{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T03:10:10Z","timestamp":1786245010875,"version":"build-2736575974"},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T00:00:00Z","timestamp":1744329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003093","name":"Ministry of Higher Education, Malaysia","doi-asserted-by":"publisher","award":["FRGS\/1\/2019\/TK05\/UTM\/02\/15"],"award-info":[{"award-number":["FRGS\/1\/2019\/TK05\/UTM\/02\/15"]}],"id":[{"id":"10.13039\/501100003093","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003093","name":"Ministry of Higher Education, Malaysia","doi-asserted-by":"publisher","award":["Potential Academic Staff (Q.J130000.2746.03K93)"],"award-info":[{"award-number":["Potential Academic Staff (Q.J130000.2746.03K93)"]}],"id":[{"id":"10.13039\/501100003093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biopolymers"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Silk fibroin (SF), a biodegradable and biocompatible material with excellent mechanical properties, is widely utilized in food packaging and medical applications. However, regenerated SF is inherently brittle, necessitating the addition of polyethylene glycol (PEG), a nontoxic and biocompatible plasticizer, to enhance its flexibility. In this study, SF\u2010PEG films were fabricated using two solvent systems: a single solvent (1\u2010butyl\u20103\u2010methylimidazolium chloride, BMIM Cl) and a binary solvent system (BMIM Cl and dimethyl sulfoxide, DMSO). SL\u2010PEG films were prepared using the single solvent, while SM\u2010PEG films were produced with the binary solvent system. The structural, mechanical, and morphological properties of the films were compared. Results showed that the SM\u2010PEG films exhibited excellent mechanical performance, with a tensile strength of 6.9\u2009\u00b1\u20090.7\u2009MPa, a Young's modulus of 367.0\u2009\u00b1\u200942.9\u2009MPa, and an elongation at break of 42.6%\u2009\u00b1\u20094.0%, significantly outperforming the SL\u2010PEG films. The enhanced performance of SM\u2010PEG films was attributed to the improved dispersion of PEG within the SF matrix, facilitated by the binary solvent system. In conclusion, the binary solvent system effectively improved the flexibility and ductility of SF\u2010PEG films, making them better suited for applications requiring robust and adaptable biomaterials, such as in food packaging and medical applications.<\/jats:p>","DOI":"10.1002\/bip.70015","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T13:18:36Z","timestamp":1744377516000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ionic Liquid and Binary Solvent Assisted Preparation of\u00a0Silk Fibroin and Polyethylene Glycol Film: Structural and\u00a0Mechanical Properties"],"prefix":"10.1002","volume":"116","author":[{"given":"Jia Tee","family":"Low","sequence":"first","affiliation":[{"name":"Faculty of Chemical and Energy Engineering Universiti Teknologi Malaysia  Johor Bahru Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5805-4421","authenticated-orcid":false,"given":"Noor Izyan Syazana Mohd","family":"Yusoff","sequence":"additional","affiliation":[{"name":"Faculty of Chemical and Energy Engineering Universiti Teknologi Malaysia  Johor Bahru Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mat Uzir","family":"Wahit","sequence":"additional","affiliation":[{"name":"Faculty of Chemical and Energy Engineering Universiti Teknologi Malaysia  Johor Bahru Malaysia"},{"name":"Centre for Advanced Composite Materials (CACM), Universiti Teknologi Malaysia  Johor Bahru Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norhayani","family":"Othman","sequence":"additional","affiliation":[{"name":"Faculty of Chemical and Energy Engineering Universiti Teknologi Malaysia  Johor Bahru Malaysia"},{"name":"Centre for Advanced Composite Materials (CACM), Universiti Teknologi Malaysia  Johor Bahru Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bip.23554"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.130374"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.124407"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bip.22993"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2012.06.007"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2014.06.022"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2011.379"},{"key":"e_1_2_8_9_1","first-page":"91","article-title":"Dissolution of Silk Fibroin with CalciumChloride\/Ethanol Aqueous Solution Studies on the Dissolution of Silk Fibroin. 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