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The system that generated CL was made up of CoCl<jats:sub>2<\/jats:sub> and H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>. Incubation of psoralens in 0.2 m<jats:italic>M<\/jats:italic> doses with the generating system showed that only 8\u2010methoxypsoralen and khellin have antioxidative effects. Antioxidative effects were also observed in the case of visnagin but in low concentration (0.05 m<jats:italic>M<\/jats:italic>). High doses of psoralens (1 m<jats:italic>M<\/jats:italic>) showed prooxidative effects. Measurements were done using a deoxyribose assay, the CL method, and spin\u2010trapping with 5,5\u2010dimethyl\u20101\u2010pyrroline\u2010<jats:italic>N<\/jats:italic>\u2010oxide and 2,2,6,6\u2010tetramethylpiperidine combined with electron spin resonance spectroscopy and spectrophotometry methods. \u00a9 2002 Wiley Periodicals, Inc. 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