{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T13:40:45Z","timestamp":1698068445286},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"vor","delay-in-days":5419,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biopolymers"],"published-print":{"date-parts":[[1989,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report dynamic light scattering measurements over a wide range of scattering vectors for fractionated samples of porcine submaxillary mucin (PSM) glycoproteins in two different solvents: 0.1<jats:italic>M<\/jats:italic> NaCl, and 6<jats:italic>M<\/jats:italic> GdnHCl. The relaxation spectrum has been successfully resolved into a slow mode corresponding to pure translational diffusion and a fast mode containing information on the relaxation times for intramolecular motion. Analysis of the slow mode permits a light scattering evaluation of the polydispersity of these high molecular weight mucin glycoprotein fractions. Determination of the longest intramolecular relaxation times \u03c4<jats:sub>1<\/jats:sub> shows that these are much longer for the PSM fractions in 0.1<jats:italic>M<\/jats:italic> NaCl compared to 6<jats:italic>M<\/jats:italic> GdnHCl. These data are consistent with earlier studies showing that the chain conformation is the same in both solvents, but that in 0.1<jats:italic>M<\/jats:italic> NaCl, the PSM glycoprotein undergoes a self\u2010association process that is end\u2010to\u2010end in nature. Since the \u03c4<jats:sub>1<\/jats:sub> value is intimately related to the viscoelastic behavior of PSM solutions and gels, it is interesting to speculate that the end\u2010to\u2010end association process may be physiologically important.<\/jats:p>","DOI":"10.1002\/bip.360280402","type":"journal-article","created":{"date-parts":[[2004,12,30]],"date-time":"2004-12-30T01:14:08Z","timestamp":1104369248000},"page":"785-797","source":"Crossref","is-referenced-by-count":2,"title":["Dynamic light scattering studies of porcine submaxillary mucin fractions in dilute solution at intermediate scattering vectors"],"prefix":"10.1002","volume":"28","author":[{"given":"B. K.","family":"Varma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Demers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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