{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T05:19:58Z","timestamp":1787635198898,"version":"build-2736575974"},"reference-count":53,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["22ZR1460900"],"award-info":[{"award-number":["22ZR1460900"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Luminescence"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Propranolol hydrochloride (PRO\u2010HCl), a nonselective\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2010adrenergic receptor blocker, is widely utilized in the treatment of various medical conditions including hypertension, angina pectoris, cardiac arrhythmias, migraine prophylaxis, and certain anxiety disorders. In this study, we developed a simple, convenient, and sensitive quantitative detection method for PRO\u2010HCl in aqueous environments, based on the fluorescence generated from the reaction between Cadmium sulfide quantum dots (CdS QDs) and PRO\u2010HCl at room temperature. The synthesized CdS QDs were thoroughly characterized using fluorescence spectroscopy, UV\u2013Vis spectrophotometry, and Fourier\u2010transform infrared spectroscopy (FTIR) to investigate their optical and structural properties. Our experimental results demonstrated a significant enhancement in the fluorescence intensity of CdS QDs in the presence of low concentrations of propranolol hydrochloride. Through systematic optimization of experimental conditions, we established a linear relationship between the fluorescence intensity of CdS QDs and PRO\u2010HCl concentration within the range of 0.002\u20138\u2009mg\u00b7L\n                    <jats:sup>\u22121<\/jats:sup>\n                    . The linear regression equation was determined to be\n                    <jats:italic>Y<\/jats:italic>\n                    \u2009=\u20090.6479\n                    <jats:italic>X<\/jats:italic>\n                    \u2009+\u20090.0685 with a correlation coefficient (\n                    <jats:italic>R<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    ) of 0.9858, and the detection limit was found to be 0.002\u2009mg\u00b7L\n                    <jats:sup>\u22121<\/jats:sup>\n                    . Furthermore, we investigated the potential reaction mechanism between CdS QDs and PRO\u2010HCl. To validate the practical application of CdS QDs, the proposed method was successfully employed for the determination of PRO\u2010HCl in spiked environmental water samples, demonstrating the effectiveness and reliability of the CdS QDs\u2010based detection system.\n                  <\/jats:p>","DOI":"10.1002\/bio.70596","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T13:13:06Z","timestamp":1786021986000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fluorescence Analysis of Propranolol Hydrochloride Using Mercaptoacetic Acid\u2010Capped Cadmium Sulfide Quantum Dots and Mechanism of Reaction Process"],"prefix":"10.1002","volume":"41","author":[{"given":"Yilei","family":"Chen","sequence":"first","affiliation":[{"name":"School of Environment and Chemical Engineering Shanghai University  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5542-5077","authenticated-orcid":false,"given":"Xiaolin","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Environment and Chemical Engineering Shanghai University  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zitong","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Environment and Chemical Engineering Shanghai University  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyang","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Environment and Chemical Engineering Shanghai University  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4756-2540","authenticated-orcid":false,"given":"Shuyu","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Environment and Chemical Engineering Shanghai University  Shanghai People's Republic of China"},{"name":"Zhejiang University, Hangzhou  Hangzhou Zhejiang People's Republic of China"},{"name":"Shanghai Zhixi Technology Co. Ltd  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingjiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Zhejiang University, Hangzhou  Hangzhou Zhejiang People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2020.113164"},{"key":"e_1_2_10_3_1","first-page":"287","volume-title":"Profiles of Drug Substances, Excipients and Related Methodology","author":"Al\u2010Majed A. 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