{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:45:22Z","timestamp":1791402322966,"version":"4.3.3"},"reference-count":61,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,1,27]],"date-time":"2010-01-27T00:00:00Z","timestamp":1264550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biotechnology Journal"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this study, nanoporous gold supercapacitors were produced by electrochemical dealloying of gold\u2010silver alloy. Scanning electron microscopy and energy dispersive X\u2010ray spectroscopy confirmed completion of the dealloying process and generation of a porous gold material with \u223c10 nm diameter pores. Cyclic voltammetry and chronoamperometry of the nanoporous gold electrodes indicated that these materials exhibited supercapacitor behavior. The storage capacity of the electrodes measured by chronoamperometry was \u223c3 mC at 200 mV. Electrochemical storage and voltage\u2010controlled delivery of two model pharmacologic agents, benzylammonium and salicylic acid, was demonstrated. These results suggest that capacitance\u2010based storage and delivery of pharmacologic agents may serve as an alternative to conventional drug delivery methods.<\/jats:p>","DOI":"10.1002\/biot.200900250","type":"journal-article","created":{"date-parts":[[2010,1,27]],"date-time":"2010-01-27T12:12:05Z","timestamp":1264594325000},"page":"192-200","source":"Crossref","is-referenced-by-count":25,"title":["Supercapacitive transport of pharmacologic agents using nanoporous gold electrodes"],"prefix":"10.1002","volume":"5","author":[{"given":"Shaun D.","family":"Gittard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie E.","family":"Pierson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy M.","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung\u2010An Max","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger J.","family":"Narayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David B.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,2,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/10717540500455975"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-7402.2007.02115.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2006.01.004"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/193229680900300211"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e31816778f9"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2003.68.341"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1211\/jpp.61.06.0001"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.2741\/2794"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2008.00316.x"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/10717540500455975"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6446(04)03170-8"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1504"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","unstructured":"Elias P. M. The stratum corneum as an organ of protection old and new concepts in: Fritsch P. G. Hintner H. (Eds.) Current Problems in Dermatology S. Karger Ag Basel Switzerland 1989 pp. 10\u201321.","DOI":"10.1159\/000416833"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1304"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05921.x"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sna.2003.11.008"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2003.10.025"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016096626810"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700248"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2003.10.026"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(00)00138-1"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1586\/17434440.3.1.1"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2006.10.017"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-006-0028-9"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10544-005-3024-7"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.12.048"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700150"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4005(01)01028-0"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:BMMD.0000042047.83433.96"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2005.845240"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1089\/15209150050501961"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6223(00)00117-2"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199713151"},{"key":"e_1_2_1_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijhydene.2009.05.026"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.1832742"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.2051791"},{"key":"e_1_2_1_38_2","unstructured":"Pierson B. E. Characterization and Evaluation of a Novel Nanoporous Gold Biosensor Substrate M.S. thesis North Carolina State University 2009."},{"key":"e_1_2_1_39_2","doi-asserted-by":"publisher","DOI":"10.1006\/jcis.2002.8314"},{"key":"e_1_2_1_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4686(63)80042-0"},{"key":"e_1_2_1_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4686(64)85015-5"},{"key":"e_1_2_1_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4686(76)85147-X"},{"key":"e_1_2_1_43_2","doi-asserted-by":"publisher","DOI":"10.1149\/1.2425944"},{"key":"e_1_2_1_44_2","doi-asserted-by":"publisher","DOI":"10.1080\/01418618008239360"},{"key":"e_1_2_1_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbon.2004.12.028"},{"key":"e_1_2_1_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cplett.2005.01.032"},{"key":"e_1_2_1_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2297"},{"key":"e_1_2_1_48_2","doi-asserted-by":"publisher","DOI":"10.1149\/1.1836402"},{"key":"e_1_2_1_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.desal.2007.08.005"},{"key":"e_1_2_1_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-0728(93)80034-F"},{"key":"e_1_2_1_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-0728(88)80138-4"},{"key":"e_1_2_1_52_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma00173a027"},{"key":"e_1_2_1_53_2","doi-asserted-by":"publisher","DOI":"10.1039\/c39850000090"},{"key":"e_1_2_1_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(99)00531-0"},{"key":"e_1_2_1_55_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015940811827"},{"key":"e_1_2_1_56_2","doi-asserted-by":"publisher","DOI":"10.1177\/106002809603000703"},{"key":"e_1_2_1_57_2","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200405060-00009"},{"key":"e_1_2_1_58_2","first-page":"CD007403","article-title":"Topical rubefacients for acute and chronic pain in adults.","volume":"8","author":"Matthews P.","year":"2009","journal-title":"Cochrane Database Syst. Rev."},{"key":"e_1_2_1_59_2","unstructured":"Bard A. J. Faulkner L. R. (Eds.) Electrochemical Methods: Fundamentals and Applications John Wiley & Sons 1980 New York."},{"key":"e_1_2_1_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-0728(00)00423-X"},{"key":"e_1_2_1_61_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr60130a002"},{"key":"e_1_2_1_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-0728(68)80132-9"}],"container-title":["Biotechnology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbiot.200900250","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/biot.200900250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:38:37Z","timestamp":1759927117000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/biot.200900250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["10.1002\/biot.200900250"],"URL":"https:\/\/doi.org\/10.1002\/biot.200900250","archive":["Portico"],"relation":{},"ISSN":["1860-6768","1860-7314"],"issn-type":[{"value":"1860-6768","type":"print"},{"value":"1860-7314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}