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The utilized M\u2010sensor exhibited an emission fluorescence activity at 587\u2009nm upon excitation at 537\u2009nm. The developed method was based on the quenching effect of Mg<jats:sup>2+<\/jats:sup> ions on the fluorescence intensity of the M\u2010sensor with the above\u2010mentioned fluorescence features. Furthermore, the utilized M\u2010sensor was complexed with Mg<jats:sup>2+<\/jats:sup> ions in the molar ratio of 1:1 (Mg<jats:sup>2+<\/jats:sup> to M\u2010sensor) and the selectivity of M\u2010sensor toward Mg<jats:sup>2+<\/jats:sup> against other metals ions, and the reversibility and reusability of the sensor were studied and verified. After optimization of the fluorometric detection, the quenching effect was directly proportional to the increase in the concentration of Mg<jats:sup>2+<\/jats:sup> in the linear range 100\u2013600\u2009ng\u2009ml<jats:sup>\u22121<\/jats:sup> with a limit of detection value of 18\u2009ng\u2009ml<jats:sup>\u22121<\/jats:sup>. The fluorescence sensor was successfully applied with good recovery for the determination of Mg<jats:sup>2+<\/jats:sup> in water samples and different pharmaceutical samples (ampoules and suspension) without any interference from aluminium.<\/jats:p>","DOI":"10.1002\/bio.4193","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T01:44:41Z","timestamp":1642038281000},"page":"448-454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Spectrofluorimetric determination of magnesium ions in water, ampoule, and suspension samples using a fluorescent azothiazol\u2010benzenesulfonamide derivative"],"prefix":"10.1002","volume":"37","author":[{"given":"Zaki","family":"Badr","sequence":"first","affiliation":[{"name":"Chemistry Department, Faculty of Science Al\u2010Azhar University  Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3020-4966","authenticated-orcid":false,"given":"Mohamed A.","family":"Abdel\u2010Lateef","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy Al\u2010Azhar University  Assiut Branch Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassanien","family":"Gomaa","sequence":"additional","affiliation":[{"name":"Chemistry Department, Faculty of Science Al\u2010Azhar University  Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abdelmottaleb","sequence":"additional","affiliation":[{"name":"Chemistry Department, Faculty of Science Al\u2010Azhar University  Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Taher","sequence":"additional","affiliation":[{"name":"Chemistry Department, Faculty of Science Al\u2010Azhar University  Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jma.2020.02.025"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9NJ04536H"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.527788"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016058229972"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6JA90044E"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sna.2020.111949"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cemconres.2018.03.011"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2010.10.013"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016074714951"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2007.05.020"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)01209-7"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/b707225b"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymertesting.2017.01.023"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fuel.2018.09.108"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sab.2011.11.002"},{"key":"e_1_2_6_17_1","first-page":"5391","volume":"19","author":"Modarres\u2010Tehrani Z.","year":"2007","journal-title":"Asian J. 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