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In this paper, we consider a semiparametric marginal mixture cure model for such data and propose to extend an existing generalized estimating equation approach by a new unbiased estimating equation for the regression parameters in the latency part of the model. The large sample properties of the regression effect estimators in both incidence and the latency parts are established. The finite sample properties of the estimators are studied in simulation studies. The proposed method is illustrated with a bone marrow transplantation data and a tonsil cancer data.<\/jats:p>","DOI":"10.1002\/bimj.201700114","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T15:23:57Z","timestamp":1525706637000},"page":"780-796","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Modeling clustered long\u2010term survivors using marginal mixture cure model"],"prefix":"10.1002","volume":"60","author":[{"given":"Yi","family":"Niu","sequence":"first","affiliation":[{"name":"School of Mathematical Sciences Dalian University of Technology Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixin","family":"Song","sequence":"additional","affiliation":[{"name":"School of Mathematical Sciences Dalian University of Technology Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Mathematical Sciences Dalian University of Technology Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7391-9788","authenticated-orcid":false,"given":"Yingwei","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences Queen's University Kingston ON Canada"},{"name":"Department of Mathematics and Statistics Queen's University Kingston ON Canada"},{"name":"Cancer Care and Epidemiology Cancer Research Institute Queen's University Kingston ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1952.10501187"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.2517-6161.1949.tb00020.x","article-title":"Maximum likelihood estimates of the proportion of patients cured by cancer therapy","volume":"11","author":"Boag J. 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