{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:11:03Z","timestamp":1785528663143,"version":"3.56.0"},"reference-count":57,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This work implies the preparation, structural and fluorescent characterization, and application of the 1,8\u2010naphthalimide\u2010based fluorescent probe for H\n                    <jats:sub>2<\/jats:sub>\n                    S detection in human blood serum. The mechanism of fluorescent detection of H\n                    <jats:sub>2<\/jats:sub>\n                    S is based on the reduction of the azide group, as the chemical reactive site, in the fluorescent probe structure, to the amino group. Compound\n                    <jats:bold>2<\/jats:bold>\n                    possesses another important structural motif, ethanolamine moiety, which modulates physicochemical properties. The synthetic pathway for the preparation of compound\n                    <jats:bold>2<\/jats:bold>\n                    is consisted of two reaction steps, and the target compound was prepared with a yield of 56%. The prepared compound\n                    <jats:bold>2<\/jats:bold>\n                    was characterized using\n                    <jats:sup>1<\/jats:sup>\n                    H and\n                    <jats:sup>13<\/jats:sup>\n                    C NMR spectroscopy and elemental analysis. During the fluorescence spectra measurements, several influences on fluorescence intensity were investigated, including pH, time dependence, selective response, and influence of H\n                    <jats:sub>2<\/jats:sub>\n                    S concentration. The detection limit was calculated, which was 0.16\u2009\u03bcmol\u2009L\n                    <jats:sup>\u22121<\/jats:sup>\n                    . For examination of the application of compound\n                    <jats:bold>2<\/jats:bold>\n                    for H\n                    <jats:sub>2<\/jats:sub>\n                    S detection in real samples, compound\n                    <jats:bold>2<\/jats:bold>\n                    was successfully applied for H\n                    <jats:sub>2<\/jats:sub>\n                    S detection in human blood serum. The concentration of H\n                    <jats:sub>2<\/jats:sub>\n                    S in the human serum sample was 16.2\u2009\u03bcmol\u2009L\n                    <jats:sup>\u22121<\/jats:sup>\n                    .The accuracy of H\n                    <jats:sub>2<\/jats:sub>\n                    S determination in human blood serum samples is confirmed by the standard addition method and UV\u2010Vis spectrophotometry method using methylene blue.\n                  <\/jats:p>","DOI":"10.1002\/bio.70295","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T01:30:04Z","timestamp":1755653404000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Development and Application of a 1,8\u2010Naphthalimide\u2010Based Fluorescent Probe for Sensitive Detection of Hydrogen Sulfide in Human Blood Serum"],"prefix":"10.1002","volume":"40","author":[{"given":"Aleksandar","family":"Sz\u00e9chenyi","sequence":"first","affiliation":[{"name":"Department of Chemistry Josip Juraj Strossmayer University of Osijek  Osijek Croatia"},{"name":"Green Chemistry Research Group, J\u00e1nos Szent\u00e1gothai Research Centre University of P\u00e9cs  P\u00e9cs Hungary"},{"name":"Institute of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy University of P\u00e9cs  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirela","family":"Samard\u017ei\u0107","sequence":"additional","affiliation":[{"name":"Department of Chemistry Josip Juraj Strossmayer University of Osijek  Osijek Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateja","family":"Budeti\u0107","sequence":"additional","affiliation":[{"name":"Department of Chemistry Josip Juraj Strossmayer University of Osijek  Osijek Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4964-7721","authenticated-orcid":false,"given":"Ines","family":"Drenjan\u010devi\u0107","sequence":"additional","affiliation":[{"name":"Department of Physiology and Immunology, Faculty of Medicine Osijek J. 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