{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:32:36Z","timestamp":1786977156320,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A simple and facile microwave\u2010assisted method was developed for the synthesis of highly fluorescent nitrogen\u2010doped carbon quantum dots (N\u2010CQDs) using sucrose and urea. The produced quantum dots exhibited a strong emission band at 376\u2009nm after excitation at 216\u2009nm with quantum yield of 0.57. The as\u2010prepared N\u2010CQDs were characterized using Fourier\u2010transform infrared (FTIR) spectroscopy, transmission electron microscopy (TEM) images, and ultraviolet\u2010visible (UV\u2010visible) spectra. The average particle size was 7.7\u00a0nm. It was found that torsemide (TRS) caused an obvious quenching of the fluorescent N\u2010CQDs; so, they were used for its spectrofluorometric estimation. An excellent linear correlation was found between the fluorescence quenching of N\u2010CQDs and the concentration of the drug in the range of 0.10 to 1.0\u00a0\u03bcg\/mL with limit of quantitation (LOQ) of 0.08\u2009\u03bcg\/mL and limit of detection (LOD) of 0.027\u2009\u03bcg\/mL. The method was successfully applied for the assay of the drug in its commercial tablets and spiked human plasma samples, and the results obtained were satisfactory. Complex GAPI was used for greenness assessment of the analytical procedures and the pre\u2010analysis steps. Interference likely to be introduced from co\u2010administered drugs was also studied.<\/jats:p>","DOI":"10.1002\/bio.4710","type":"journal-article","created":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T03:48:11Z","timestamp":1710388091000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Highly fluorescent nitrogen\u2010doped carbon quantum dots prepared using sucrose and urea: Green synthesis, characterization, and use for determination of torsemide in its tablets and plasma samples"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5420-4971","authenticated-orcid":false,"given":"Mona H.","family":"Abo Zaid","sequence":"first","affiliation":[{"name":"Pharmaceutical Chemistry Department, Faculty of Pharmacy Delta University for Science and Technology  Gamasa Egypt"},{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Suez Canal University  Ismailia Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahed","family":"El\u2010Enany","sequence":"additional","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Mansoura University  Mansoura Egypt"},{"name":"Pharmaceutical Chemistry Department, Faculty of Pharmacy New Mansoura University  New Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aziza E.","family":"Mostafa","sequence":"additional","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Suez Canal University  Ismailia Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghada M.","family":"Hadad","sequence":"additional","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Suez Canal University  Ismailia Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fathalla","family":"Belal","sequence":"additional","affiliation":[{"name":"Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy Mansoura University  Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9AY02696G"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0DT01004A"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtchem.2019.03.001"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9TC01640F"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612829666221103124856"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10895-023-03276-2"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13065-023-00937-y"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10895-023-03217-z"},{"key":"e_1_2_9_10_1","first-page":"149","volume":"9","author":"Hinge M.","year":"2019","journal-title":"J. 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