{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:16:21Z","timestamp":1790414181511,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The treatment of end-stage lymphoedema of the leg is challenging, especially when conservative treatment fails and there is a large volume difference between the affected and unaffected legs. Circumferential suction-assisted lipectomy (CSAL) has been described as a treatment option for end-stage lymphoedema of the leg. Here, the long-term results of CSAL in end-stage primary and secondary lymphoedema of the leg were analysed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a descriptive study of patients treated with CSAL for unilateral chronic irreversible lymphoedema of the leg. Compression therapy was resumed after surgery. Leg volumes were measured before surgery, and at 1, 6, 12 and 24 months after the procedure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 47 patients with primary lymphoedema had a median preoperative volume difference between affected and unaffected legs of 3686 (i.q.r. 2851\u20135121) ml. Two years after surgery, this volume difference was reduced to 761 ml, a 79 per cent reduction. In the 41 patients treated for secondary lymphoedema, the median preoperative volume difference was 3320 (i.q.r. 2533\u20134783) ml, decreasing after 2 years to \u221238 ml (101 per cent reduction). The preoperative volume difference and the sex of the patient significantly influenced the final outcome after 2 years. The outcome was not related to BMI or other patient characteristics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>CSAL is an effective method for treating both primary and secondary lymphoedema of the leg.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.10325","type":"journal-article","created":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T13:49:35Z","timestamp":1478180975000},"page":"84-89","source":"Crossref","is-referenced-by-count":37,"title":["Circumferential suction-assisted lipectomy in the treatment of primary and secondary end-stage lymphoedema of the leg"],"prefix":"10.1093","volume":"104","author":[{"given":"D-A A","family":"Lamprou","sequence":"first","affiliation":[{"name":"Expert Centre of Lympho-Vascular Medicine, Departments of Vascular Surgery, Nij Smellinghe Hospital , Drachten,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H G J","family":"Voesten","sequence":"additional","affiliation":[{"name":"Expert Centre of Lympho-Vascular Medicine, Departments of Vascular Surgery, Nij Smellinghe Hospital , Drachten,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R J","family":"Damstra","sequence":"additional","affiliation":[{"name":"Departments of Dermatology, Nij Smellinghe Hospital , Drachten,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O R M","family":"Wikkeling","sequence":"additional","affiliation":[{"name":"Expert Centre of Lympho-Vascular Medicine, Departments of Vascular Surgery, Nij Smellinghe Hospital , Drachten,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,1,1]]},"reference":[{"key":"2024092914161926000_bjs10325-bib-0001","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1245\/ASO.2004.04.017","article-title":"Lymphoedema secondary to postmastectomy radiation: incidence and risk factors","volume":"11","author":"Hinrichs","year":"2004","journal-title":"Ann Surg Oncol"},{"key":"2024092914161926000_bjs10325-bib-0002","first-page":"156","article-title":"Developmental disorders of the lymphatic system","volume":"26","author":"Greenlee","year":"1993","journal-title":"Lymphology"},{"key":"2024092914161926000_bjs10325-bib-0003","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1089\/lrb.2006.4404","article-title":"Adipose tissue dominates chronic arm lymphoedema following breast cancer: an analysis using volume rendered CT images","volume":"4","author":"Brorson","year":"2006","journal-title":"Lymphat Res 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