{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:31:27Z","timestamp":1788870687858,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T00:00:00Z","timestamp":1411344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Science Foundation of China","doi-asserted-by":"crossref","award":["81201696"],"award-info":[{"award-number":["81201696"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Scientific Research Foundation of the Higher Education Institutions of Jiangsu Province","award":["11KJB320020"],"award-info":[{"award-number":["11KJB320020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A pH\u2010sensitive and double functional nanoprobe was designed and synthesized in a water\u2010soluble system using thioglycolic acid (TGA) and mercapto\u2010acetohydrazide (TGH) as the stabilizers. TGA is biocompatible because the carboxyl group is easily linked to biological macromolecules. At the same time, the hydrazide on TGH reacts with the aldehyde on poly(ethylene glycol) (PEG) and forms a hydrazone bond. The hydrazone bond ruptured at specific pH values and exhibited pH\u2010stimuli\u2010responsive characteristics. As an optical imaging probe, the PEG\u2013TGA\/TGH\u2010capped CdTe quantum dots (QDs) had high quality, with a fluorescence efficiency of 25\u201330%, and remained stable for at least five months. This pH\u2010responsive factor can be used for the effective release of CdTe QDs under the acidic interstitial extracellular environment of tumor cells. This allows the prepared pH\u2010stimuli\u2010responsive nanoprobes to show fluorescence signals for use in cancer cell imaging. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bio.2770","type":"journal-article","created":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T03:14:22Z","timestamp":1411355662000},"page":"519-525","source":"Crossref","is-referenced-by-count":6,"title":["Preparation of pH\u2010stimuli\u2010responsive PEG\u2013TGA\/TGH\u2010capped CdTe QDs and their application in cell labeling"],"prefix":"10.1002","volume":"30","author":[{"given":"Yan","family":"Du","sequence":"first","affiliation":[{"name":"Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy Xuzhou Medical College  Xuzhou Jiangsu 221004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongzhi","family":"Yang","sequence":"additional","affiliation":[{"name":"Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy Xuzhou Medical College  Xuzhou Jiangsu 221004 China"},{"name":"Department of Pharmaceutical Analysis Xuzhou Medical College  Xuzhou Jiangsu 221004 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