{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:50:56Z","timestamp":1759971056050,"version":"build-2065373602"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,6,16]],"date-time":"2014-06-16T00:00:00Z","timestamp":1402876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Dutch Ministry of Economic Affairs"},{"name":"European Union Regional Development Fund"},{"name":"Province of Friesland the City of Leeuwarden"},{"name":"EZ\/Kompas program of the \u201cSamenwerkingsverband Noord-Nederland\u201d"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biotech &amp; Bioengineering"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label\/><jats:p>Granular activated carbon (GAC) is used in water treatment systems, typically to remove pollutants such as natural organic matter, volatile organic compounds, chlorine, taste, and odor. GAC is also used as a key component of a new technology that combines a fluidized bed reactor with radio frequency electric fields for disinfection. So far, the effects of GAC on bacteria in these fluidized bed reactors are unclear. This paper describes a systematic study of the physico\u2010chemical changes in five microbial media compositions caused by different concentrations (23\u2013350\u2009g\/L) of GAC, and the effects of these physico\u2010chemical changes on the metabolic activity and survival of a model microorganism (<jats:italic>Escherichia coli<\/jats:italic> YMc10) in a fluidized bed reactor. The chemical adsorption taking place in suspensions with specific GAC changed nutritional, osmotic, and pH conditions in the investigated microbial media (LB, diluted LB, PBS, diluted PBS, and tap water), leading to a decay of the metabolic activity and survival of <jats:italic>E. coli<\/jats:italic>. Especially media that are poor in organic and mineral compounds (e.g., PBS) with suspended GAC showed a concentration decay of 3.5\u2009Log CFU\/mL <jats:italic>E. coli<\/jats:italic> after 6\u2009h. Organic compounds depletion and severe pH variation were enhanced in the presence of higher GAC concentrations. Biotechnol. Bioeng. 2014;111: 2009\u20132018. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bit.25254","type":"journal-article","created":{"date-parts":[[2014,4,12]],"date-time":"2014-04-12T01:38:35Z","timestamp":1397266715000},"page":"2009-2018","source":"Crossref","is-referenced-by-count":1,"title":["Effect of granular activated carbon concentration on the content of organic matter and salt, influencing <i>E. coli<\/i> activity and survival in fluidized bed disinfection reactor"],"prefix":"10.1002","volume":"111","author":[{"given":"Justina","family":"Racyte","sequence":"first","affiliation":[{"name":"Wetsus Centre of Excellence for Sustainable Water Technology P.O. Box 1113 8900 CC Leeuwarden The Netherlands"},{"name":"Wageningen University Sub\u2010Department of Environmental Technology P.O. Box 17 6700 AA Wageningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alette A.M.","family":"Langenhoff","sequence":"additional","affiliation":[{"name":"Wageningen University Sub\u2010Department of Environmental Technology P.O. Box 17 6700 AA Wageningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana F.M.M.R.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Wetsus Centre of Excellence for Sustainable Water Technology P.O. Box 1113 8900 CC Leeuwarden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid H.","family":"Paulitsch\u2010Fuchs","sequence":"additional","affiliation":[{"name":"Wetsus Centre of Excellence for Sustainable Water Technology P.O. Box 1113 8900 CC Leeuwarden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Bruning","sequence":"additional","affiliation":[{"name":"Wageningen University Sub\u2010Department of Environmental Technology P.O. Box 17 6700 AA Wageningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huub H.M.","family":"Rijnaarts","sequence":"additional","affiliation":[{"name":"Wageningen University Sub\u2010Department of Environmental Technology P.O. Box 17 6700 AA Wageningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6941.2009.00745.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01981-05"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2010.07.023"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90063-6"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/08827500802045586"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2009.10.011"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2166\/wst.1999.0593"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002217240001158X"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.03.100149.002103"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6223(03)00123-4"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.58.030603.123818"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2005.09.010"},{"key":"e_1_2_5_14_1","first-page":"252","volume-title":"Drinking water disinfection techniques","author":"Pandit AB","year":"2012"},{"key":"e_1_2_5_15_1","first-page":"1026","volume-title":"Microbiology","author":"Prescott LM","year":"2002"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2013.08.011"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbon.2011.07.054"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02213-06"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.69.6.3359-3367.2003"},{"key":"e_1_2_5_20_1","first-page":"655","volume-title":"General microbiology","author":"Schlegel HG","year":"1993"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01368-07"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0045-6535(95)00087-O"},{"key":"e_1_2_5_23_1","first-page":"868","volume-title":"Elementary statistics: with multimedia study guide","author":"Triola MF","year":"2007"},{"key":"e_1_2_5_24_1","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1128\/AEM.65.2.813-821.1999","article-title":"Simultaneous monitoring of cell number and metabolic activity of specific bacterial populations with a Dualgfp\u2010luxAB marker system","volume":"65","author":"Unge A","year":"1999","journal-title":"Appl Environ Microb"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/bit.21820"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2008.01664.x"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/es60143a005"},{"key":"e_1_2_5_28_1","unstructured":"WHO 2011. Guidelines for drinking\u2010water quality. Accessed 20.5.2013.http:\/\/www.who.int\/water_sanitation_health\/publications\/2011\/dwq_chapters\/en\/."},{"key":"e_1_2_5_29_1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1128\/aem.40.2.386-390.1980","article-title":"Cell envelope damage in Escherichia coli caused by short\u2010term stress in water","volume":"40","author":"Zaske SK","year":"1980","journal-title":"Appl Environ Microb"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.158.1.246-252.1984"}],"container-title":["Biotechnology and Bioengineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbit.25254","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bit.25254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:09:48Z","timestamp":1759925388000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bit.25254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,16]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1002\/bit.25254"],"URL":"https:\/\/doi.org\/10.1002\/bit.25254","archive":["Portico"],"relation":{},"ISSN":["0006-3592","1097-0290"],"issn-type":[{"type":"print","value":"0006-3592"},{"type":"electronic","value":"1097-0290"}],"subject":[],"published":{"date-parts":[[2014,6,16]]}}}