{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:02:21Z","timestamp":1791540141295,"version":"4.3.4"},"reference-count":133,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Gallbladder cancer is rare, but cancers detected incidentally after cholecystectomy are increasing. The aim of this study was to review the available data for current best practice for optimal management of incidental gallbladder cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A systematic PubMed search of the English literature to May 2018 was conducted.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The search identified 12 systematic reviews and meta-analyses, in addition to several consensus reports, multi-institutional series and national audits. Some 0\u00b725\u20130\u00b789 per cent of all cholecystectomy specimens had incidental gallbladder cancer on pathological examination. Most patients were staged with pT2 (about half) or pT1 (about one-third) cancers. Patients with cancers confined to the mucosa (T1a or less) had 5-year survival rates of up to 100 per cent after cholecystectomy alone. For cancers invading the muscle layer of the gallbladder wall (T1b or above), reresection is recommended. The type, extent and timing of reresection remain controversial. Observation time may be used for new cross-sectional imaging with CT and MRI. Perforation at initial surgery had a higher risk of disease dissemination. Gallbladder cancers are PET-avid, and PET may detect residual disease and thus prevent unnecessary surgery. Routine laparoscopic staging before reresection is not warranted for all stages. Risk of peritoneal carcinomatosis increases with each T category. The incidence of port-site metastases is about 10 per cent. Routine resection of port sites has no effect on survival. Adjuvant chemotherapy is poorly documented and probably underused.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Management of incidental gallbladder cancer continues to evolve, with more refined suggestions for subgroups at risk and a selective approach to reresection.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.11035","type":"journal-article","created":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T10:17:38Z","timestamp":1545646658000},"page":"32-45","source":"Crossref","is-referenced-by-count":130,"title":["Systematic review of management of incidental gallbladder cancer after cholecystectomy"],"prefix":"10.1093","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7594-4354","authenticated-orcid":false,"given":"K","family":"S\u00f8reide","sequence":"first","affiliation":[{"name":"Clinical Surgery, Royal Infirmary of Edinburgh and University of Edinburgh , Edinburgh,","place":["UK"]},{"name":"Department of Gastrointestinal Surgery, Stavanger University Hospital , Stavanger,","place":["Norway"]},{"name":"Department of Clinical Medicine, University of Bergen , Bergen,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R V","family":"Guest","sequence":"additional","affiliation":[{"name":"Clinical Surgery, Royal Infirmary of Edinburgh and University of Edinburgh , Edinburgh,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E M","family":"Harrison","sequence":"additional","affiliation":[{"name":"Clinical Surgery, Royal Infirmary of Edinburgh and University of Edinburgh , Edinburgh,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4174-2786","authenticated-orcid":false,"given":"T J","family":"Kendall","sequence":"additional","affiliation":[{"name":"Division of Pathology, Royal Infirmary of Edinburgh and University of Edinburgh , Edinburgh,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O J","family":"Garden","sequence":"additional","affiliation":[{"name":"Clinical Surgery, Royal Infirmary of Edinburgh and University of Edinburgh , Edinburgh,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S J","family":"Wigmore","sequence":"additional","affiliation":[{"name":"Clinical Surgery, Royal Infirmary of Edinburgh and University of Edinburgh , Edinburgh,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,1,1]]},"reference":[{"key":"2024092914180177200_bjs11035-bib-0001","doi-asserted-by":"crossref","first-page":"1532835","DOI":"10.1155\/2017\/1532835","article-title":"Gallbladder carcinoma in the United States: a population based clinical outcomes study involving 22 343 patients from the surveillance, epidemiology, and end result database (1973\u20132013)","volume":"2017","author":"Lau","year":"2017","journal-title":"HPB Surg"},{"key":"2024092914180177200_bjs11035-bib-0002","first-page":"159","article-title":"A 10-year experience in the management of gallbladder cancer","volume":"5","author":"Smith","year":"2003","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0003","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s12029-017-0036-5","article-title":"Staging, treatment, and future approaches of gallbladder carcinoma","volume":"49","author":"Shukla","year":"2018","journal-title":"J Gastrointest Cancer"},{"key":"2024092914180177200_bjs11035-bib-0004","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1177\/1457496916630645","article-title":"Use of laparoscopy in gastrointestinal surgery in Sweden 1998\u20132014: a nationwide study","volume":"106","author":"Sundbom","year":"2017","journal-title":"Scand J Surg"},{"key":"2024092914180177200_bjs11035-bib-0005","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1177\/000313481408000718","article-title":"Changing demographics in laparoscopic cholecystectomy performed in the United States: hospitalizations from 1998 to 2010","volume":"80","author":"Tucker","year":"2014","journal-title":"Am Surg"},{"key":"2024092914180177200_bjs11035-bib-0006","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1007\/s00268-017-4215-0","article-title":"Are incidental gallbladder cancers missed with a selective approach of gallbladder histology at cholecystectomy?","volume":"42","author":"Lundgren","year":"2018","journal-title":"World J Surg"},{"key":"2024092914180177200_bjs11035-bib-0007","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1007\/s00464-016-5002-y","article-title":"Histopathological examination of specimen following cholecystectomy: are we accepting resect and discard?","volume":"31","author":"Wrenn","year":"2017","journal-title":"Surg Endosc"},{"key":"2024092914180177200_bjs11035-bib-0008","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.hpb.2017.11.006","article-title":"The risk of incidental gallbladder cancer is negligible in macroscopically normal cholecystectomy specimens","volume":"20","author":"Koppatz","year":"2018","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0009","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1477-2574.2012.00443.x","article-title":"All cholecystectomy specimens must be sent for histopathology to detect inapparent gallbladder cancer","volume":"14","author":"Agarwal","year":"2012","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0010","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.3748\/wjg.v21.i4.1315","article-title":"Clinical characteristics of incidental or unsuspected gallbladder cancers diagnosed during or after cholecystectomy: a systematic review and meta-analysis","volume":"21","author":"Choi","year":"2015","journal-title":"World J Gastroenterol"},{"key":"2024092914180177200_bjs11035-bib-0011","doi-asserted-by":"crossref","first-page":"4913","DOI":"10.2147\/OTT.S106580","article-title":"Incidental gallbladder cancer after cholecystectomy: 1990 to 2014","volume":"9","author":"Dorobisz","year":"2016","journal-title":"Onco Targets Ther"},{"key":"2024092914180177200_bjs11035-bib-0012","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1308\/rcsann.2015.0013","article-title":"Routine versus selective histological examination after cholecystectomy to exclude incidental gallbladder carcinoma","volume":"97","author":"Emmett","year":"2015","journal-title":"Ann R Coll Surg Engl"},{"key":"2024092914180177200_bjs11035-bib-0013","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/jso.24546","article-title":"Global epidemiological trends and variations in the burden of gallbladder cancer","volume":"115","author":"Are","year":"2017","journal-title":"J Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0014","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jamcollsurg.2010.09.009","article-title":"Gallbladder cancer: differences in presentation, surgical treatment, and survival in patients treated at centers in three countries","volume":"212","author":"Butte","year":"2011","journal-title":"J Am Coll Surg"},{"key":"2024092914180177200_bjs11035-bib-0015","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1177\/000313481708300721","article-title":"Pathologic and prognostic implications of incidental versus nonincidental gallbladder cancer: a 10-institution study from the United States extrahepatic biliary malignancy consortium","volume":"83","author":"Ethun","year":"2017","journal-title":"Am Surg"},{"key":"2024092914180177200_bjs11035-bib-0016","doi-asserted-by":"crossref","first-page":"185","DOI":"10.4103\/jmas.JMAS_223_16","article-title":"Laparoscopic versus open treatment of gallbladder cancer: a systematic review and meta-analysis","volume":"14","author":"Zhao","year":"2018","journal-title":"J Minim Access Surg"},{"key":"2024092914180177200_bjs11035-bib-0017","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.surg.2016.08.007","article-title":"Trends in port-site metastasis after laparoscopic resection of incidental gallbladder cancer: a systematic review","volume":"161","author":"Berger-Richardson","year":"2017","journal-title":"Surgery"},{"key":"2024092914180177200_bjs11035-bib-0018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.hpb.2015.07.008","article-title":"A systematic review of safety and efficacy of hepatopancreatoduodenectomy for biliary and gallbladder cancers","volume":"18","author":"Zhou","year":"2016","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0019","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.surge.2016.06.004","article-title":"Routine extra-hepatic bile duct resection in gallbladder cancer patients without bile duct infiltration: a systematic review","volume":"14","author":"Nigri","year":"2016","journal-title":"Surgeon"},{"key":"2024092914180177200_bjs11035-bib-0020","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/apt.12900","article-title":"Systematic review with network meta-analysis: adjuvant therapy for resected biliary tract cancer","volume":"40","author":"Zhu","year":"2014","journal-title":"Aliment Pharmacol Ther"},{"key":"2024092914180177200_bjs11035-bib-0021","doi-asserted-by":"crossref","first-page":"174","DOI":"10.3748\/wjg.v17.i2.174","article-title":"Systematic review on the surgical treatment for T1 gallbladder cancer","volume":"17","author":"Lee","year":"2011","journal-title":"World J Gastroenterol"},{"key":"2024092914180177200_bjs11035-bib-0022","doi-asserted-by":"crossref","first-page":"11481","DOI":"10.3748\/wjg.v21.i40.11481","article-title":"Diagnostic accuracy of fluorine-18-fluorodeoxyglucose positron emission tomography in gallbladder cancer: a meta-analysis","volume":"21","author":"Annunziata","year":"2015","journal-title":"World J Gastroenterol"},{"key":"2024092914180177200_bjs11035-bib-0023","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.ijsu.2014.07.010","article-title":"Routine histological analysis of a macroscopically normal gallbladder \u2013 a review of the literature","volume":"12","author":"Jamal","year":"2014","journal-title":"Int J Surg"},{"key":"2024092914180177200_bjs11035-bib-0024","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ctrv.2011.05.003","article-title":"Is adjuvant radiotherapy needed after curative resection of extrahepatic biliary tract cancers? A systematic review with a meta-analysis of observational studies","volume":"38","author":"Bonet Beltr\u00e1n","year":"2012","journal-title":"Cancer Treat Rev"},{"key":"2024092914180177200_bjs11035-bib-0025","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.hpb.2017.05.010","article-title":"Adjuvant chemotherapy for resected biliary tract cancers: a systematic review and meta-analysis","volume":"19","author":"Ghidini","year":"2017","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0026","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1200\/JCO.2011.40.5381","article-title":"Adjuvant therapy in the treatment of biliary tract cancer: a systematic review and meta-analysis","volume":"30","author":"Horgan","year":"2012","journal-title":"J Clin Oncol"},{"key":"2024092914180177200_bjs11035-bib-0027","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1111\/hpb.12432","article-title":"Consensus conference on gallbladder cancer","volume":"17","author":"Shroff","year":"2015","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0028","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/hpb.12444","article-title":"Gallbladder cancer: expert consensus statement","volume":"17","author":"Aloia","year":"2015","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0029","article-title":"Laparoscopic surgery for gallbladder cancer: an expert consensus statement","author":"Han","year":"2018","journal-title":"Dig Surg"},{"key":"2024092914180177200_bjs11035-bib-0030","doi-asserted-by":"crossref","first-page":"79","DOI":"10.4103\/0971-5851.158829","article-title":"Indian Council of Medical Research consensus document for the management of gall bladder cancer","volume":"36","author":"Shukla","year":"2015","journal-title":"Indian J Med Paediatr Oncol"},{"key":"2024092914180177200_bjs11035-bib-0031","doi-asserted-by":"crossref","first-page":"v28","DOI":"10.1093\/annonc\/mdw324","article-title":"ESMO Guidelines Committee. Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"27","author":"Valle","year":"2016","journal-title":"Ann Oncol"},{"key":"2024092914180177200_bjs11035-bib-0032","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.3346\/jkms.2014.29.10.1333","article-title":"Korean Association of Hepato-Biliary and Pancreas Surgery. Practical guidelines for the surgical treatment of gallbladder cancer","volume":"29","author":"Lee","year":"2014","journal-title":"J Korean Med Sci"},{"key":"2024092914180177200_bjs11035-bib-0033","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.6004\/jnccn.2014.0112","article-title":"Hepatobiliary cancers, version 2.2014","volume":"12","author":"Benson","year":"2014","journal-title":"J Natl Compr Canc Netw"},{"key":"2024092914180177200_bjs11035-bib-0034","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1002\/jso.24591","article-title":"Routine port-site excision in incidentally discovered gallbladder cancer is not associated with improved survival: a multi-institution analysis from the US Extrahepatic Biliary Malignancy Consortium","volume":"115","author":"Ethun","year":"2017","journal-title":"J Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0035","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1001\/jamasurg.2016.3642","article-title":"Association of optimal time interval to re-resection for incidental gallbladder cancer with overall survival: a multi-institution analysis from the US Extrahepatic Biliary Malignancy Consortium","volume":"152","author":"Ethun","year":"2017","journal-title":"JAMA Surg"},{"key":"2024092914180177200_bjs11035-bib-0036","doi-asserted-by":"crossref","first-page":"2821","DOI":"10.1007\/s00464-013-2819-5","article-title":"Prognosis of incidental gallbladder carcinoma is not influenced by the primary access technique: analysis of 837 incidental gallbladder carcinomas in the German Registry","volume":"27","author":"Goetze TO","year":"2013","journal-title":"Surg Endosc"},{"key":"2024092914180177200_bjs11035-bib-0037","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1007\/s11605-007-0309-6","article-title":"Incidence of finding residual disease for incidental gallbladder carcinoma: implications for re-resection","volume":"11","author":"Pawlik","year":"2007","journal-title":"J Gastrointest Surg"},{"key":"2024092914180177200_bjs11035-bib-0038","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.hpb.2016.05.016","article-title":"Rates and patterns of recurrence after curative intent resection for gallbladder cancer: a multi-institution analysis from the US Extra-hepatic Biliary Malignancy Consortium","volume":"18","author":"Margonis","year":"2016","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0039","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/jso.24283","article-title":"Assessing the impact of common bile duct resection in the surgical management of gallbladder cancer","volume":"114","author":"Gani","year":"2016","journal-title":"J Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0040","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1245\/s10434-016-5243-y","article-title":"Prognostic implications of lymph node status for patients with gallbladder cancer: a multi-institutional study","volume":"23","author":"Amini","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0041","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1245\/s10434-016-5637-x","article-title":"A novel pathology-based preoperative risk score to predict locoregional residual and distant disease and survival for incidental gallbladder cancer: a 10-institution study from the U.S. Extrahepatic Biliary Malignancy Consortium","volume":"24","author":"Ethun","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0042","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s00268-016-3691-y","article-title":"Defining the chance of statistical cure among patients with extrahepatic biliary tract cancer","volume":"41","author":"Spolverato","year":"2017","journal-title":"World J Surg"},{"key":"2024092914180177200_bjs11035-bib-0043","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jviscsurg.2013.03.006","article-title":"Is port-site resection necessary in the surgical management of gallbladder cancer?","volume":"150","author":"Fuks","year":"2013","journal-title":"J Visc Surg"},{"key":"2024092914180177200_bjs11035-bib-0044","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.hpb.2016.08.006","article-title":"Elevated NLR in gallbladder cancer and cholangiocarcinoma \u2013 making bad cancers even worse: results from the US Extrahepatic Biliary Malignancy Consortium","volume":"18","author":"Beal","year":"2016","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0045","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.1245\/s10434-014-3527-7","article-title":"Korean Pancreas Surgery Club. Surgical strategy for T1 gallbladder cancer: a nationwide multicenter survey in South Korea","volume":"21","author":"Lee","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0046","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.dld.2013.07.004","article-title":"Pathology report assessment of incidental gallbladder carcinoma diagnosed from cholecystectomy specimens: results of a French multicentre survey","volume":"45","author":"Chatelain","year":"2013","journal-title":"Dig Liver Dis"},{"key":"2024092914180177200_bjs11035-bib-0047","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1007\/s00464-011-2044-z","article-title":"The prognostic impact of positive lymph nodes in stages T1 to T3 incidental gallbladder carcinoma: results of the German Registry","volume":"26","author":"Goetze TO","year":"2012","journal-title":"Surg Endosc"},{"key":"2024092914180177200_bjs11035-bib-0048","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1007\/s00464-010-0914-4","article-title":"Adequate extent in radical re-resection of incidental gallbladder carcinoma: analysis of the German Registry","volume":"24","author":"Goetze","year":"2010","journal-title":"Surg Endosc"},{"key":"2024092914180177200_bjs11035-bib-0049","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1007\/s00464-008-9747-9","article-title":"Immediate re-resection of T1 incidental gallbladder carcinomas: a survival analysis of the German Registry","volume":"22","author":"Goetze","year":"2008","journal-title":"Surg Endosc"},{"key":"2024092914180177200_bjs11035-bib-0050","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/SLA.0b013e318154bf5d","article-title":"Benefits of reoperation of T2 and more advanced incidental gallbladder carcinoma: analysis of the German Registry","volume":"247","author":"Goetze","year":"2008","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0051","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.surg.2017.02.009","article-title":"Predictors of incidental gallbladder cancer in patients undergoing cholecystectomy for benign gallbladder disease: results from a population-based gallstone surgery registry","volume":"162","author":"Muszynska","year":"2017","journal-title":"Surgery"},{"key":"2024092914180177200_bjs11035-bib-0052","doi-asserted-by":"crossref","first-page":"131","DOI":"10.4174\/astr.2016.90.3.131","article-title":"Incidental gallbladder cancer after routine cholecystectomy: when should we suspect it preoperatively and what are predictors of patient survival?","volume":"90","author":"Ahn","year":"2016","journal-title":"Ann Surg Treat Res"},{"key":"2024092914180177200_bjs11035-bib-0053","doi-asserted-by":"crossref","first-page":"441","DOI":"10.4251\/wjgo.v6.i12.441","article-title":"Incidental gall bladder cancers: are they truly incidental?","volume":"6","author":"Rammohan","year":"2014","journal-title":"World J Gastrointest Oncol"},{"key":"2024092914180177200_bjs11035-bib-0054","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/SLA.0000000000000485","article-title":"Incidental gallbladder cancer at cholecystectomy: when should the surgeon be suspicious?","volume":"260","author":"Pitt","year":"2014","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0055","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.hbpd.2018.02.001","article-title":"Clues to predict incidental gallbladder cancer","volume":"17","author":"Goussous","year":"2018","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"2024092914180177200_bjs11035-bib-0056","article-title":"Surgically resected gall bladder: is histopathology needed for all?","volume":"2016","author":"Talreja","year":"2016","journal-title":"Surg Res Pract"},{"key":"2024092914180177200_bjs11035-bib-0057","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1245\/s10434-017-6025-x","article-title":"8th edition of the AJCC Cancer Staging Manual: pancreas and hepatobiliary cancers","volume":"25","author":"Chun","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0058","first-page":"303","volume-title":"AJCC Cancer Staging Manual","author":"Zhu","year":"2017"},{"key":"2024092914180177200_bjs11035-bib-0059","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/SLA.0000000000000728","article-title":"Tumor location is a strong predictor of tumor progression and survival in T2 gallbladder cancer: an international multicenter study","volume":"261","author":"Shindoh","year":"2015","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0060","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1245\/s10434-014-4300-7","article-title":"Surgical strategy for T2 gallbladder cancer according to tumor location","volume":"22","author":"Lee","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0061","article-title":"Management of high-grade dysplasia of the cystic duct after cholecystectomy","volume":"2017","author":"Moslim","year":"2017","journal-title":"BMJ Case Rep"},{"key":"2024092914180177200_bjs11035-bib-0062","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1111\/j.1477-2574.2011.00388.x","article-title":"High-grade dysplasia of the cystic duct margin in the absence of malignancy after cholecystectomy","volume":"13","author":"Bickenbach","year":"2011","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0063","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.hpb.2017.08.014","article-title":"Clinicopathological features and prognosis of advanced biliary carcinoma centered in the cystic duct","volume":"20","author":"Nakanishi","year":"2018","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0064","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1007\/s00268-009-0163-7","article-title":"Use of retrieval bags in incidental gallbladder cancer cases","volume":"33","author":"Goetze","year":"2009","journal-title":"World J Surg"},{"key":"2024092914180177200_bjs11035-bib-0065","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1007\/s00268-014-2864-9","article-title":"Surgical treatment of incidental gallbladder cancer discovered during or following laparoscopic cholecystectomy","volume":"39","author":"Tian","year":"2015","journal-title":"World J Surg"},{"key":"2024092914180177200_bjs11035-bib-0066","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1016\/j.jviscsurg.2011.02.005","article-title":"Incidentally-discovered gallbladder cancer: when, why and which reoperation?","volume":"148","author":"Isambert","year":"2011","journal-title":"J Visc Surg"},{"key":"2024092914180177200_bjs11035-bib-0067","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13017-018-0169-2","article-title":"Advanced gallbladder inflammation is a risk factor for gallbladder perforation in patients with acute cholecystitis","volume":"13","author":"Jansen","year":"2018","journal-title":"World J Emerg Surg"},{"key":"2024092914180177200_bjs11035-bib-0068","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/bjs.7265","article-title":"Preoperative inflammation is a prognostic factor for gallbladder carcinoma","volume":"98","author":"Han","year":"2011","journal-title":"Br J Surg"},{"key":"2024092914180177200_bjs11035-bib-0069","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1007\/s00268-011-1134-3","article-title":"Incidental gallbladder cancer by the AFC-GBC-2009 Study Group","volume":"35","author":"Fuks","year":"2011","journal-title":"World J Surg"},{"key":"2024092914180177200_bjs11035-bib-0070","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/hpb.12189","article-title":"Management of incidental and suspicious gallbladder cancer: focus on early referral to a tertiary centre","volume":"16","author":"Yip","year":"2014","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0071","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1007\/s11605-017-3537-4","article-title":"The effects of travel burden on outcomes after resection of extrahepatic biliary malignancies: results from the US Extrahepatic Biliary Consortium","volume":"21","author":"O'Connor","year":"2017","journal-title":"J Gastrointest Surg"},{"key":"2024092914180177200_bjs11035-bib-0072","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/13651820701867794","article-title":"Revision surgery for incidental gallbladder cancer: factors influencing operability and further evidence for T1b tumours","volume":"10","author":"Shukla","year":"2008","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0073","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/s00268-013-2266-4","article-title":"Patterns of failure and determinants of outcomes following radical re-resection for incidental gallbladder cancer","volume":"38","author":"Barreto","year":"2014","journal-title":"World J Surg"},{"key":"2024092914180177200_bjs11035-bib-0074","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1001\/jamasurg.2016.3643","article-title":"The timing of reoperation for incidental gallbladder cancer: sooner or later?","volume":"152","author":"Agopian","year":"2017","journal-title":"JAMA Surg"},{"key":"2024092914180177200_bjs11035-bib-0075","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1308\/003588414X14055925060073","article-title":"Implications of the index cholecystectomy and timing of referral for radical resection of advanced incidental gallbladder cancer","volume":"97","author":"Tsirlis","year":"2015","journal-title":"Ann R Coll Surg Engl"},{"key":"2024092914180177200_bjs11035-bib-0076","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/hpb.12032","article-title":"Incidental pT2\u2013T3 gallbladder cancer after a cholecystectomy: outcome of staging at 3 months prior to a radical resection","volume":"15","author":"Ausania","year":"2013","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0077","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.hpb.2016.11.006","article-title":"Does a second resection provide a survival benefit in patients diagnosed with incidental T1b\/T2 gallbladder cancer following cholecystectomy?","volume":"19","author":"Watson","year":"2017","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0078","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jhep.2006.03.009","article-title":"Impact of integrated positron emission tomography and computed tomography on staging and management of gallbladder cancer and cholangiocarcinoma","volume":"45","author":"Petrowsky","year":"2006","journal-title":"J Hepatol"},{"key":"2024092914180177200_bjs11035-bib-0079","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1477-2574.2008.00009.x","article-title":"The current role of PET\u2013CT in the characterization of hepatobiliary malignancies","volume":"11","author":"Garcea","year":"2009","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0080","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.cpet.2015.03.001","article-title":"FDG PET\/CT in pancreatic and hepatobiliary carcinomas: value to patient management and patient outcomes","volume":"10","author":"Parikh","year":"2015","journal-title":"PET Clin"},{"key":"2024092914180177200_bjs11035-bib-0081","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/jso.24198","article-title":"Role of PET CT scan in redefining treatment of incidental gall bladder carcinoma","volume":"113","author":"Goel","year":"2016","journal-title":"J Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0082","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1477-2574.2009.00104.x","article-title":"The role of PET\u2013CT in patients with incidental gallbladder cancer","volume":"11","author":"Butte","year":"2009","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0083","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1080\/13651820802286910","article-title":"Does PET\u2013CT scan have a role prior to radical re-resection for incidental gallbladder cancer?","volume":"10","author":"Shukla","year":"2008","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0084","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1111\/hpb.12282","article-title":"Impact of pre-operative positron emission tomography in gallbladder cancer","volume":"16","author":"Leung","year":"2014","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0085","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/jso.23476","article-title":"Ability of FDG-PET\/CT in the detection of gallbladder cancer","volume":"109","author":"Ramos-Font","year":"2014","journal-title":"J Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0086","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/SLA.0b013e318271497e","article-title":"The role of staging laparoscopy in primary gall bladder cancer \u2013 an analysis of 409 patients: a prospective study to evaluate the role of staging laparoscopy in the management of gallbladder cancer","volume":"258","author":"Agarwal","year":"2013","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0087","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1477-2574.2011.00325.x","article-title":"The role of laparoscopic staging in patients with incidental gallbladder cancer","volume":"13","author":"Butte","year":"2011","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0088","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/01.sla.0000154119.55201.e9","article-title":"Gallbladder cancer: what is an aggressive approach?","volume":"241","author":"Pitt","year":"2005","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0089","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1080\/00365521.2017.1284895","article-title":"Surgical treatment for gallbladder cancer \u2013 a systematic literature review","volume":"52","author":"Sternby Eilard","year":"2017","journal-title":"Scand J Gastroenterol"},{"key":"2024092914180177200_bjs11035-bib-0090","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1097\/SLA.0b013e3181675842","article-title":"What is an adequate extent of resection for T1 gallbladder cancers?","volume":"247","author":"You","year":"2008","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0091","doi-asserted-by":"crossref","first-page":"142","DOI":"10.14701\/kjhbps.2012.16.4.142","article-title":"Extent of resection for T2 N0 gallbladder carcinoma regarding concurrent extrahepatic bile duct resection","volume":"16","author":"Gwark","year":"2012","journal-title":"Korean J Hepatobiliary Pancreat Surg"},{"key":"2024092914180177200_bjs11035-bib-0092","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/SLA.0b013e31822238d8","article-title":"Accurate staging for gallbladder cancer: implications for surgical therapy and pathological assessment","volume":"254","author":"Ito","year":"2011","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0093","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1245\/s10434-008-0189-3","article-title":"Analysis of the extent of resection for adenocarcinoma of the gallbladder","volume":"16","author":"D'Angelica","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0094","article-title":"Survey results of the expert meeting on laparoscopic surgery for gallbladder cancer and a review of relevant literature","author":"Yoon","year":"2018","journal-title":"Dig Surg"},{"key":"2024092914180177200_bjs11035-bib-0095","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.hpb.2017.10.015","article-title":"Open versus laparoscopic portal lymphadenectomy in gallbladder cancer: is there a difference in lymph node yield?","volume":"20","author":"Ong","year":"2018","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0096","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000003675","article-title":"Impact of type of surgery on survival outcome in patients with early gallbladder cancer in the era of minimally invasive surgery: oncologic safety of laparoscopic surgery","volume":"95","author":"Jang","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"2024092914180177200_bjs11035-bib-0097","doi-asserted-by":"crossref","first-page":"124","DOI":"10.4103\/jmas.JMAS_181_16","article-title":"The technique of laparoscopic hepatic bisegmentectomy with regional lymphadenectomy for gallbladder cancer","volume":"14","author":"Nag","year":"2018","journal-title":"J Minim Access Surg"},{"key":"2024092914180177200_bjs11035-bib-0098","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8570502","article-title":"Laparoscopic radical cholecystectomy for primary or incidental early gallbladder cancer: the new rules governing the treatment of gallbladder cancer","volume":"2017","author":"Piccolo","year":"2017","journal-title":"Gastroenterol Res Pract"},{"key":"2024092914180177200_bjs11035-bib-0099","doi-asserted-by":"crossref","first-page":"3600","DOI":"10.1007\/s00464-015-4116-y","article-title":"Novel strategy for laparoscopic treatment of pT2 gallbladder carcinoma","volume":"29","author":"Itano","year":"2015","journal-title":"Surg Endosc"},{"key":"2024092914180177200_bjs11035-bib-0100","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/hpb.12406","article-title":"Minimally invasive versus the conventional open surgical approach of a radical cholecystectomy for gallbladder cancer: a retrospective comparative study","volume":"17","author":"Agarwal","year":"2015","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0101","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/7684915","article-title":"Current role of minimally invasive radical cholecystectomy for gallbladder cancer","volume":"2016","author":"Zimmitti","year":"2016","journal-title":"Gastroenterol Res Pract"},{"key":"2024092914180177200_bjs11035-bib-0102","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s12029-014-9597-8","article-title":"Gallbladder cancer, treatment failure and relapses: the peritoneum in gallbladder cancer","volume":"45","author":"Maplanka","year":"2014","journal-title":"J Gastrointest Cancer"},{"key":"2024092914180177200_bjs11035-bib-0103","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1245\/s10434-011-1850-9","article-title":"Is port site resection necessary in the surgical management of gallbladder cancer?","volume":"19","author":"Maker","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0104","doi-asserted-by":"crossref","first-page":"42","DOI":"10.14701\/ahbps.2018.22.1.42","article-title":"Role of common bile duct resection in T2 and T3 gallbladder cancer patients","volume":"22","author":"Lim","year":"2018","journal-title":"Ann Hepatobiliary Pancreat Surg"},{"key":"2024092914180177200_bjs11035-bib-0105","doi-asserted-by":"crossref","first-page":"81","DOI":"10.14740\/jocmr2804w","article-title":"To resect or not to resect extrahepatic bile duct in gallbladder cancer?","volume":"9","author":"Gavriilidis","year":"2017","journal-title":"J Clin Med Res"},{"key":"2024092914180177200_bjs11035-bib-0106","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1007\/s00595-009-3960-6","article-title":"Should the extrahepatic bile duct be resected or preserved in R0 radical surgery for advanced gallbladder carcinoma? Results of a Japanese Society of Biliary Surgery Survey: a multicenter study","volume":"39","author":"Araida","year":"2009","journal-title":"Surg Today"},{"key":"2024092914180177200_bjs11035-bib-0107","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/bjs.10415","article-title":"Prognostic value of carbohydrate antigen 19-9 in patients undergoing resection of biliary tract cancer","volume":"104","author":"Yamashita","year":"2017","journal-title":"Br J Surg"},{"key":"2024092914180177200_bjs11035-bib-0108","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s12029-016-9914-5","article-title":"Does CA 19-9 have prognostic relevance in gallbladder carcinoma (GBC)?","volume":"49","author":"Agrawal","year":"2018","journal-title":"J Gastrointest Cancer"},{"key":"2024092914180177200_bjs11035-bib-0109","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1477-2574.2009.00149.x","article-title":"Elevated CA 19-9 portends poor prognosis in patients undergoing resection of biliary malignancies","volume":"12","author":"Hatzaras","year":"2010","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0110","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.hpb.2017.06.011","article-title":"Elevation of CA19-9 and CEA is associated with a poor prognosis in patients with resectable gallbladder carcinoma","volume":"19","author":"Wen","year":"2017","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0111","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.21873\/anticanres.11544","article-title":"Evaluation of tumor markers and their impact on prognosis in gallbladder, bile duct and cholangiocellular carcinomas \u2013 a pilot study","volume":"37","author":"Liska","year":"2017","journal-title":"Anticancer Res"},{"key":"2024092914180177200_bjs11035-bib-0112","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s12029-011-9288-7","article-title":"Evaluation of CA 242 as a tumor marker in gallbladder cancer","volume":"43","author":"Rana","year":"2012","journal-title":"J Gastrointest Cancer"},{"key":"2024092914180177200_bjs11035-bib-0113","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/ans.14300","article-title":"Prognostic significance of pre-operative inflammatory markers in resected gallbladder cancer: a systematic review","volume":"88","author":"Saqib","year":"2018","journal-title":"ANZ J Surg"},{"key":"2024092914180177200_bjs11035-bib-0114","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/jso.23813","article-title":"Lymph node status after resection for gallbladder adenocarcinoma: prognostic implications of different nodal staging\/scoring systems","volume":"111","author":"Amini","year":"2015","journal-title":"J Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0115","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1007\/s10620-018-5103-7","article-title":"Establishment of a gallbladder cancer-specific survival model to predict prognosis in non-metastatic gallbladder cancer patients after surgical resection","volume":"63","author":"Zhang","year":"2018","journal-title":"Dig Dis Sci"},{"key":"2024092914180177200_bjs11035-bib-0116","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1245\/s10434-018-6444-3","article-title":"Efficacy of the gallbladder cancer predictive risk score based on pathological findings: a propensity score-matched analysis","volume":"25","author":"Mochizuki","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0117","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/SLA.0000000000002385","article-title":"Surgical management of gallbladder cancer: simple versus extended cholecystectomy and the role of adjuvant therapy","volume":"266","author":"Kasumova","year":"2017","journal-title":"Ann Surg"},{"key":"2024092914180177200_bjs11035-bib-0118","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijsu.2018.02.052","article-title":"Adjuvant systemic therapy after resection of node positive gallbladder cancer: time for a well-designed trial? (Results of a US-national retrospective cohort study)","volume":"52","author":"Bergquist","year":"2018","journal-title":"Int J Surg"},{"key":"2024092914180177200_bjs11035-bib-0119","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.semradonc.2014.01.001","article-title":"Defining the role of adjuvant therapy: cholangiocarcinoma and gall bladder cancer","volume":"24","author":"Williams","year":"2014","journal-title":"Semin Radiat Oncol"},{"key":"2024092914180177200_bjs11035-bib-0120","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.surg.2013.06.001","article-title":"Impact of adjuvant external beam radiotherapy on survival in surgically resected gallbladder adenocarcinoma: a propensity score-matched Surveillance, Epidemiology, and End Results analysis","volume":"155","author":"Hyder","year":"2014","journal-title":"Surgery"},{"key":"2024092914180177200_bjs11035-bib-0121","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJMoa0908721","article-title":"Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer","volume":"362","author":"Valle","year":"2010","journal-title":"N Engl J Med"},{"key":"2024092914180177200_bjs11035-bib-0122","article-title":"Adjuvant therapy for resected gallbladder cancer: analysis of the National Cancer Data Base","volume":"109","author":"Mantripragada","year":"2016","journal-title":"J Natl Cancer Inst"},{"key":"2024092914180177200_bjs11035-bib-0123","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/djw324","article-title":"Limited use of adjuvant therapy in patients with resected gallbladder cancer despite a strong association with survival","volume":"109","author":"Mitin","year":"2017","journal-title":"J Natl Cancer Inst"},{"key":"2024092914180177200_bjs11035-bib-0124","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/cncr.30968","article-title":"The role of surgery and adjuvant therapy in lymph node-positive cancers of the gallbladder and intrahepatic bile ducts","volume":"124","author":"Tran Cao","year":"2018","journal-title":"Cancer"},{"key":"2024092914180177200_bjs11035-bib-0125","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.1477-2574.2012.00559.x","article-title":"A 21-year analysis of stage I gallbladder carcinoma: is cholecystectomy alone adequate?","volume":"15","author":"Hari","year":"2013","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0126","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.hpb.2018.03.008","article-title":"Outcome of neoadjuvant chemotherapy in \u2018locally advanced\/borderline resectable\u2019 gallbladder cancer: the need to define indications","volume":"20","author":"Chaudhari","year":"2018","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0127","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.1245\/s10434-016-5197-0","article-title":"Neoadjuvant chemoradiation followed by surgery for locally advanced gallbladder cancers: a new paradigm","volume":"23","author":"Engineer","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"2024092914180177200_bjs11035-bib-0128","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1200\/JCO.2017.35.4_suppl.225","article-title":"Gemox versus surveillance following surgery of localized biliary tract cancer: results of the PRODIGE 12-ACCORD 18 (UNICANCER GI) phase III trial","volume":"35","author":"Edeline","year":"2017","journal-title":"J Clin Oncol"},{"key":"2024092914180177200_bjs11035-bib-0129","doi-asserted-by":"crossref","first-page":"OF1","DOI":"10.1158\/2159-8290.CD-NB2017-079","article-title":"Capecitabine extends survival for biliary tract cancer","volume":"7","year":"2017","journal-title":"Cancer Discov"},{"key":"2024092914180177200_bjs11035-bib-0130","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1186\/s12885-015-1498-0","article-title":"Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) \u2013 a randomized, multidisciplinary, multinational phase III trial","volume":"15","author":"Stein","year":"2015","journal-title":"BMC Cancer"},{"key":"2024092914180177200_bjs11035-bib-0131","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/S0140-6736(13)61455-5","article-title":"Strategies to improve clinical research in surgery through international collaboration","volume":"382","author":"S\u00f8reide","year":"2013","journal-title":"Lancet"},{"key":"2024092914180177200_bjs11035-bib-0132","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.hpb.2018.03.006","article-title":"Research gaps and unanswered questions in gallbladder cancer","volume":"20","author":"S\u00f8reide","year":"2018","journal-title":"HPB (Oxford)"},{"key":"2024092914180177200_bjs11035-bib-0133","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1158\/2159-8290.CD-17-0245","article-title":"New horizons for precision medicine in biliary tract cancers","volume":"7","author":"Valle","year":"2017","journal-title":"Cancer Discov"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.11035","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/106\/1\/32\/59433351\/bjs11035.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/106\/1\/32\/59433351\/bjs11035.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T14:18:31Z","timestamp":1727619511000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/106\/1\/32\/6092772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,1]]},"references-count":133,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,1,1]]},"published-print":{"date-parts":[[2019,1,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.11035","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,1]]},"published":{"date-parts":[[2019,1,1]]}}}