{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:24:41Z","timestamp":1792020281448,"version":"4.4.0"},"reference-count":154,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioFactors"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Over the past years, several studies have found that foods rich in polyphenols protect against age\u2010related disease, such as atherosclerosis, cardiovascular disease, cancer, arthritis, cataracts, osteoporosis, type 2 diabetes (T2D), hypertension and Alzheimer's disease. Resveratrol and pterostilbene, the polyphenol found in grape and blueberries, have beneficial effects as anti\u2010aging compounds through modulating the hallmarks of aging, including oxidative damage, inflammation, telomere attrition and cell senescence. In this review, we discuss the relationship between resveratrol and pterostilbene and possible aging biomarker, including oxidative stress, inflammation, and high\u2010calorie diets. Moreover, we also discuss the positive effect of resveratrol and pterostilbene on lifespan, aged\u2010related disease, and health maintenance. Furthermore, we summarize a variety of important mechanisms modulated by resveratrol and pterostilbene possibly involved in attenuating age\u2010associated disorders. Overall, we describe resveratrol and pterostilbene potential for prevention or treatment of several age\u2010related diseases by modulating age\u2010related mechanisms. \u00a9 2017 BioFactors, 44(1):69\u201382, 2018<\/jats:p>","DOI":"10.1002\/biof.1400","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T04:52:55Z","timestamp":1512535975000},"page":"69-82","source":"Crossref","is-referenced-by-count":321,"title":["Effect of resveratrol and pterostilbene on aging and longevity"],"prefix":"10.1002","volume":"44","author":[{"given":"Yi\u2010Rong","family":"Li","sequence":"first","affiliation":[{"name":"Changhua Christian Hospital Thoracic Medicine Research center Changhua 50006 Taiwan, Republic of China"},{"name":"Institute of Biomedical Science National Chung\u2010Hsing University Taichung 40227 Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6167-0660","authenticated-orcid":false,"given":"Shiming","family":"Li","sequence":"additional","affiliation":[{"name":"Hubei Key Laboratory of Processing and Application of Catalytic Materials, College of Chemical Engineering Huanggang Normal University Huanggang Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1464-0231","authenticated-orcid":false,"given":"Chi\u2010Chien","family":"Lin","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Science National Chung\u2010Hsing University Taichung 40227 Taiwan, Republic of China"},{"name":"Department of Health and Nutrition Asia University Taichung 41354 Taiwan, Republic of China"},{"name":"Department of Medical Research China Medical University Hospital Taichung 40402 Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.05.039"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2016.07.017"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","DOI":"10.3390\/molecules22081329","article-title":"Significance of resveratrol in clinical management of chronic diseases","volume":"22","author":"Wahab A.","year":"2017","journal-title":"Molecules"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/03602532.2015.1102933"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/340520"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9175806"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20160897"},{"key":"e_1_2_8_9_1","article-title":"Beyond diabetes: does obesity\u2010induced oxidative stress drive the aging process?","volume":"5","author":"Salmon A. B.","year":"2016","journal-title":"Antioxidants (Basel)"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2016.6802"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.patbio.2015.07.008"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2015.01.002"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/404680"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.6.20.4815"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-014-1012-1"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12315"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2011.08.008"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0115341"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114511000316"},{"key":"e_1_2_8_20_1","first-page":"577","article-title":"Resveratrol protects against peroxynitrite\u2010induced thiol oxidation in blood platelets","volume":"9","author":"Olas B.","year":"2004","journal-title":"Cell Mol Biol Lett"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glq080"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2012.05.002"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2014.530"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt102"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.2203\/dose-response.09-015.Mukherjee"},{"key":"e_1_2_8_26_1","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1042\/BST0351156","article-title":"Resveratrol as an antioxidant and pro\u2010oxidant agent: mechanisms and clinical implications","volume":"35","author":"la Lastra C. A.","year":"2007","journal-title":"Biochem Soc Trans"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-010-9286-3"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2015.02.004"},{"key":"e_1_2_8_29_1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.neurobiolaging.2016.04.007","article-title":"Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice","volume":"44","author":"Jeong S. I.","year":"2016","journal-title":"Neurobiol Aging"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8379539"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2013.03.011"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867311320100009"},{"key":"e_1_2_8_33_1","first-page":"475","article-title":"Resveratrol more effectively than quercetin reduces endothelium degeneration and level of necrosis factor \u03b1 in patients with coronary artery disease","volume":"69","author":"Chekalina N. I.","year":"2016","journal-title":"Wiad Lek"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2011.03.015"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034289"},{"key":"e_1_2_8_36_1","first-page":"1","article-title":"Effects of resveratrol supplementation on risk factors of non\u2010communicable diseases: a meta\u2010analysis of randomized controlled trials","author":"Guo X. F.","year":"2017","journal-title":"Crit Rev Food Sci Nutr"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.10.002"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2011.06.010"},{"key":"e_1_2_8_39_1","article-title":"Caloric restriction mimetics slow aging of neuromuscular synapses and muscle fibers","author":"Stockinger J.","year":"2017","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874609808666150122153151"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874609811104010001"},{"key":"e_1_2_8_42_1","first-page":"4310","article-title":"Resveratrol\u2010induced augmentation of telomerase activity delays senescence of endothelial progenitor cells","volume":"124","author":"Wang X. B.","year":"2011","journal-title":"Chin Med J (Engl)"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.3580"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-13-238"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2016.04.048"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2017.01.005"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep19408"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13948"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2015.03.027"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2017.06.015"},{"key":"e_1_2_8_51_1","first-page":"8","article-title":"Suppression of nitric oxide production and cardiovascular risk factors in healthy seniors and hypercholesterolemic subjects by a combination of polyphenols and vitamins","volume":"5","author":"Qureshi A. A.","year":"2012","journal-title":"J Clin Exp Cardiolog"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2014.03.015"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf304487v"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2014.10.018"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16716"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2017.02.015"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2015.10.002"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2017.05.022"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2016.08.005"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.115.223909"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6FO01216G"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.237.183"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.03.038"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/575482"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01960"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2006.06.038"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2007.07.007"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-011-9332-3"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.100474"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2005.12.038"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1836"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.06.011"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glq178"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gls070"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.6.7.16499"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9728.2004.00097.x"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028855"},{"key":"e_1_2_8_78_1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s13311-013-0253-y","article-title":"Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice","volume":"11","author":"Mancuso R.","year":"2014","journal-title":"Neurotherapeutics"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.22619"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2006.00192.x"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2011.12.001"},{"issue":"2","key":"e_1_2_8_82_1","first-page":"84","article-title":"Molecular targets of the natural antioxidant pterostilbene: effect on protein kinase C, caspase\u20103 and apoptosis in human neutrophils in vitro","volume":"31","author":"Perecko T.","year":"2010","journal-title":"Neuro Endocrinol Lett"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.12023"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1269\/jrr.10009"},{"key":"e_1_2_8_85_1","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1166\/jbn.2014.1897","article-title":"Resveratrol\u2010loaded nanoparticles reduce oxidative stress induced by radiation or amyloid\u2010beta in transgenic Caenorhabditis elegans","volume":"10","author":"Yin H.","year":"2014","journal-title":"J Biomed Nanotechnol"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2017.06.029"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1080\/13813455.2016.1182190"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2016.04.007"},{"key":"e_1_2_8_89_1","first-page":"525","article-title":"Resveratrol relieves ischemia\u2010induced oxidative stress in the hippocampus by activating SIRT1","volume":"10","author":"Meng Z.","year":"2015","journal-title":"Exp Ther Med"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-014-0441-1"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1021\/cn400094w"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2009.08.013"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2005.00318.x"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.060061"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq460"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/483501"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13431"},{"key":"e_1_2_8_98_1","doi-asserted-by":"crossref","first-page":"7862","DOI":"10.1523\/JNEUROSCI.0385-14.2014","article-title":"Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults","volume":"4","author":"Witte A. V.","year":"2014","journal-title":"J Neurosci"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28641"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114514000737"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.12360"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2011.08.015"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2011.05.026"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2015.11.003"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2013.05.018"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1159\/000477115"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(03)01441-9"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0000000000000417"},{"key":"e_1_2_8_109_1","first-page":"10420","article-title":"Resveratrol attenuates inflammation and oxidative stress induced by myocardial ischemia\u2010reperfusion injury: role of Nrf2\/ARE pathway","volume":"8","author":"Cheng L.","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2016.09.016"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1124\/mi.6.1.7"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2014.10.016"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-014-1220-8"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2012.11.009"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.4238\/2014.January.17.17"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-2011-1424"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2012.07.006"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0580364"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-011-0653-6"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2012.06.008"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-016-0504-2"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2016.11.018"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2014.2719"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2016.02.052"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408363.2013.805182"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2014.10.013"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.02.054"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/851267"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glr235"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2014.02.024"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.2337\/db12-0975"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2012.09.015"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12577"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2006.02.036"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.5b00378"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.13.19.2570"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1616"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890701408194"},{"key":"e_1_2_8_139_1","first-page":"2468","article-title":"The effects of calorie restriction on aging: a brief review","volume":"20","author":"Al\u2010Regaiey K. A.","year":"2016","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0180865"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.01.017"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2014.04.023"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/345105"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-016-1258-x"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2016.04.003"},{"key":"e_1_2_8_146_1","first-page":"227","article-title":"AMPK as a pro\u2010longevity target","volume":"107","author":"Burkewitz K.","year":"2016","journal-title":"EXS"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389450116666151102095825"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2015.1036060"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085495"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphs.2017.06.002"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12645"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2016.00241"},{"key":"e_1_2_8_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2016.02.022"},{"key":"e_1_2_8_154_1","first-page":"1","article-title":"Pterostilbene protects against UVB\u2010induced photo\u2010damage through a phosphatidylinositol\u20103\u2010kinase\u2010dependent Nrf2\/ARE pathway in human keratinocytes","volume":"22","author":"Li H.","year":"2017","journal-title":"Redox Rep"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2016.02.054"}],"container-title":["BioFactors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbiof.1400","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/biof.1400","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T09:26:30Z","timestamp":1719653190000},"score":1,"resource":{"primary":{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/10.1002\/biof.1400"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,6]]},"references-count":154,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/biof.1400"],"URL":"https:\/\/doi.org\/10.1002\/biof.1400","archive":["Portico"],"relation":{},"ISSN":["0951-6433","1872-8081"],"issn-type":[{"value":"0951-6433","type":"print"},{"value":"1872-8081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,6]]}}}