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In this study, we introduced a chemiluminescence (CL) method combined with microarray technology and a simple fabrication procedure to obtain a highly sensitive SUA probe based on a mesoporous metal oxide nanomaterial. The high\u2010throughput method was based on the generation of H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> from SUA by immobilized uricase and its measurement by a CL reaction catalyzed by mesoporous metal oxide nanomaterials. The CL probe was designed for SUA The linear range of the uric acid concentration was 0.6\u20139\u00a0\u03bcM and the detection limit was 0.1\u00a0\u03bcM. In comparison with the other SUA detection techniques, this method has the advantages of a low detection limit, high sensitivity and simplicity. A new sensitive high\u2010throughput approach was obtained for the determination of SUA.<\/jats:p>","DOI":"10.1002\/bio.3243","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T10:29:45Z","timestamp":1478773785000},"page":"730-734","source":"Crossref","is-referenced-by-count":3,"title":["A rapid and high\u2010throughput method for the determination of serum uric acid based on microarray technology and nanomaterial"],"prefix":"10.1002","volume":"32","author":[{"given":"Xiaohua","family":"Li","sequence":"first","affiliation":[{"name":"School of Chemistry and Environmental Engineering Shanxi Datong University  Datong Shanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunfeng","family":"Bai","sequence":"additional","affiliation":[{"name":"School of Chemistry and Environmental Engineering Shanxi Datong University  Datong Shanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Chemistry and Environmental Engineering Shanxi Datong University  Datong Shanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhujun","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shaanxi Normal University  China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000443283"},{"key":"e_1_2_6_3_1","first-page":"305","volume":"19","author":"Liang J.","year":"2015","journal-title":"Eur. 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