{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T22:05:06Z","timestamp":1780351506028,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:00:00Z","timestamp":1672963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mercury (Hg<jats:sup>2+<\/jats:sup>) is a natural element present in foods such as fish, water and soil. Exposure to mercury leads to severe toxic effects on the nervous, digestive, and immune systems. Here, a novel, green, and environmentally friendly fluorescent probe decorated with cysteine\/MnO<jats:sub>2<\/jats:sub> quantum dots (Cys@MnO<jats:sub>2<\/jats:sub> QDs) was synthesized. This synthesis was carried out using a simple ultrasound technique with the aid of cysteine for fabricating Cys@MnO<jats:sub>2<\/jats:sub> QDs to estimate Hg levels in fish and water samples. In this morphological study, Cys@MnO<jats:sub>2<\/jats:sub> QDs were fully characterized using high\u2010resolution transmission electron microscopy, zeta potential analysis, fluorescence, ultraviolet\u2013visible and infrared spectroscopy. The fluorescence of the synthesized Cys@MnO<jats:sub>2<\/jats:sub> QDs was significantly quenched by gradually increasing the Hg(II) concentration. The quenching mechanism based on the Hg\u2013S bonds strengthened the utility of the Cys@MnO<jats:sub>2<\/jats:sub> QDs as a novel luminescent nanoprobe. The estimation of Hg was linear in the concentration range 0.7\u2013100.0\u2009ng\u2009mL<jats:sup>\u22121<\/jats:sup> with a limit of quantitation equal to 0.30\u2009ng\u2009mL<jats:sup>\u22121<\/jats:sup>. The Cys@MnO<jats:sub>2<\/jats:sub> QDs are fluorescent probes with various benefits such as speed, ease of use, cost\u2010 effective, and being environmentally friendly; they are easily applied in food manufacturing and for public health improvement.<\/jats:p>","DOI":"10.1002\/bio.4431","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T09:27:19Z","timestamp":1672306039000},"page":"145-151","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Ultrasensitive green spectrofluorimetric approach for quantification of Hg(II) in environmental samples (water and fish samples) using cysteine@MnO<sub>2<\/sub> dots"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6410-3725","authenticated-orcid":false,"given":"Baher I.","family":"Salman","sequence":"first","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Al\u2010Azhar University  Assiut branch Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasser F.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Al\u2010Azhar University  Assiut branch Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa F. B.","family":"Ali","sequence":"additional","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Assiut University  Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hany A.","family":"Batakoushy","sequence":"additional","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Menoufia University  Shebin Elkom Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/460508"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3961\/jpmph.2012.45.6.353"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA01980A"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.0c05102"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(99)00742-4"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.17221\/577\/2013-CJFS"},{"key":"e_1_2_6_8_1","first-page":"1","volume":"51","author":"Gao C.","year":"2013","journal-title":"TrAC"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2007.03.014"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/elan.200704044"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2017.08.028"},{"key":"e_1_2_6_12_1","first-page":"215","volume":"75","author":"Xia Y.","year":"2007","journal-title":"Talanta"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00604-007-0816-x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2017.06.058"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00604-018-2994-0"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4RA06683A"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2RA02241A"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2014.06.054"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/am301136q"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2021.105982"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA24971J"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/bio.4291"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13065-022-00849-3"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2008.01.008"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13065-022-00894-y"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2005.02.037"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/00032719.2020.1759618"}],"container-title":["Luminescence"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bio.4431","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bio.4431","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bio.4431","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T11:39:08Z","timestamp":1759923548000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bio.4431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,6]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1002\/bio.4431"],"URL":"https:\/\/doi.org\/10.1002\/bio.4431","archive":["Portico"],"relation":{},"ISSN":["1522-7235","1522-7243"],"issn-type":[{"value":"1522-7235","type":"print"},{"value":"1522-7243","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,6]]},"assertion":[{"value":"2022-10-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}