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In an effort to investigate this combination, we conducted a study to evaluate the effectiveness of electrical stimulation and Schwann\u2010like cell transplantation in female Wistar albino rats. Our study consisted of five groups of rats: a sham group, an injury group, an electrical stimulation group, a Schwann\u2010like cell group, and a combination group. The experimental groups received electrical stimulation, Schwann\u2010like cell transplantation, or both. The animals sciatic function index was evaluated during a 6\u2010week recovery period, and nerve conduction velocity, wet muscle mass, and nerve tissues were also analyzed. The results of the study showed that all experimental groups had a faster functional recovery compared to the injury group, although the difference between groups was not statistically significant. Both the combination group and the Schwann\u2010like cell transplantation group had a higher nerve conduction velocity compared to the other experimental groups. However, there was no significant difference between the combination and Schwann\u2010like cell transplantation groups. Nonetheless, histological analysis showed a better axonal reorganization in the combination group. The study provides preliminary evidence of the potential benefits of combining electrical stimulation and Schwann\u2010like cell transplantation in treating severe nerve injuries. However, further studies with larger sample sizes are needed to confirm these findings and optimize the treatment parameters.<\/jats:p>","DOI":"10.1002\/bem.22479","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T05:50:26Z","timestamp":1689745826000},"page":"192-203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of combined effects of brief electrical stimulation and Schwann\u2010like cells on sciatic nerve injury model"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2645-1988","authenticated-orcid":false,"given":"Mahmut Alp","family":"Kilic","sequence":"first","affiliation":[{"name":"Faculty of Medicine Biophysics Department Aydin Adnan Menderes University Aydin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aynur","family":"Abdulova","sequence":"additional","affiliation":[{"name":"Department of 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