{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:40:08Z","timestamp":1791819608618,"version":"4.3.4"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T00:00:00Z","timestamp":1612569600000},"content-version":"vor","delay-in-days":1291,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"UK NIHR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000664","name":"UK NIHR HTA","doi-asserted-by":"publisher","award":["14\/179\/01"],"award-info":[{"award-number":["14\/179\/01"]}],"id":[{"id":"10.13039\/501100000664","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Applied Research programme","award":["RP-PG-1210-12009"],"award-info":[{"award-number":["RP-PG-1210-12009"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The UK abdominal aortic aneurysm (AAA) screening programmes currently invite only men for screening because the benefit in women is uncertain. Perioperative risk is critical in determining the effectiveness of screening, and contemporary estimates of these risks in women are lacking. The aim of this study was to compare mortality following AAA repair between women and men in the UK.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Anonymized data from the UK National Vascular Registry (NVR) for patients undergoing AAA repair (January 2010 to December 2014) were analysed. Co-variables were extracted for analysis by sex. The primary outcome measure was in-hospital mortality. Secondary outcome measures included mortality by 5-year age groups and duration of hospital stay. Logistic regression was performed to adjust for age, calendar time, AAA diameter and smoking status. NVR-based outcomes were checked against Hospital Episode Statistics (HES) data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 23 245 patients were included (13\u00b70 per cent women). Proportionally, more women than men underwent open repair. For elective open AAA repair, the in-hospital mortality rate was 6\u00b79 per cent in women and 4\u00b70 per cent in men (odds ratio (OR) 1\u00b748, 95 per cent c.i. 1\u00b708 to 2\u00b702; P = 0\u00b7014), whereas for elective endovascular AAA repair it was 1\u00b78 per cent in women and 0\u00b77 per cent in men (OR 2\u00b786, 1\u00b772 to 4\u00b774; P &amp;lt; 0\u00b7001); the results in HES were similar. For ruptured AAA, there was no sex difference in mortality within the NVR; however, in HES, for ruptured open AAA repair, the in-hospital mortality rate was higher in women (33\u00b76 versus 27\u00b71 per cent; OR 1\u00b736, 1\u00b716 to 1\u00b759; P &amp;lt; 0\u00b7001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Women have a higher in-hospital mortality rate than men after elective AAA repair even after adjustment. This higher mortality may have an impact on the benefit offered by any screening programme offered to women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bjs.10600","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T07:22:43Z","timestamp":1501053763000},"page":"1656-1664","source":"Crossref","is-referenced-by-count":68,"title":["Sex differences in mortality after abdominal aortic aneurysm repair in the UK"],"prefix":"10.1093","volume":"104","author":[{"given":"D A","family":"Sidloff","sequence":"first","affiliation":[{"name":"Vascular Surgery Group, Department of Cardiovascular Sciences and National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, University of Leicester, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Saratzis","sequence":"additional","affiliation":[{"name":"Vascular Surgery Group, Department of Cardiovascular Sciences and National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, University of Leicester, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M J","family":"Sweeting","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Michaels","sequence":"additional","affiliation":[{"name":"Health Economics and Decision Science, University of Sheffield, Sheffield, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J T","family":"Powell","sequence":"additional","affiliation":[{"name":"Vascular Surgery Research Group, Imperial College, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S G","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M J","family":"Bown","sequence":"additional","affiliation":[{"name":"Vascular Surgery Group, Department of Cardiovascular Sciences and National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, University of Leicester, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,7,26]]},"reference":[{"key":"2021020617165117900_bjs10600-bib-0001","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1002\/bjs.8897","article-title":"Final follow-up of the multicentre aneurysm screening study (MASS) randomized trial of abdominal aortic aneurysm screening","volume":"99","author":"Thompson","year":"2012","journal-title":"Br J Surg"},{"key":"2021020617165117900_bjs10600-bib-0002","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1002\/bjs.9528","article-title":"Cost-effectiveness of the National Health Service 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