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NiO NPs were prepared using <jats:italic>Buddleja polystachya<\/jats:italic> Fresen leaf extract and Ni(NO<jats:sub>3<\/jats:sub>)<jats:sub>2<\/jats:sub>.6H<jats:sub>2<\/jats:sub>O as precursors. The C\u2010dots were synthesized from benzene\u20101,4\u2010diamine and citric acid. The cubic structure of the NiO NPs and NiO NPs@C\u2010dots was in phase with their average particle size distributions of 21.47\u2009\u00b1\u20090.56 and 21.61\u2009\u00b1\u20090.34\u2009nm, respectively. The surface morphology of the NiO NPs@C\u2010dots was characterized using field emission scanning electron microscopy and also revealed a large surface area, which is advantageous for the specified application. The X\u2010ray diffraction result indicated a cubic face wurtzite structure and the crystalline nature of the NiO NPs. Carbon\u2010doped compounds had no influence on the crystal structure of the NiO compound and no new peaks were observed. The antibacterial activity of a composite made up of NiO NPs@C\u2010dots was tested, as well as the antibacterial activities of compounds produced against human photogenic bacterial strains. Both NiO NPs and NiO NPs@C\u2010dots were found to be powerful against all bacterial strains, based on the bioassay results. NiO NPs and NiO@C\u2010dots appeared to display strong to inhibitory effects of 14\u201320\u2009mm and 17\u201323\u2009mm, respectively.<\/jats:p>","DOI":"10.1002\/bio.4241","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T07:36:04Z","timestamp":1648452964000},"page":"965-970","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Hybridization of nickel oxide nanoparticles with carbon dots and its application for antibacterial activities"],"prefix":"10.1002","volume":"37","author":[{"given":"Dugasa Jabesa","family":"Nemera","sequence":"first","affiliation":[{"name":"Department of Chemistry, College of Natural Sciences Jimma University  Jimma Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5638-1231","authenticated-orcid":false,"given":"Habtamu Fekadu","family":"Etefa","sequence":"additional","affiliation":[{"name":"Department of Physics, College of Natural and Computational Science Dambi Dollo University  Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6425-5120","authenticated-orcid":false,"given":"Vinod","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Physics, College of Natural and Computational Science Dambi Dollo University  Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4474-199X","authenticated-orcid":false,"given":"Francis Birhanu","family":"Dejene","sequence":"additional","affiliation":[{"name":"Department of Chemical and Physical Sciences Walter Sisulu University  Private Bag X1 Mthatha South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/b517131h"},{"key":"e_1_2_7_3_1","first-page":"3512145","volume":"16","author":"Din M. 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