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Three distinct whole\u2010body EMFs were applied for 2 weeks on growing mice. Structural, geometric, and material properties of the femora, tibiae, and humeri of suspended mice were altered compared to controls. Comparison of suspended mice and mice subjected to caloric restriction indicates that the changes in caloric intake do not explain either the suspension or the field\u2010induced effects. In agreement with past studies, rather, unloading appears to cause the suspension effects and to be addressed by the EMFs. The EMF effects on bone properties were apparently frequency dependent, with the lower two fundamental frequencies (260 and 910 Hz) altering, albeit slightly, the suspension\u2010induced bone effects. The fields are not apparently optimized for frequency, etc., with respect to therapeutic potential; however, suspension provides a model system for further study of the in vivo effects of EMFs. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/bem.2250160303","type":"journal-article","created":{"date-parts":[[2006,2,4]],"date-time":"2006-02-04T00:51:19Z","timestamp":1139014279000},"page":"152-159","source":"Crossref","is-referenced-by-count":2,"title":["Suspension osteopenia in mice: Whole body electromagnetic field effects"],"prefix":"10.1002","volume":"16","author":[{"given":"S. J.","family":"Simske","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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