{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:02:50Z","timestamp":1784887370297,"version":"3.55.0"},"reference-count":44,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biotech &amp; Bioengineering"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Alopecia is a common dermatologic disorder with psychological and quality\u2010of\u2010life impact. Current options such as PRP, topical agents, microneedling or dermarollers, drugs, and transplantation, often provide only partial or short\u2010term benefit and depend on existing follicles. 3D bioprinting is transforming regenerative trichology by positioning cells and \u201cbioinks\u201d to recreate hair\u2010bearing skin. Advances include biomimetic dermal papilla spheroids, follicle organoids in engineered dermis, and bioprinted skin equivalents with nascent HF\u2010like structures. Translation is limited by vascular and nerve integration and hair\u2010cycle control. These priorities will enable robust clinical regeneration. This review recapitulates the recent advances at the interface of hair\u2010follicle biology and 3D bioprinting, and delineates key bioengineering and cellular components underpinning folliculogenesis. Recent advancements have enabled the fabrication of biomimetic dermal papilla spheroids, the spatial integration of hair\u2010follicle organoids within engineered dermal matrices, and the fabrication of bioprinted skin equivalents containing nascent HF\u2010like structures, representing functional relevance for pharmacological evaluation and regenerative transplantation studies. Clinical translation of hair bioprinting remains impeded by the integration of functional vascular and neural networks, and recapitulating hair\u2010cycle dynamics. This review outlines strategic priorities required to move the field from experimental proof of concept to scalable, clinically relevant hair regeneration using bio\u2010prinking technology.<\/jats:p>","DOI":"10.1002\/bit.70250","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T07:11:42Z","timestamp":1779347502000},"page":"2153-2161","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["\u201cBioprinting of Hair: How Far We Proceeded and What Needs to be Done\u201d"],"prefix":"10.1002","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3797-7133","authenticated-orcid":false,"given":"Mamata","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Research The Esthetic Clinics Clinical Research Organization (TECCRO) Mumbai Maharashtra 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