{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T03:28:38Z","timestamp":1778642918438,"version":"3.51.4"},"reference-count":151,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T00:00:00Z","timestamp":1482969600000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research Pt C"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Medically assisted procreation significantly contributes to an increase in twin pregnancies. One of the major factors contributing to more twin births is the use of fertility treatments. Twin pregnancy is not without a risk for fetal organ development and the health outcome of new\u2010borns, children, and adults. Multiple pregnancies are associated with an increased risk of developmental complications, such as perinatal mortality, premature births, and low birth weight. Oxidative stress is involved in pregnancy disorders such as abortion, intrauterine growth retardation, and prenatal mortality. The link between oxidative stress and prenatal development, poorly perceived in the medical community, is a major problem in human reproductive medicine and health outcomes. The sex\u2010based considerations and analyses are also, often neglected in biomedical research. In addition, fetal sexual dimorphism in antioxidant pathways following intrauterine exposure to environmental pollutants has not been explored. This is an important area of research because sexually dimorphic antioxidant adaptive responses to early life exposure\u2010induced oxidative stress may have long\u2010term effects on offspring health outcome and increase the risk of non\u2010communicable diseases in men and women. This concept is useful, since it may open the avenue to develop antenatal antioxidant therapeutic strategies to developmental disorders and complications related to multiple pregnancies, and in association with acute or chronic environmental exposure. This article reviews the status of research, supporting data, possible pathogenic mechanisms, and future perspectives in the proposed area. Birth Defects Research (Part C) 108:351\u2013364, 2016. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/bdrc.21142","type":"journal-article","created":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T06:37:13Z","timestamp":1694846233000},"page":"351-364","source":"Crossref","is-referenced-by-count":14,"title":["Multiple exposures to environmental pollutants and oxidative stress: Is there a sex specific risk of developmental complications for fetuses?"],"prefix":"10.1002","volume":"108","author":[{"given":"Ka\u00efs H.","family":"Al\u2010Gubory","sequence":"first","affiliation":[{"name":"Ka\u00efs H. Al\u2010Gubory is from the UMR Biologie du D\u00e9veloppement et Reproduction Institut National de la Recherche Agronomique, Universit\u00e9 Paris Saclay Jouy\u2010en\u2010Josas France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,29]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"1","volume-title":"Studies on women's health, oxidative stress in applied basic research and clinical practice","author":"Al\u2010Gubory KH.","year":"2013"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2014.03.002"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2010.06.001"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2015.1130224"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD99079"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod29.3.548"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-6238(02)00095-3"},{"key":"e_1_2_9_9_1","first-page":"18103","article-title":"Preimplantation exposures of murine embryos to estradiol or methoxychlor change postnatal development","author":"Amstislavsky SY","year":"2004","journal-title":"Reprod Toxicol"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2004.45.5.776"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211378"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1550-8579(07)80057-X"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2013.10.029"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(02)01356-4"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.6b02253"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.10952"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/es0485311"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2011.02.001"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/136.6.1636S"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2015.6289"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.115.135848"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/01902148.2014.893383"},{"key":"e_1_2_9_23_1","first-page":"454","article-title":"Biologic and physiologic role of taurine and its derivates","volume":"117","author":"Ca\u00f1as P","year":"1989","journal-title":"Rev Med Chil"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1386.008"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5742(96)00050-6"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054374"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/15368370802473463"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crvi.2008.03.009"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510250126"},{"key":"e_1_2_9_30_1","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1046\/j.1432-1327.1999.00199.x","article-title":"Hydroxyl-radical production in physiological reactions. A novel function of peroxidase","volume":"260","author":"SX Chen","year":"1999","journal-title":"Eur J Biochem"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/509282a"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4789532"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu014"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(73)90517-6"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(90)90088-C"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1205575"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD04101"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2010.04.001"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2012.09.083"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod61.3.651"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-1045com"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1042\/cs0940149"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00018.2001"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdrc.20118"},{"key":"e_1_2_9_45_1","first-page":"71","article-title":"The biological oxidation of hypotaurine to taurine: hypotaurine as an antioxidant","volume":"179","author":"Fellman JH","year":"1985","journal-title":"Prog Clin Biol Res"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.02.017"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/JPN.0000000000000153"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx7002323"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.712350"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2006.12.004"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-014-0112-7"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-016-0095-2"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32745"},{"key":"e_1_2_9_54_1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1080\/10715769900300851","article-title":"Glutathione\u2010dependent enzymes represent a co\u2010ordinately regulated defence against oxidative stress","volume":"31","author":"JD Hayes","year":"1999","journal-title":"Free Radic Res"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1995.tb01572.x"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1289\/EHP300"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.1997.d01-17.x"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2016.07.013"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0967fje"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.7065"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2005.05.013"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M010120200"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2011.03.001"},{"key":"e_1_2_9_64_1","first-page":"75","article-title":"Tobacco smoking\u2013a risk factor for intrauterine growth retardation, preterm delivery and low birth weight","volume":"67","author":"Kalinka J","year":"1996","journal-title":"Ginekol Pol"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(89)90056-X"},{"key":"e_1_2_9_66_1","first-page":"383","article-title":"Role of oxidative injury in affecting the foetal & placental weights on exposure to tobacco smoke","volume":"65","author":"Khan HM","year":"2015","journal-title":"J Pak Med Assoc"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.24401"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0823hyp"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015970023889"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420520304"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1401940115"},{"key":"e_1_2_9_72_1","first-page":"98","article-title":"Placental transfer of drugs, alcohol, and components of cigarette smoke and their effects on the human fetus","volume":"60","author":"Kuhnert BR","year":"1985","journal-title":"NIDA Res Monogr"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.12.005"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.2741\/s465"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.133553"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.6000"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2008.01.028"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2015.02.006"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2006.11.051"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1159\/000457063"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2005.08.020"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1996.tb01942.x"},{"key":"e_1_2_9_83_1","first-page":"1","article-title":"Three decades of twin births in the United States, 1980\u20102009","volume":"80","author":"Martin JA","year":"2012","journal-title":"NCHS Data Brief"},{"key":"e_1_2_9_84_1","first-page":"6049","article-title":"Superoxide dismutase. An enzymatic function for erythrocuprein","volume":"244","author":"McCord I","year":"1969","journal-title":"J Biol Chem"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(94)90079-5"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10658"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.184.4138.812"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2016.04.103"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000128981.38670.28"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD05030"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2015.45"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh129"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-016-0073-y"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.5742"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2006.09.008"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx010022e"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2012.05.019"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2001.tb02292.x"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420190305"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1203396109"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70193-5"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-006-0351-5"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrfmmm.2005.06.012"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.9910717"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2014.12.020"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.10.001"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-9351(78)90159-7"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2007.05393.x"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-014-0105-z"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2016.07.009"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8111"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016340903505748"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13181-011-0143-9"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2013.07.005"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2016.01.009"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2012.03.012"},{"key":"e_1_2_9_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2004.11.011"},{"key":"e_1_2_9_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2009.09.003"},{"key":"e_1_2_9_119_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10960"},{"key":"e_1_2_9_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2007.04.182"},{"key":"e_1_2_9_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2015.03.017"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1080\/08958370802526881"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2007.10.010"},{"key":"e_1_2_9_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2013.04.004"},{"key":"e_1_2_9_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(80)90628-6"},{"key":"e_1_2_9_126_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000109427.85586.71"},{"key":"e_1_2_9_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(01)00516-9"},{"key":"e_1_2_9_128_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.27.835"},{"key":"e_1_2_9_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7643-8340-4_6"},{"key":"e_1_2_9_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2598"},{"key":"e_1_2_9_131_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.17.10609"},{"key":"e_1_2_9_132_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451100688X"},{"key":"e_1_2_9_133_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10661-015-4369-x"},{"key":"e_1_2_9_134_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10517-007-0431-1"},{"key":"e_1_2_9_135_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715760500188671"},{"key":"e_1_2_9_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2006.07.001"},{"key":"e_1_2_9_137_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867053764635"},{"key":"e_1_2_9_138_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00203.2007"},{"key":"e_1_2_9_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2015.10.010"},{"key":"e_1_2_9_140_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.108.069591"},{"key":"e_1_2_9_141_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S40214"},{"key":"e_1_2_9_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-006-0169-1"},{"key":"e_1_2_9_143_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.97105514"},{"key":"e_1_2_9_144_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.115.002180"},{"key":"e_1_2_9_145_1","doi-asserted-by":"crossref","first-page":"4791","DOI":"10.1016\/S0021-9258(19)43735-6","article-title":"Mitochondrial superoxide dismutase. Site of synthesis and intramitochondrial localisation","volume":"248","author":"Weisiger RA","year":"1973","journal-title":"J Biol Chem"},{"key":"e_1_2_9_146_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088582"},{"key":"e_1_2_9_147_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.7751"},{"key":"e_1_2_9_148_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1995.9935976"},{"key":"e_1_2_9_149_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.5217506"},{"key":"e_1_2_9_150_1","doi-asserted-by":"publisher","DOI":"10.1248\/jhs.48.317"},{"key":"e_1_2_9_151_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.192.7.1001"},{"key":"e_1_2_9_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2006.04.029"}],"container-title":["Birth Defects Research Part C: Embryo Today: Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdrc.21142","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T06:37:27Z","timestamp":1694846247000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdrc.21142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":151,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1002\/bdrc.21142"],"URL":"https:\/\/doi.org\/10.1002\/bdrc.21142","archive":["Portico"],"relation":{},"ISSN":["1542-975X","1542-9768"],"issn-type":[{"value":"1542-975X","type":"print"},{"value":"1542-9768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12]]}}}