{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T02:48:00Z","timestamp":1720752480367},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,12,19]],"date-time":"2008-12-19T00:00:00Z","timestamp":1229644800000},"content-version":"vor","delay-in-days":718,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioFactors"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Urinary catherization is a routine procedure in an intensive care unit (ICU) for monitoring the urine output of critically ill patients. The catheters which are most often used to help with urinary incontinence and retention also face problems like blockage, leakage and infection. These problems are due to proteins that adhere to the catheter surface and quickly build up on each other forming a protein layer. As the layers build up they can crystallize, providing the major source of blockage and leakage. Current strategies to avoid these problems include coating a catheter with silver alloy to reduce bacteria on the catheter surface. However, silver alloy coatings can lead to increased silver resistance for bacteria. Since silver is already used as an antibacterial agent in many places in a hospital, it is even more possible that resistance can develop. An alternative solution is presented involving coating latex, a common urinary catheter material with a micro layer (5\u2010100 microns) of polyethylene glycol. This hydrogel is applied using an interfacial photopolymerizatoin process with ethyl eosin as the photoinitiator. A 25 ppm concentration of ethyl eosin provided the strongest gel to surface adhesion and significantly lowered protein adhesion when compared to an uncoated latex substrate.<\/jats:p>","DOI":"10.1002\/biof.5520300403","type":"journal-article","created":{"date-parts":[[2008,12,25]],"date-time":"2008-12-25T09:53:00Z","timestamp":1230198780000},"page":"217-225","source":"Crossref","is-referenced-by-count":4,"title":["Application of poly ethylene glycol hydrogel to overcome latex urinary catheter related problems"],"prefix":"10.1002","volume":"30","author":[{"given":"Sriram","family":"Sankar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Rajalakshmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,12,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(98)00096-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00152192-200305000-00007"},{"key":"e_1_2_1_4_2","unstructured":"J.Gindes Medical Device Coatings Tech 25 Tech Journal South November 14 2004:http:\/\/www.techjournalsouth.com\/news\/article.html?.item id=747."},{"key":"e_1_2_1_5_2","first-page":"1","article-title":"Proteins at interfaces: current issues and future prospects in Protein at Interfaces, Physicochemical and Biochemical studies","volume":"602","author":"Horbett T.A.","year":"1995","journal-title":"ACS Symposium Series"},{"key":"e_1_2_1_6_2","unstructured":"W.Kao Biomedical Engineering 430: Biological Interactions with Materials Lecture presented at the University of Wisconsin\u2010Madison Madison WI 2006."},{"key":"e_1_2_1_7_2","volume-title":"Urinary Catheter, from the medical encyclopedia","author":"Knowles D.","year":"2005"},{"issue":"1","key":"e_1_2_1_8_2","first-page":"1","article-title":"Improving blood\u2010compatibility of polymeric surfaces [Electronic Version]","volume":"15","author":"Labarre D.","year":"2001","journal-title":"Trends in Biomaterials and Artificial Organs"},{"key":"e_1_2_1_9_2","first-page":"622","article-title":"Novel networks and gels containing increased amounts of grafted and crosslinked poly (ethylene glycol)","volume":"38","author":"Lowman A.M.","year":"1997","journal-title":"Polymer Preprints"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/978-1-4899-0703-5_14","volume-title":"Poly (Ethylene Oxide) and Blood Contact in Poly (Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications","author":"Merrill E.W.","year":"1992"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2004.05.002"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)61753-1"}],"container-title":["BioFactors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbiof.5520300403","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/biof.5520300403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T09:20:40Z","timestamp":1700040040000},"score":1,"resource":{"primary":{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/10.1002\/biof.5520300403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["10.1002\/biof.5520300403"],"URL":"https:\/\/doi.org\/10.1002\/biof.5520300403","archive":["Portico"],"relation":{},"ISSN":["0951-6433","1872-8081"],"issn-type":[{"value":"0951-6433","type":"print"},{"value":"1872-8081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}