{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:21:17Z","timestamp":1791184877379,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,12,22]],"date-time":"2009-12-22T00:00:00Z","timestamp":1261440000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biometrical J"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We extend the Dahlberg and Wang (<jats:italic>Biometrics<\/jats:italic>2007,<jats:italic>63<\/jats:italic>, 1237\u20131244) proportional hazards (PH) cure model for the analysis of time\u2010to\u2010event data that is subject to a cure rate with masked event to a setting where the PH assumption does not hold. Assuming an accelerated failure time (AFT) model with unspecified error distribution for the time to the event of interest, we propose rank\u2010based estimating equations for the model parameters and use a generalization of the EM algorithm for parameter estimation. Applying our proposed AFT model to the same motivating breast cancer dataset as Dahlberg and Wang (<jats:italic>Biometrics<\/jats:italic>2007,<jats:italic>63<\/jats:italic>, 1237\u20131244), our results are more intuitive for the treatment arm in which the PH assumption may be violated. We also conduct a simulation study to evaluate the performance of the proposed method.<\/jats:p>","DOI":"10.1002\/bimj.200800244","type":"journal-article","created":{"date-parts":[[2009,12,22]],"date-time":"2009-12-22T17:22:32Z","timestamp":1261502552000},"page":"932-945","source":"Crossref","is-referenced-by-count":3,"title":["An Accelerated Failure Time Mixture Cure Model with Masked Event"],"prefix":"10.1002","volume":"51","author":[{"given":"Jenny J.","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,12,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1952.10501187"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djg119"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/91.3.543"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1541-0420.2007.00811.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.11.064"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.2517-6161.1977.tb01600.x","article-title":"Maximum likelihood from incomplete data via the EM algorithm","volume":"39","author":"Dempster A. 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Ph.D. Thesis Harvard University."}],"container-title":["Biometrical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbimj.200800244","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bimj.200800244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T19:12:41Z","timestamp":1739646761000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bimj.200800244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.1002\/bimj.200800244"],"URL":"https:\/\/doi.org\/10.1002\/bimj.200800244","archive":["Portico"],"relation":{},"ISSN":["0323-3847","1521-4036"],"issn-type":[{"value":"0323-3847","type":"print"},{"value":"1521-4036","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}