2_12_169_1","first-page":"3","volume-title":"Articular cartilage biochemistry","author":"Schenk RK","year":"1986"},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.100.2.598"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6603(08)60508-5"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.24.12160"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199609)207:1<114::AID-AJA11>3.0.CO;2-0"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.15.10738"},{"key":"e_1_2_12_175_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.10116"},{"key":"e_1_2_12_176_1","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1042\/bst0230831","article-title":"Modulation of hyaluronan receptor, CD44, by its transmembrane and cytoplasmic domains","volume":"23","author":"Sheikh H","year":"1995","journal-title":"Biochem Soc Trans"},{"key":"e_1_2_12_177_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.7.1058"},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1996.0350"},{"key":"e_1_2_12_179_1","first-page":"35","volume-title":"Articular cartilage and disease","author":"Shinomura T","year":"1992"},{"key":"e_1_2_12_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(81)90375-4"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2230617"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02618173"},{"key":"e_1_2_12_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(80)90324-3"},{"key":"e_1_2_12_184_1","first-page":"277","volume-title":"The role of extracellular matrix in development","author":"Solursh M","year":"1984"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/0045-6039(84)90025-3"},{"key":"e_1_2_12_186_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.38.23400"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1997.4696"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(94)90307-7"},{"key":"e_1_2_12_189_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1998.00093.x"},{"key":"e_1_2_12_190_1","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1242\/jcs.108.7.2663","article-title":"Perlecan is a component of cartilage matrix and promotes chondrocyte attachment","volume":"108","author":"SundarRaj N","year":"1995","journal-title":"J Cell Sci"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.174.4.859"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.5.2863"},{"key":"e_1_2_12_193_1","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1242\/jcs.110.18.2261","article-title":"Regulated expression of fibronectin, laminin and related integrin receptors during the early chondrocyte differentiation","volume":"110","author":"Tavella S","year":"1997","journal-title":"J Cell Sci"},{"key":"e_1_2_12_194_1","first-page":"273","volume-title":"Articular cartilage biochemistry","author":"Thonar EJ\u2010MA","year":"1986"},{"key":"e_1_2_12_195_1","first-page":"581","article-title":"An analysis of the condensation process during chondrogenesis in the embryonic chick hind limb","volume":"33","author":"Thorogood PV","year":"1975","journal-title":"J Embryol Exp Morphol"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(82)90217-2"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(72)90071-1"},{"key":"e_1_2_12_198_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-0881-2_10"},{"key":"e_1_2_12_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/0955-0674(90)90081-O"},{"key":"e_1_2_12_200_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-3770-0_10"},{"key":"e_1_2_12_201_1","first-page":"1","volume-title":"Developmental patterning of the vertebrate limb","author":"Toole BP","year":"1992"},{"key":"e_1_2_12_202_1","first-page":"43","volume-title":"The role of the extracellular matrix in development","author":"Toole BP","year":"1984"},{"key":"e_1_2_12_203_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470513774.ch9"},{"key":"e_1_2_12_204_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.11.6296"},{"key":"e_1_2_12_205_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.126.2.391"},{"key":"e_1_2_12_206_1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1242\/dev.126.2.221","article-title":"Conserved regulation of mesenchymal gene expression by FGF\u20108 in face and limb development","volume":"126","author":"Tucker AS","year":"1999","journal-title":"Development"},{"key":"e_1_2_12_207_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12319402"},{"key":"e_1_2_12_208_1","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1182\/blood.V81.2.446.bloodjournal812446","article-title":"Expression and function of a receptor for hyaluronan\u2010mediated motility on normal and malignant B lymphocytes","volume":"81","author":"Turley EA","year":"1993","journal-title":"Blood"},{"key":"e_1_2_12_209_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R100038200"},{"key":"e_1_2_12_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(78)90438-X"},{"key":"e_1_2_12_211_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.82.2.475"},{"key":"e_1_2_12_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)85527-8"},{"key":"e_1_2_12_213_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(81)90248-2"},{"key":"e_1_2_12_214_1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1242\/jcs.56.1.177","article-title":"Interaction of hyaluronate with the surface of simian virus 40\u2010 transformed 3T3 cells: aggregation and binding studies","volume":"56","author":"Underhill CB","year":"1982","journal-title":"J Cell Sci"},{"key":"e_1_2_12_215_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041100204"},{"key":"e_1_2_12_216_1","doi-asserted-by":"crossref","first-page":"8086","DOI":"10.1016\/S0021-9258(20)82031-6","article-title":"Effect of detergent solubilization on the hyaluronanate\u2010binding protein from membranes of simian virus 40\u2010transformed 3T3 cells","volume":"258","author":"Underhill CB","year":"1983","journal-title":"J Biol Chem"},{"key":"e_1_2_12_217_1","doi-asserted-by":"crossref","first-page":"13142","DOI":"10.1016\/S0021-9258(18)45179-4","article-title":"The hyaluronate receptor is identical to a glycoprotein of 85,000mr (gp 85) as shown by a monoclonal antibody that interferes with binding activity","volume":"262","author":"Underhill CB","year":"1987","journal-title":"J Biol Chem"},{"key":"e_1_2_12_218_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.103.2.293"},{"key":"e_1_2_12_219_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1993.1032"},{"key":"e_1_2_12_220_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.70.5.1569"},{"key":"e_1_2_12_221_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.13.6943"},{"key":"e_1_2_12_222_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.jbchem.a022166"},{"key":"e_1_2_12_223_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-0436.1996.6010017.x"},{"key":"e_1_2_12_224_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.22.13997"},{"key":"e_1_2_12_225_1","doi-asserted-by":"crossref","first-page":"9808","DOI":"10.1074\/jbc.M211462200","article-title":"A blocking antibody to the hyaluronan (HA) receptor for endocytosis (HARE) inhibits HA clearance by perfused liver","volume":"278","author":"Weigel J","journal-title":"J Biol Chem"},{"key":"e_1_2_12_226_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.148.4.679"},{"key":"e_1_2_12_227_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.119.2.295"},{"key":"e_1_2_12_228_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041560224"},{"key":"e_1_2_12_229_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780370414"},{"key":"e_1_2_12_230_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)36998-3"},{"key":"e_1_2_12_231_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0945-053X(97)90001-9"},{"key":"e_1_2_12_232_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00117a039"},{"key":"e_1_2_12_233_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199610)207:2<204::AID-AJA8>3.0.CO;2-L"},{"key":"e_1_2_12_234_1","doi-asserted-by":"publisher","DOI":"10.1016\/0047-6374(86)90064-3"},{"key":"e_1_2_12_235_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.49.33054"},{"key":"e_1_2_12_236_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.02-03-0048"},{"key":"e_1_2_12_237_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1989.tb08447.x"}],"container-title":["Birth Defects Research Part C: Embryo Today: Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdrc.10013","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdrc.10013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T12:02:36Z","timestamp":1700222556000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdrc.10013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,5]]},"references-count":236,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,5]]}},"alternative-id":["10.1002\/bdrc.10013"],"URL":"https:\/\/doi.org\/10.1002\/bdrc.10013","archive":["Portico"],"relation":{},"ISSN":["1542-975X","1542-9768"],"issn-type":[{"value":"1542-975X","type":"print"},{"value":"1542-9768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,5]]}}}