{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T01:09:28Z","timestamp":1759972168912,"version":"build-2065373602"},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2001,7,31]],"date-time":"2001-07-31T00:00:00Z","timestamp":996537600000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2001,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We investigated the effects of carbon disulphide (CS<jats:sub>2<\/jats:sub>) on hydroxyl radical generation using the phenanthroline chemiluminescence system. The influence of CS<jats:sub>2<\/jats:sub> on the phenanthroline chemiluminescence system without CuSO<jats:sub>4<\/jats:sub> and vitamin C were tested. The results showed that CS<jats:sub>2<\/jats:sub> enhanced the emission intensity of chemiluminescence and advanced the peak time of the chemiluminescence. There was a dose\u2013effect relationship between CS<jats:sub>2<\/jats:sub> concentrations (0\u2013160\u2005mg\/ml) and chemiluminescence peak intensity (<jats:italic>r<\/jats:italic>\u2005=\u20050.955, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2005=\u20050.913, <jats:italic>p<\/jats:italic>\u2005=\u20050.003), as well as CS<jats:sub>2<\/jats:sub> concentrations and peak time (<jats:italic>r<\/jats:italic>\u2005=\u2005\u22120.927, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2005=\u20050.860, <jats:italic>p<\/jats:italic>\u2005=\u20050.008). The enhanced chemiluminescence induced by CS<jats:sub>2<\/jats:sub> could be inhibited by thiourea, and the inhibition rate gradually deceased along with increasing CS<jats:sub>2<\/jats:sub> concentration (<jats:italic>r<\/jats:italic>\u2005=\u2005\u22120.816, <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2005=\u20050.666, <jats:italic>p<\/jats:italic>\u2005=\u20050.048). When the system was free of CuSO<jats:sub>4<\/jats:sub> and vitamin C, CS<jats:sub>2<\/jats:sub> also induced the emission of chemiluminescence intensity. We conclude from these results that CS<jats:sub>2<\/jats:sub> can induce the phenanthroline chemiluminescence system to generate hydroxyl radicals and advance the peak time, and that thiourea can inhibit the effect. The mechanism may be explained by a catalytic effect of CS<jats:sub>2<\/jats:sub> directly on H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bio.656","type":"journal-article","created":{"date-parts":[[2005,1,26]],"date-time":"2005-01-26T02:55:59Z","timestamp":1106708159000},"page":"291-293","source":"Crossref","is-referenced-by-count":2,"title":["Influence of carbon disulphide on hydroxyl radicals in the phenanthroline chemiluminescence system"],"prefix":"10.1002","volume":"16","author":[{"given":"Le","family":"Jian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huai","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,7,31]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"223","volume-title":"Free Radical Medicine","author":"Chen Y","year":"1991"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.3109\/10408448309128255"},{"key":"e_1_2_1_4_2","series-title":"Free Radicals in Biology","first-page":"1","author":"Accst SD","year":"1982"},{"key":"e_1_2_1_5_2","first-page":"136","article-title":"A chemiluminescence system to generate and scavenge OH","volume":"19","author":"Che JW","year":"1992","journal-title":"Biochem. Biophys. Dev."},{"issue":"6","key":"e_1_2_1_6_2","first-page":"68","article-title":"The establishment of o\u2010phenanthroline chemiluminescent system for measuring OH radical","volume":"18","author":"Fan XB","year":"1998","journal-title":"Basic Med. Sci. Clin."},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004200000169"},{"key":"e_1_2_1_8_2","first-page":"416","article-title":"The effect of carbon disulfide (CS2) on the level of lipid peroxidation and glutathione","volume":"19","author":"Chang YX","year":"1987","journal-title":"J. Beijing Med. Univ."},{"key":"e_1_2_1_9_2","first-page":"245","article-title":"Lipid peroxidation effect of carbon disulfide on cardiovascular system","volume":"11","author":"Zhang WC","year":"1992","journal-title":"Chin. J. Publ. Health"}],"container-title":["Luminescence"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbio.656","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bio.656","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:44:42Z","timestamp":1759952682000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bio.656"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["10.1002\/bio.656"],"URL":"https:\/\/doi.org\/10.1002\/bio.656","archive":["Portico"],"relation":{},"ISSN":["1522-7235","1522-7243"],"issn-type":[{"type":"print","value":"1522-7235"},{"type":"electronic","value":"1522-7243"}],"subject":[],"published":{"date-parts":[[2001,7]]}}}