{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:02:36Z","timestamp":1787068956987,"version":"build-2736575974"},"reference-count":50,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/P009808\/1"],"award-info":[{"award-number":["BB\/P009808\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioEssays"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Sex chromosomes in plants have been known for a century, but only recently have we begun to understand the mechanisms behind sex determination in dioecious plants. Here, we discuss evolution of sex determination, focusing on\n                    <jats:italic>Silene latifolia<\/jats:italic>\n                    , where evolution of separate sexes is consistent with the classic \u201ctwo mutations\u201d model\u2014a loss of function male sterility mutation and a gain of function gynoecium suppression mutation, which turned an ancestral hermaphroditic population into separate males and females. Interestingly, the gynoecium suppression function in\n                    <jats:italic>S. latifolia<\/jats:italic>\n                    evolved via loss of function in at least two sex\u2010linked genes and works via gene dosage balance between sex\u2010linked, and autosomal genes. This system resembles X\/A\u2010ratio\u2010based sex determination systems in\n                    <jats:italic>Drosophila<\/jats:italic>\n                    and\n                    <jats:italic>Rumex<\/jats:italic>\n                    , and could represent a steppingstone in the evolution of X\/A\u2010ratio\u2010based sex determination from an active Y system.\n                  <\/jats:p>","DOI":"10.1002\/bies.202300111","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T06:03:02Z","timestamp":1694412182000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Evolution of sex\u2010determination in dioecious plants: From active Y to X\/A balance?"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5876-7755","authenticated-orcid":false,"given":"Yusuke","family":"Kazama","sequence":"first","affiliation":[{"name":"Graduate school of Bioscience and Biotechnology Fukui Prefectural University  Eiheiji\u2010cho Fukui Japan"},{"name":"RIKEN Nishina Center  Wako Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiki","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Graduate school of Bioscience and Biotechnology Fukui Prefectural University  Eiheiji\u2010cho Fukui Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitry A.","family":"Filatov","sequence":"additional","affiliation":[{"name":"Department of Biology University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"issue":"2819","key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/112687c0","article-title":"Sex chromosomes in plants","volume":"112","author":"Blackburn K. 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