{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:54:04Z","timestamp":1791330844098,"version":"4.3.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,11,5]],"date-time":"2015-11-05T00:00:00Z","timestamp":1446681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A rapid, simple and sensitive label\u2010free fluorescence method was developed for the determination of trace amounts of an important drug, heparin. This new method was based on water\u2010soluble glutathione\u2010capped CdTe quantum dots (CdTe QDs) as the luminescent probe. CdTe QDs were prepared according to the published protocol and the sizes of these nanoparticles were verified through transmission electron microscopy (TEM), X\u2010ray diffraction (XRD) and dynamic light scattering (DLS) with an average particle size of about 7\u2009nm. The fluorescence intensity of glutathione\u2010capped CdTe QDs increased with increasing heparin concentration. These changes were followed as the analytical signal. Effective variables such as pH, QD concentration and incubation time were optimized. At the optimum conditions, with this optical method, heparin could be measured within the range 10.0\u2013200.0\u2009ng\u2009mL<jats:sup>\u22121<\/jats:sup> with a low limit of detection, 2.0\u2009ng\u2009mL<jats:sup>\u22121<\/jats:sup>. The constructed fluorescence sensor was also applied successfully for the determination of heparin in human serum. Copyright \u00a9 2015 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bio.3058","type":"journal-article","created":{"date-parts":[[2015,11,5]],"date-time":"2015-11-05T22:22:41Z","timestamp":1446762161000},"page":"958-964","source":"Crossref","is-referenced-by-count":24,"title":["A simple and sensitive label\u2010free fluorescence sensing of heparin based on Cdte quantum dots"],"prefix":"10.1002","volume":"31","author":[{"given":"B.","family":"Rezaei","sequence":"first","affiliation":[{"name":"Department of Chemistry Isfahan University of Technology  Isfahan 84156\u201083111 Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Shahshahanipour","sequence":"additional","affiliation":[{"name":"Department of Chemistry Isfahan University of Technology  Isfahan 84156\u201083111 Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali A.","family":"Ensafi","sequence":"additional","affiliation":[{"name":"Department of Chemistry Isfahan University of Technology  Isfahan 84156\u201083111 Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/b819896a"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.4314\/bcse.v22i2.61277"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2005.03.014"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1039\/c0cc05094f"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1191\/0267659103pf672oa"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2011.12.051"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200802074"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10812-013-9728-1"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2an35176e"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2012.12.007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"5122","DOI":"10.1016\/S1452-3981(23)19608-8","article-title":"Study on heparin determination using cathodic stripping voltammetry","volume":"7","author":"Piech R","year":"2012","journal-title":"Int J Electrochem Sci"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2012.09.019"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10337-013-2526-3"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2012.02.008"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2007.11.014"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1994.00420010073009"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/s8042043"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2013.12.009"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2015.01.053"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2013.11.050"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1366\/12-06948"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1039\/b404498n"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2an35328h"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1166\/sam.2012.1326"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1556-276X-8-253"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200600342"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/cm034081k"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2008.09.009"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac062060e"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/bio.2862"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP7Z9KBFINVGYF"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-013-9884-4"}],"container-title":["Luminescence"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbio.3058","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bio.3058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T14:17:01Z","timestamp":1759933021000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bio.3058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,5]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["10.1002\/bio.3058"],"URL":"https:\/\/doi.org\/10.1002\/bio.3058","archive":["Portico"],"relation":{},"ISSN":["1522-7235","1522-7243"],"issn-type":[{"value":"1522-7235","type":"print"},{"value":"1522-7243","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,5]]}}}