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Previous studies on skin keratinocytes showed that MMW could impact the mRNA expression of Transient Receptor Potential cation channel subfamily Vanilloid, member 2 (TRPV2). Here, we investigated the effect of MMW exposure on this marker, as well as on other membrane receptors such as Transient Receptor Potential cation channel subfamily Vanilloid, member 1 (TRPV1) and purinergic receptor P2X, ligand\u2010gated ion channel, 3 (P2\u2009\u00d7\u20093). We exposed the Neuroscreen\u20101 cell line (a PC12 subclone), in order to evaluate if acute MMW exposures could impact expression of these membrane receptors at the protein level. Proteotoxic stress\u2010related chaperone protein Heat Shock Protein 70 (HSP70) expression level was also assessed. We used an original high\u2010content screening approach, based on fluorescence microscopy, to allow cell\u2010by\u2010cell analysis and to detect any cell sub\u2010population responding to exposure. Immunocytochemistry was done after 24\u2009h MMW exposure of cells at 60.4\u2009GHz, with an incident power density of 10\u2009mW\/cm<jats:sup>2<\/jats:sup>. Our results showed no impact of MMW exposure on protein expressions of HSP70, TRPV1, TRPV2, and P2\u2009\u00d7\u20093. Moreover, no specific cell sub\u2010populations were found to express one of the studied markers at a different level, compared to the rest of the cell populations. However, a slight insignificant increase in HSP70 expression and an increase in protein expression variability within cell population were observed in exposed cells, but controls showed that this was related to thermal effect. Bioelectromagnetics. 37:444\u2013454, 2016. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bem.21995","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T14:18:41Z","timestamp":1470233921000},"page":"444-454","source":"Crossref","is-referenced-by-count":13,"title":["Impact of 60\u2010GHz millimeter waves on stress and pain\u2010related protein expression in differentiating neuron\u2010like cells"],"prefix":"10.1002","volume":"37","author":[{"given":"Alexis J.","family":"Haas","sequence":"first","affiliation":[{"name":"Transcription, Environment Cancer Group Institute of Research in Environmental and Occupational Health\u2014IRSET, INSERM University of Rennes 1 Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Le Page","sequence":"additional","affiliation":[{"name":"Transcription, Environment Cancer Group Institute of Research in Environmental and Occupational Health\u2014IRSET, 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