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This method possesses both the advantages of water\u2010bathing and hydrothermal methods for preparing high\u2010quality QDs with markedly reduced synthesis time, and better stability than a lone hydrothermal method. The QDs were characterized by transmission electronic microscopy and powder X\u2010ray diffraction and X\u2010ray photoelectron spectroscopy. The CdTe\u2013CdS QDs with core\u2013shell structure showed both enhanced fluorescence and better photo stability than nude CdTe QDs. After conjugating with antibody rabbit anti\u2010CEACAM8 (CD67), the as\u2010prepared <jats:sc>l<\/jats:sc>\u2010Cys capped CdTe\u2013CdS QDs were successfully used as fluorescent probes for the direct immuno\u2010labeling and imaging of HeLa cells. It was indicated that this kind of QD would have application potential in bio\u2010labeling and cell imaging. 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