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It has been documented to have a wide range of beneficial effects, including anti\u2010inflammatory, antioxidant, anti\u2010aging, anti\u2010allergic, antidiabetic, neuroprotective, cardioprotective, and chemopreventive properties. Piceatannol has significantly higher antioxidant activity than resveratrol. Piceatannol has been shown in preclinical studies to have the ability to inhibit or reduce the growth of cancers in various organs such as the brain, breast, lung, colon, cervical, liver, prostate, and skin. However, the bioavailability of\n                    <jats:italic>Piceatannol<\/jats:italic>\n                    is comparatively lower than\n                    <jats:italic>resveratrol<\/jats:italic>\n                    and other stilbenes. Several approaches have been reported in recent years to enhance its bioavailability and biological activity, and clinical trials are required to validate these findings. This review focuses on several aspects of natural stilbene\n                    <jats:italic>Piceatannol<\/jats:italic>\n                    , its chemistry, and its mechanism of action, and its promising therapeutic potential for the prevention and treatment of a wide variety of complex human diseases.\n                  <\/jats:p>","DOI":"10.1002\/biof.2009","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T06:35:39Z","timestamp":1694586939000},"page":"232-249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Exploring the therapeutic potential of naturally occurring piceatannol in non\u2010communicable diseases"],"prefix":"10.1002","volume":"50","author":[{"given":"Himanshu","family":"Gandhi","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences Shoolini University of Biotechnology and Management Sciences  Solan Himachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shikha","family":"Mahant","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Shoolini University of Biotechnology and Management Sciences  Solan Himachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Shoolini University of Biotechnology and Management Sciences  Solan Himachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Kumar","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Shoolini University of Biotechnology and Management Sciences  Solan Himachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Dua","sequence":"additional","affiliation":[{"name":"Discipline of Pharmacy Graduate School of Health, University of Technology Sydney  Ultimo New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5567-6663","authenticated-orcid":false,"given":"Dinesh Kumar","family":"Chellappan","sequence":"additional","affiliation":[{"name":"School of Pharmacy International Medical University  Bukit Jalil Kaula Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3823-6572","authenticated-orcid":false,"given":"Sachin Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Lovely Professional University  Phagwara Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7941-0229","authenticated-orcid":false,"given":"Gaurav","family":"Gupta","sequence":"additional","affiliation":[{"name":"School of Pharmacy Suresh Gyan Vihar University  Jaipur India"},{"name":"Center for Transdisciplinary Research Saveetha Institute of Medical and Technical Sciences, Saveetha University  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa A. 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