{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T21:04:56Z","timestamp":1773867896115,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T00:00:00Z","timestamp":1369872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A novel, rapid and sensitive chemiluminescence (CL) method combined with flow\u2010injection (FI) has been established for the estimation of olanzapine. This method is based on the CL signal generated between N\u2010chlorosuccinimide and olanzapine in an alkaline medium in the presence of calcein and Zn(II). Under optimum conditions, the CL signal was proportional to the olanzapine concentration ranging from 1.0 \u00d7 10<jats:sup>\u201010<\/jats:sup> to 3.0 \u00d7 10<jats:sup>\u20107<\/jats:sup> g\/mL. The detection limit is 8.9 \u00d7 10<jats:sup>\u201011<\/jats:sup> g\/mL olanzapine (3\u03c3) and the relative standard deviation for 3.0 \u00d7 10<jats:sup>\u20109<\/jats:sup> g\/mL of olanzapine is 1.9% (<jats:italic>n<\/jats:italic> = 11). The current CL method was applied to determine olanzapine in pharmaceutical formulations and biological fluids with satisfactory results. The possible CL reaction mechanism is discussed briefly. Copyright \u00a9 2013 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bio.2531","type":"journal-article","created":{"date-parts":[[2013,5,31]],"date-time":"2013-05-31T01:21:44Z","timestamp":1369963304000},"page":"219-224","source":"Crossref","is-referenced-by-count":6,"title":["Flow\u2010injection chemiluminescence determination of olanzapine using N\u2010chlorosuccinimide\u2013calcein reaction sensitized by zinc (II)"],"prefix":"10.1002","volume":"29","author":[{"given":"Fang","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shihezi University  Shihezi Xinjiang 832003 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shihezi University  Shihezi Xinjiang 832003 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Cai","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shihezi University  Shihezi Xinjiang 832003 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/10401239909147064"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199753020-00007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2298\/CICEQ0902077B"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2298\/CICEQ0902095B"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2003.11.069"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.22.829"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1134\/S1061934810050084"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(00)00382-4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1081\/AL-120024338"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00706-008-0894-4"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1093\/jaoac\/91.6.1309","article-title":"Spectrofluorometric determination of olanzapine and fluphenazine hydrochloride in pharmaceutical preparations and human plasma using eosin: application to stability studies","volume":"91","author":"Belal F","year":"2008","journal-title":"J AOAC Int"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1081\/JLC-100101433"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jaoac\/93.3.811"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1093\/jaoac\/90.6.1573","article-title":"Patel nm. 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