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Efficient F\u00f6rster resonance energy transfer (FRET) was observed to occur from BSA donor to CdTe acceptor as noted from reduction in the fluorescence of BSA and enhanced fluorescence from CdTe QDs. FRET parameters such as F\u00f6rster distance, spectral overlap integral, FRET rate constant and efficiency were determined. The quenching of BSA fluorescence in aqueous solution observed in the presence of CdTe QDs infers that fluorescence resonance energy transfer is primarily responsible for the quenching phenomenon. Bimolecular quenching constant <jats:styled-content>(<jats:italic>k<\/jats:italic><jats:sub><jats:italic>q<\/jats:italic><\/jats:sub>)<\/jats:styled-content> determined at different temperatures and the time\u2010resolved fluorescence data provide additional evidence for this. The binding stoichiometry and various thermodynamic parameters are evaluated by using the van \u2018t Hoff equation. The analysis of the results suggests that the interaction between BSA and CdTe QDs is entropy driven and hydrophobic forces play a key role in the interaction. Binding of QDs significantly shortened the fluorescence lifetime of BSA which is one of the hallmarks of FRET. The effect of size of the QDs on the FRET parameters are discussed in the light of FRET parameters obtained.<\/jats:p>","DOI":"10.1002\/bio.3231","type":"journal-article","created":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T07:43:15Z","timestamp":1478158995000},"page":"631-639","source":"Crossref","is-referenced-by-count":11,"title":["Interaction and energy transfer studies between bovine serum albumin and CdTe quantum dots conjugates: CdTe QDs as energy acceptor probes"],"prefix":"10.1002","volume":"32","author":[{"given":"M. G.","family":"Kotresh","sequence":"first","affiliation":[{"name":"Laser Spectroscopy Programme, Department of Physics and UGC\u2010Centre with Potential for Excellence (CPEPA) Karnatak University  Dharwad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. S.","family":"Inamdar","sequence":"additional","affiliation":[{"name":"Molecular Endocrinology and Development Laboratory, Department of Zoology, and UGC\u2010CPEPA Karnatak University  Dharwad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Shivkumar","sequence":"additional","affiliation":[{"name":"Laser Spectroscopy Programme, Department of Physics and UGC\u2010Centre with Potential for Excellence (CPEPA) Karnatak University  Dharwad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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