{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:08:19Z","timestamp":1759972099905,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T00:00:00Z","timestamp":1676678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2020J01637"],"award-info":[{"award-number":["2020J01637"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\"><jats:italic>Helicobacter pylori<\/jats:italic><\/jats:styled-content> is closely linked to many gastric diseases such as gastric ulcers and duodenal ulcers. Therefore, biosensing <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> has attracted wide attention from both scientists and clinicians. Here, we proposed an electrochemiluminescence (ECL)\u2010based platform that could sensitively detect <jats:styled-content style=\"fixed-case\"><jats:italic>H. pylori<\/jats:italic><\/jats:styled-content> DNA. In this platform, a novel target\u2010cycling synchronized rolling circle amplification was used for signal amplification. Silver nanoclusters (Ag NCs) were synthesized on the circle DNA products, embedding them with the ability to catalyze the electrochemical reduction of K<jats:sub>2<\/jats:sub>S<jats:sub>2<\/jats:sub>O<jats:sub>8<\/jats:sub>, in turn resulting in rapid consumption of the ECL co\u2010reactant near the working electrode, and leading to a decrease in the ECL emission intensity. In addition to its excellent stability and selectivity, the proposed strategy had a low detection limit of 10 pM, an indication that it can be beneficially applied to test biosamples. Furthermore, a biosensing chip was designed to improve the throughput and shed new light on large\u2010scale clinical biosensing applications.<\/jats:p>","DOI":"10.1002\/bio.4457","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T21:34:51Z","timestamp":1675892091000},"page":"334-340","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Target\u2010cycling synchronized rolling circle amplification strategy for biosensing <scp><i>Helicobacter pylori<\/i><\/scp> DNA"],"prefix":"10.1002","volume":"38","author":[{"given":"Xiaorong","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Health Inspection and Quarantine, School of Public Health Fujian Medical University  Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Health Inspection and Quarantine, School of Public Health Fujian Medical University  Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongzhao","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Health Inspection and Quarantine, School of Public Health Fujian Medical University  Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirui","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Health Inspection and Quarantine, School of Public Health Fujian Medical University  Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sijia","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Health Inspection and Quarantine, School of Public Health Fujian Medical University  Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanlan","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Chemistry, Key Laboratory of Analysis and Detecting Technology, Food Safety MOE Fuzhou University  Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8138-9537","authenticated-orcid":false,"given":"Shanwen","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Health Inspection and Quarantine, School of Public Health Fujian Medical University  Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2011.165605"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2012.201475"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.20964\/2017.04.16"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bio.3493"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2016.07.061"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2020.128049"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2011.04.010"},{"key":"e_1_2_9_9_1","first-page":"10","volume":"24","author":"Yan W. 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