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Therefore, the early detection of cancer cells can play a crucial role in enhancing the chances of a patient's survival. In this light, we present a nonfluorescent receptor used for the detection of Zn<jats:sup>2+<\/jats:sup> ion in MDA\u2010MB\u2010231 carcinoma cells that exhibits fluorescence turn\u2010on behaviour upon binding with the metal ion. In this work, the synthesis of 11,16\u2010bis(2,6\u2010difluorobenzene)\u20106,6,21,21\u2010tetramethyl\u2010<jats:italic>meta<\/jats:italic>\u2010benziporpho\u20106,21\u2010dimethene and its Zn<jats:sup>2+<\/jats:sup> chloride complex have been reported. The compounds were fully characterized using UV\u2013visible, nuclear magnetic resonance (NMR), infrared (IR) and mass spectrometry. Furthermore, the X\u2010ray polymorphs of a <jats:italic>meta<\/jats:italic>\u2010benziporphodimethene analogue were added. The study of its bioimaging applications in MDA\u2010MB\u2010231 breast cancer cells for the detection of Zn<jats:sup>2+<\/jats:sup> ions is reported.<\/jats:p>","DOI":"10.1002\/bio.4382","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T02:49:44Z","timestamp":1662518984000},"page":"1268-1274","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Structural characterization and bioimaging of Zn<sup>2+<\/sup> using <i>meta<\/i>\u2010benziporphodimethene analogue"],"prefix":"10.1002","volume":"38","author":[{"given":"Shikha","family":"Rana","sequence":"first","affiliation":[{"name":"Department of Applied Chemistry Delhi Technological University  Bawana Road Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"National Dope Testing Laboratory  New Delhi 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