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SCN\u2010PMO possessed high selectivity and sensitivity towards Cu<jats:sup>2+<\/jats:sup> based on its specific fluorescence response. The detection limit of SCN\u2010PMO could be as low as 6.7 \u00d7 10<jats:sup>\u22127<\/jats:sup> M. Due to protection of the silica network, SCN chromophores in PMOs exhibited higher photostability and the resulting material possessed great repeatability. Additionally, the fluorescence changes of SCN\u2010PMO towards copper ions <jats:italic>in vivo<\/jats:italic> (zebrafish) showed that SCN\u2010PMO has potential application as a nanoprobe in biological fields.<\/jats:p>","DOI":"10.1002\/bio.4021","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T00:19:44Z","timestamp":1613089184000},"page":"951-957","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Highly selective fluorescence detection of Cu<sup>2+<\/sup> based on Schiff base functionalized periodic mesoporous organosilicas"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5609-4638","authenticated-orcid":false,"given":"Meng","family":"Gao","sequence":"first","affiliation":[{"name":"National Supercomputer Research Center of Advanced Materials, Advanced Materials Institute Qilu University of Technology (Shandong Academy of Sciences)  Jinan 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