{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T14:33:05Z","timestamp":1779114785629,"version":"3.51.4"},"reference-count":56,"publisher":"Wiley","issue":"1-4","license":[{"start":{"date-parts":[[2008,12,19]],"date-time":"2008-12-19T00:00:00Z","timestamp":1229644800000},"content-version":"vor","delay-in-days":1448,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioFactors"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1002\/biof.5520250113","type":"journal-article","created":{"date-parts":[[2008,12,25]],"date-time":"2008-12-25T09:28:48Z","timestamp":1230197328000},"page":"117-126","source":"Crossref","is-referenced-by-count":51,"title":["Clinical trials of coenzyme Q<sub>10<\/sub> in neurological disorders"],"prefix":"10.1002","volume":"25","author":[{"given":"Clifford W.","family":"Shults","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Haas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,12,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1991.tb03962.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(98)00296-2"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10479"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410360613"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(00)01584-8"},{"key":"e_1_2_1_7_2","first-page":"215","volume-title":"Biomedical and Clinical Aspects of Coenzyme Q10","author":"Bogentoft C.","year":"1991"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(98)00006-9"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(90)90015-F"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410410514"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2005.01486.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000146894.45533.C2"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.3.515"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/415096a"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/35046114"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1523\/JNEUROSCI.22-05-01592.2002","article-title":"Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease","volume":"22","author":"Ferrante R.","year":"2002","journal-title":"Journal of Neurosciences"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/10715760290021216"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1096-7192(02)00145-2"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10024"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410390317"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.4.621"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.8.1170-b"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.4.621"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2003.10.002"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410410206"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.2.317"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000055089.39373.FC"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1001"},{"key":"e_1_2_1_29_2","first-page":"143","volume-title":"Biomedical and Clinical Aspects of Coenzyme","author":"Lucker P. W.","year":"1984"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(03)00185-X"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200105057"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.5.884"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(92)90237-P"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.7.849"},{"key":"e_1_2_1_35_2","doi-asserted-by":"publisher","DOI":"10.1080\/10715760290021207"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.7.2379"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.1.45"},{"key":"e_1_2_1_38_2","first-page":"288","article-title":"Human serum ubiquinol\u201010 levels and relationship to serum lipids","volume":"59","author":"Okamoto T.","year":"1989","journal-title":"International Journal of Vitamin Nutrition Research"},{"key":"e_1_2_1_39_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M302297200"},{"key":"e_1_2_1_40_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301213280305"},{"key":"e_1_2_1_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(02)00298-8"},{"key":"e_1_2_1_42_2","doi-asserted-by":"crossref","unstructured":"H.Reichmann A.Storch W. H.Jost P.Vieregge J.Spiegel W.Greulich J.Durner T.Mller A.Kupsch H.Henningsen W.Oertel G.FuchsandW.Kuhn Coenzym Q10\u2010Nanodispersion versus Plazebo zur symptomatischen Therapie von Patienten mit Morbus Parkinson. Eine multizentrische plazebokontrollierte randomisierte Doppelblindstudie 4. Deutscher Parkinson\u2010Kongress 2005.","DOI":"10.1055\/s-2005-866699"},{"key":"e_1_2_1_43_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.8.1275"},{"key":"e_1_2_1_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02531-9"},{"key":"e_1_2_1_45_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2002.00335.x"},{"key":"e_1_2_1_46_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.6.889"},{"key":"e_1_2_1_47_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000151975.03598.ED"},{"key":"e_1_2_1_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.10579"},{"key":"e_1_2_1_49_2","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1001\/archneur.59.10.1541","article-title":"Parkinson Study Group, Effects of coenzyme Q10 in early Parkinson disease\u2010Evidence of slowing of the functional decline","volume":"59","author":"Shults C. W.","year":"2002","journal-title":"Archives of Neurology"},{"key":"e_1_2_1_50_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.3.793"},{"key":"e_1_2_1_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2004.05.003"},{"key":"e_1_2_1_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2005.02.002"},{"key":"e_1_2_1_53_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.5.1238"},{"key":"e_1_2_1_54_2","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1212\/WNL.57.3.397","article-title":"A randomized, placebo\u2010controlled trial of coenzyme Q10 and remacemide in Huntington's disease","volume":"57","author":"The Huntington Study Group","year":"2001","journal-title":"Neurology"},{"key":"e_1_2_1_55_2","first-page":"536","article-title":"Pharmacokinetic study of deuterium\u2010labelled coenzyme Q10 in man","volume":"24","author":"Tomono Y.","year":"1986","journal-title":"International Journal of Clinical Pharmacology Therapeutics and Toxicology"},{"key":"e_1_2_1_56_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10371"},{"key":"e_1_2_1_57_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M004128200"}],"container-title":["BioFactors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbiof.5520250113","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/biof.5520250113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T06:38:42Z","timestamp":1693377522000},"score":1,"resource":{"primary":{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/10.1002\/biof.5520250113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":56,"journal-issue":{"issue":"1-4","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["10.1002\/biof.5520250113"],"URL":"https:\/\/doi.org\/10.1002\/biof.5520250113","archive":["Portico"],"relation":{},"ISSN":["0951-6433","1872-8081"],"issn-type":[{"value":"0951-6433","type":"print"},{"value":"1872-8081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}