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Fluorescence enhancement efficiency of Cu NCs induced by <jats:sc>d<\/jats:sc>\u2010PA was linear, with the <jats:sc>d<\/jats:sc>\u2010PA concentration varying from 0.6\u201330\u00a0\u03bcg\u00a0ml<jats:sup>\u22121<\/jats:sup> (R<jats:sup>2<\/jats:sup>\u00a0=\u00a00.9952) and with a detection limit of 0.54\u00a0\u03bcg\u00a0ml<jats:sup>\u22121<\/jats:sup>. <jats:sc>d<\/jats:sc>\u2010PA content in human urine samples was detected with recoveries of 104.8\u2013112.99%. Fluorescence\u2010enhanced determination of <jats:sc>d<\/jats:sc>\u2010PA using Cu NCs was established for the first time and this rapid, easy and sensitive method should attract much attention for this application.<\/jats:p>","DOI":"10.1002\/bio.3672","type":"journal-article","created":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T00:39:42Z","timestamp":1562114382000},"page":"767-773","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Copper nanocluster\u2010based fluorescence enhanced determination of <scp>d<\/scp>\u2010penicillamine"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2283-0745","authenticated-orcid":false,"given":"Chunlei","family":"Ma","sequence":"first","affiliation":[{"name":"Chemistry and Chemical Engineering Department Taiyuan Institute of Technology  Taiyuan Shanxi 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