{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:39:51Z","timestamp":1774867191105,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,5,10]],"date-time":"2005-05-10T00:00:00Z","timestamp":1115683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioelectromagnetics"],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A study of the effect of weak, interrupted sinusoidal low frequency magnetic field (ISMF) stimulation on regeneration of the rat sciatic nerve was carried out. In the experiment, 60 Wistar rats were used: 24 rats underwent unilateral sciatic nerve transection injury and immediate surgical nerve repair, 24 rats underwent unilateral sciatic nerve crush injury, and the remaining 12 rats underwent a sham surgery. Half of the animals (<jats:italic>n<\/jats:italic>\u2009=\u200912) with either sciatic nerve lesion were randomly chosen and exposed between a pair of Helmholtz coils for 3 weeks post\u2010injury, 4 h\/day, to an interrupted (active period to pause ratio\u2009=\u20091.4 s\/0.8 s) sinusoidal 50 Hz magnetic field of 0.5 mT. The other half of the animals (<jats:italic>n<\/jats:italic>\u2009=\u200912) and six rats with sham surgery were used for two separate controls. Functional recovery was followed for 6 weeks for the crush injuries and 7\u00bd months for the transection injuries by video assisted footprint analysis in static conditions and quantified using a recently revised static sciatic index (SSI) formula. We ascertained that the magnetic field influence was weak, but certainly detectable in both injury models. The accuracy of ISMF influence detection, determined by the one\u2010way repeated measures ANOVA test, was better for the crush injury model: <jats:italic>F<\/jats:italic>(1, 198)\u2009=\u20099.0144, <jats:italic>P<\/jats:italic>\u2009=\u2009.003, than for the transection injury model: <jats:italic>F<\/jats:italic>(1, 198)\u2009=\u20096.4826, <jats:italic>P<\/jats:italic>\u2009=\u2009.012. The Student\u2013Newman\u2013Keuls range test for each response day yielded significant differences (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05) between the exposed and control groups early in the beginning of functional recovery and later on from the points adjacent to the beginning of the plateau, or 95% of functional recovery, and the end of observation. These differences probably reflect the ISMF systemic effect on the neuron cell bodies and increased and more efficient reinnervation of the periphery. 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