{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:56:02Z","timestamp":1790420162709,"version":"4.1.0"},"reference-count":141,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["810296"],"award-info":[{"award-number":["810296"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioEssays"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Plant stem cell homeostasis is a tightly controlled process governed by a complex network of transcription factors, hormones, signaling molecules, and various environmental factors. Among these, nitric oxide (NO) and redox signaling have emerged as critical regulators. This review examines the multifaceted role of NO in maintaining plant stem cell homeostasis, focusing on its influence through redox dynamics, DNA methylation, and hormonal regulation. We also explore the intricate cross\u2010talk between NO signaling and other key pathways, including environmental stimuli and the target of rapamycin (TOR) pathway, in balancing stem cell maintenance and differentiation within both shoot and root meristems. Additionally, we discuss NO's involvement in post\u2010translational modifications and transcriptional regulation, offering insights into its broader role in plant growth and development.<\/jats:p>","DOI":"10.1002\/bies.70048","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T09:30:32Z","timestamp":1754040632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Hidden Architects: Nitric Oxide and Redox Dynamics in Plant Stem Cell Homeostasis"],"prefix":"10.1002","volume":"47","author":[{"given":"Jian","family":"Zeng","sequence":"first","affiliation":[{"name":"Department of Stem Cell Biology Centre For Organismal Studies Heidelberg University  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin'Ai","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Stem Cell Biology Centre For Organismal Studies Heidelberg University  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3667-187X","authenticated-orcid":false,"given":"Jan U.","family":"Lohmann","sequence":"additional","affiliation":[{"name":"Department of Stem Cell Biology Centre For Organismal Studies Heidelberg University  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/415751a"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.07.070"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.289.5479.617"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80700-X"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.17258511"},{"key":"e_1_2_12_7_1","doi-asserted-by":"crossref","unstructured":"G.Daum A.Medzihradszky T.Suzaki andJ. U.Lohmann \u201cA Mechanistic Framework for Noncell Autonomous Stem Cell Induction inArabidopsis \u201dProceedings of the National Academy of Sciences of the United States of America111(2014):14619\u201314624.","DOI":"10.1073\/pnas.1406446111"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2164"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80115-4"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80865-X"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature06206"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.03.060"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2021.04.016"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09126"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2018.04.006"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.104683"},{"key":"e_1_2_12_17_1","doi-asserted-by":"crossref","unstructured":"S. P.Gordon V. S.Chickarmane C.Ohno andE. MMeyerowitz \u201cMultiple Feedback Loops Through Cytokinin Signaling Control Stem Cell Number Within theArabidopsisShoot Meristem \u201dProceedings of the National Academy of Sciences of the United States of America106(2009):16529\u201316534.","DOI":"10.1073\/pnas.0908122106"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2009.11.016"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04270"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2010.03.012"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2014.01.013"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13074-9"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1164147"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature06943"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2020.04.004"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.867901"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(02)01125-9"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1143409"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.06.023"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2010.04367.x"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.15.00415"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-021-00985-z"},{"key":"e_1_2_12_33_1","doi-asserted-by":"crossref","unstructured":"B.Belda\u2010Palaz\u00f3n M.Costa T.Beeckman et\u00a0al. \u201cABA Represses TOR and Root Meristem Activity Through Nuclear Exit of the SnRK1 Kinase \u201dProceedings of the National Academy of Sciences of the United States of America119(2022):2204862119.","DOI":"10.1073\/pnas.2204862119"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-023-01360-w"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.19004"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2009.06.006"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.109.072066"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.111.177741"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2018.09.010"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppl.13050"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2021.03.009"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-43705-1"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erae139"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/mp\/sss148"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.114.247445"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erv213"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppl.12958"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgg.2022.02.023"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erac508"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2024.108504"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/15592324.2024.2329841"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.13903"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/pce.12707"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2017.01582"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/pce.12715"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12045-4"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants10020360"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-022-01135-9"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2024.102510"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.105.033589"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00074-w"},{"key":"e_1_2_12_62_1","article-title":"Spatiotemporal Characteristics Determining the Multifaceted Nature of Reactive Oxygen, Nitrogen, and Sulfur Species in Relation to Proton Homeostasis","volume":"42","author":"Yamasaki H.","year":"2025","journal-title":"Antioxid Redox Signaling"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2003638"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2011.06.015"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3054.2009.01313.x"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/35041687"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24054782"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erx420"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2006.09.009"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-8137.2003.00804.x"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.10.020"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201695955"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1240667"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.12.105"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1819-6"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2313092121"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2019.09.006"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes10030190"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002243"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2015.01178"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/nplants.2016.58"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2019103667"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-17963-2"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2022.102267"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-024-01737-8"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.15.00026"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1101\/2024.07.30.605885"},{"key":"e_1_2_12_88_1","doi-asserted-by":"crossref","unstructured":"M.Fern\u00e1ndez\u2010Marcos L.Sanz D. R.Lewis et\u00a0al. \u201cNitric Oxide Causes Root Apical Meristem Defects and Growth Inhibition While Reducing PIN\u2010FORMED 1 (PIN1)\u2010Dependent Acropetal Auxin Transport \u201dProceedings of the National Academy of Sciences of the United States of America108(2011):18506\u201318511.","DOI":"10.1073\/pnas.1108644108"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.630792"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.110.079079"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/eraa419"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2009.07.002"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2001.00416.x"},{"key":"e_1_2_12_94_1","doi-asserted-by":"crossref","unstructured":"W. Z.Liu D. D.Kong X. X.Gu et\u00a0al. \u201cCytokinins Can Act as Suppressors of Nitric Oxide inArabidopsis \u201dProceedings of the National Academy of Sciences of the United States of America110(2013):1548\u20131553.","DOI":"10.1073\/pnas.1213235110"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.3390\/stresses1030014"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2017.12.005"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.15.00866"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erw259"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2020.02.002"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3040.2010.02194.x"},{"key":"e_1_2_12_101_1","doi-asserted-by":"crossref","unstructured":"M.Incarbone G.Bradamante F.Pruckner et\u00a0al. \u201cSalicylic Acid and RNA Interference Mediate Antiviral Immunity of Plant Stem Cells \u201dProceedings of the National Academy of Sciences of the United States of America120(2023):2302069120.","DOI":"10.1073\/pnas.2302069120"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.104.058719"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1111\/plb.13246"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb7360"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.659155"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004791"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2020.07.038"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00425-2"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2021.102074"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fcr.2024.109530"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1093\/aob\/mcf115"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jplph.2007.03.002"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.4161\/psb.29485"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erx371"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3040.2011.02324.x"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erx259"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envexpbot.2022.104796"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1080\/15592324.2018.1428517"},{"key":"e_1_2_12_119_1","first-page":"1350","article-title":"Stem Cell Fate in Hypoxic Root Apical Meristems Is Influenced by Phytoglobin Expression","volume":"71","author":"Mira M. M.","year":"2020","journal-title":"Journal of Experimental Botany"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-023-04246-5"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-023-04239-4"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.48130\/FR-2023-0005"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.110.160424"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241411637"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-9452(02)00159-0"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1093\/pcp\/pcn037"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/pce.12092"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11020372"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs\u20104117922\/v1"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.00521"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.3390\/agronomy8120276"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12298-018-0531-6"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2020.06.013"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2020.127416"},{"key":"e_1_2_12_135_1","first-page":"41","article-title":"Nitric Oxide Enhances Salt Tolerance Through Regulating Antioxidant Enzyme Activity and Nutrient Uptake in Pea","volume":"44","author":"Dadasoglu E.","year":"2021","journal-title":"Legume Research"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232213841"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-022-04015-w"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.15.00030"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1111\/jipb.13212"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.07.29.454319"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.17023"},{"key":"e_1_2_12_142_1","doi-asserted-by":"crossref","unstructured":"A. B.Kunkowska F.Fontana F.Betti et\u00a0al. \u201cTarget of Rapamycin Signaling Couples Energy to Oxygen Sensing to Modulate Hypoxic Gene Expression inArabidopsis \u201dProceedings of the National Academy of Sciences of the United States of America120(2023):2212474120.","DOI":"10.1073\/pnas.2212474120"}],"container-title":["BioEssays"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bies.70048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T07:51:14Z","timestamp":1758613874000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bies.70048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":141,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/bies.70048"],"URL":"https:\/\/doi.org\/10.1002\/bies.70048","archive":["Portico"],"relation":{},"ISSN":["0265-9247","1521-1878"],"issn-type":[{"value":"0265-9247","type":"print"},{"value":"1521-1878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"2024-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70048"}}