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Improved recognition of the mechanisms of ADs has led to the advancement of the management of these diseases. The principal mediators of ADs are inflammatory molecules. The herbal medicines due to their antioxidant and antiinflammatory properties have an important role in the management of ADs. Crocin is the principal chemical component extracted from saffron, which is a medicinal plant. This review focuses on the therapeutic effects of Crocin in various ADs.<\/jats:p>","DOI":"10.1002\/biof.1557","type":"journal-article","created":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T16:29:46Z","timestamp":1566318586000},"page":"835-843","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Therapeutic effects of Crocin in autoimmune diseases: A review"],"prefix":"10.1002","volume":"45","author":[{"given":"Shahla","family":"Korani","sequence":"first","affiliation":[{"name":"Research Center of Oils and Fats Kermanshah University of Medical Sciences  Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra","family":"Korani","sequence":"additional","affiliation":[{"name":"Nanotechnology Research Center, Buali (Avicenna) Research Center Mashhad University of Medical Science  Mashhad 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