{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:37:18Z","timestamp":1765294638786,"version":"build-2065373602"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T00:00:00Z","timestamp":1393200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Undergraduate Innovation Program","award":["201210759008"],"award-info":[{"award-number":["201210759008"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A novel post\u2010chemiluminescence (PCL) reaction was discovered when lercanidipine was injected into the CL reaction mixture of <jats:italic>N<\/jats:italic>\u2010chlorosuccinimide with alkaline eosin Y in the presence of cetyltrimethylammonium bromide (CTAB), where eosin Y was used as the CL reagent and CTAB as the surfactant. Based on this observation, a simple and highly sensitive PCL method combined with a flow injection (FI) technique was developed for the assay of lercanidipine. Under optimum conditions, the CL signal was linearly related to the concentration of lercanidipine in the range 7.0\u2009\u00d7\u200910<jats:sup>\u201010<\/jats:sup> to 3.0\u2009\u00d7\u200910<jats:sup>\u20106<\/jats:sup>\u2009g\/mL with a detection limit of 2.3\u2009\u00d7\u200910<jats:sup>\u201010<\/jats:sup>\u2009g\/mL (3\u03c3). The relative standard deviation (RSD) was 2.1% for 1.0\u2009\u00d7\u200910<jats:sup>\u20108<\/jats:sup>\u2009g\/mL lercanidipine (<jats:italic>n<\/jats:italic>\u2009=\u200913). The proposed method had been applied to the estimation of lercanidipine in tablets and human serum samples with satisfactory results. The possible CL mechanism is also discussed briefly. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bio.2651","type":"journal-article","created":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T13:32:52Z","timestamp":1393248772000},"page":"1008-1013","source":"Crossref","is-referenced-by-count":1,"title":["Flow injection chemiluminescence determination of lercanidipine based on <i>N<\/i>\u2010chlorosuccinimide\u2013eosin Y post\u2010chemiluminescence reaction"],"prefix":"10.1002","volume":"29","author":[{"given":"Guowei","family":"Wang","sequence":"first","affiliation":[{"name":"Key Laboratory for Chemical Materials of Xinjiang Uygur Autonomous Region, Engineering Center for Chemical Materials of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering Shihezi University  Xinjiang 832003 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory for Chemical Materials of Xinjiang Uygur Autonomous Region, Engineering Center for Chemical Materials of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering Shihezi University  Xinjiang 832003 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Gao","sequence":"additional","affiliation":[{"name":"Key Laboratory for Chemical Materials of Xinjiang Uygur Autonomous Region, Engineering Center for Chemical Materials of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering Shihezi University  Xinjiang 832003 People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200060050-00009"},{"key":"e_1_2_6_3_1","first-page":"15","article-title":"Pharmacological in vitro studies of the new 1,4\u2010dihydropyridine calcium antagonist lercanidipine","volume":"46","author":"Guarneri L","year":"1996","journal-title":"Arzneimittel\u2010Forschung"},{"key":"e_1_2_6_4_1","first-page":"832","article-title":"Pharma\u2010clinics. 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