{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T12:53:38Z","timestamp":1761310418169},"reference-count":54,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2007,5,9]],"date-time":"2007-05-09T00:00:00Z","timestamp":1178668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioelectromagnetics"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The use of induction heater (IH) cook tops in homes has become widespread, especially in Japan, but there are concerns about the safety of intermediate frequency (IF) electromagnetic fields associated with these cooking appliances. Since the cellular genotoxicity of IF magnetic fields has not been examined in cultured cells, we examined the effects of these fields at a magnetic flux density of 532\u2009\u00b1\u200920 \u03bcT at 23 kHz, using an exposure unit with a built\u2010in CO<jats:sub>2<\/jats:sub> incubator. Exposure to the IF magnetic field at 532 \u00b5T for 2 h did not affect the growth of CHO\u2010K1 cells and caused no mutagenic effects in bacterial mutation assays. Exposure to the IF magnetic field for 2 h induced neither single nor double DNA strand breaks in comet assays, and caused no significant change in the mutation frequency at the HPRT locus compared to sham exposure. The magnetic field used in this study is more than 80 times higher than the level recommended as safe in the International Commission on Non\u2010ionizing Radiation Protection (ICNIRP) guidelines. From these results, we suggest that exposure to an IF magnetic field for 2 h does not cause cellular genotoxicity in bacteria and in Chinese hamster cells. However, the possibility of effects on other cellular functions remains, and further studies on the cellular effects of IF magnetic fields are required. Bioelectromagnetics 28:529\u2013537, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/bem.20334","type":"journal-article","created":{"date-parts":[[2007,5,9]],"date-time":"2007-05-09T17:50:47Z","timestamp":1178733047000},"page":"529-537","source":"Crossref","is-referenced-by-count":24,"title":["Magnetic fields generated by an induction heating (IH) cook top do not cause genotoxicity in vitro"],"prefix":"10.1002","volume":"28","author":[{"given":"Junji","family":"Miyakoshi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emi","family":"Horiuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehisa","family":"Nakahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Sakurai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,5,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1161(75)90046-1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.2131\/jts.26.323"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1218(97)00002-5"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1776"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1040820218"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(76)90105-6"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1161(93)90150-X"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.2250160409"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(00)01007-9"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2000.3455"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-7992(94)90067-1"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.2250140303"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199712)32:6<681::AID-AJIM16>3.0.CO;2-Y"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199710)32:4<403::AID-AJIM11>3.0.CO;2-7"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000225804"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9926(199811)58:5<190::AID-TERA5>3.0.CO;2-I"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.2250140304"},{"key":"e_1_2_1_19_1","first-page":"494","article-title":"Guidelines for limiting exposure to time\u2010varying electric, magnetic, and electromagnetic fields (up to 3000 GHz)","volume":"74","author":"ICNIRP","year":"1998","journal-title":"Health Phys"},{"key":"e_1_2_1_20_1","first-page":"215","article-title":"Exposure to power frequency magnetic field (50 Hz, 40 mT) did not cause point mutation in bacteria","volume":"23","author":"Ikehata M","year":"2001","journal-title":"Environ Mutagen Res"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-186X(1997)18:6<410::AID-BEM2>3.0.CO;2-5"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.10164"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/16.6.1281"},{"key":"e_1_2_1_24_1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1248\/yakushi1947.119.10_763","article-title":"Analysis of micronuclei induced under hyperthermic conditions in human lymphocyte culture by fluorescence in situ hybridization (FISH) and spectral karyotyping (SKY) methods","volume":"119","author":"Komae N","year":"1999","journal-title":"Yakugaku Zasshi"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2004.176"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2003.07.009"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.2250160309"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/095530096145814"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-186X(1997)18:6<446::AID-BEM7>3.0.CO;2-2"},{"key":"e_1_2_1_30_1","unstructured":"LeitgebN JuutilainenJ HietanenM KarpovicJ ThuroczyG GryzK.2006.Evaluation of relevant results from projects on the effects of IF exposure. 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