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This study found that minor phenolic compounds in dry acid\u2010pretreated and biodetoxified wheat straw hydrolysates were the key inhibitors of\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    (\n                    <jats:italic>E. coli<\/jats:italic>\n                    ). Multiple\n                    <jats:italic>E. coli<\/jats:italic>\n                    strains exhibited poor cell growth and metabolic activity in wheat straw hydrolysates with the presence of minor phenolics. However, the cell growth and metabolic activity of\n                    <jats:italic>E. coli<\/jats:italic>\n                    strains were significantly recovered with the declining phenolic content. Several recombinant\n                    <jats:italic>E. coli<\/jats:italic>\n                    strains successfully fermented 22.17\u00a0g\/L of ethanol and synthesized 12.04\u00a0g\/L of cadaverine using wheat straw hydrolysates after the removal of minor phenolics. These findings highlight the critical role of phenolic compounds in the inhibition of\n                    <jats:italic>E. coli<\/jats:italic>\n                    strains and provide a foundation for\n                    <jats:italic>E. coli<\/jats:italic>\n                    recombinants in biorefinery fermentations for biofuel and biochemical productions.\n                  <\/jats:p>","DOI":"10.1002\/biot.70155","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T12:30:47Z","timestamp":1762777847000},"source":"Crossref","is-referenced-by-count":4,"title":["Minor Phenolic Compounds in Detoxified Lignocellulosic Hydrolysates Are the Determinant Factor on Cell Growth and Metabolic Activity of\n                    <i>Escherichia coli<\/i>"],"prefix":"10.1002","volume":"20","author":[{"given":"An","family":"Wang","sequence":"first","affiliation":[{"name":"School of Life Science Shanxi University  Taiyuan Shanxi 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