{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T15:12:44Z","timestamp":1788361964572,"version":"build-2803163510"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Incidental gallbladder cancer is a rare event, and its prognosis is largely affected by the tumour stage and treatment. The aim of this study was to analyse the management, treatment and survival of patients with incidental gallbladder cancer in a national cohort over a decade.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients were identified through the Swedish Registry of Gallstone Surgery (GallRiks). Data were cross-linked to the national registry for liver surgery (SweLiv) and the Cancer Registry. Medical records were collected if registry data were missing. Survival was measured as disease-specific survival. The study was divided into two intervals (2007\u20132011 and 2012\u20132016) to evaluate changes over time.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 249 patients were identified with incidental gallbladder cancer, of whom 92 (36\u00b79 per cent) underwent re-resection with curative intent. For patients with pT2 and pT3 disease, median disease-specific survival improved after re-resection (12\u00b74 versus 44\u00b71 months for pT2, and 9\u00b77 versus 23\u00b70 months for pT3). Residual disease was present in 53 per cent of patients with pT2 tumours who underwent re-resection; these patients had a median disease-specific survival of 32\u00b72 months, whereas the median was not reached in patients without residual disease. Median survival increased by 11 months for all patients between the early and late periods (P\u00a0=\u00a00\u00b7030).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Re-resection of pT2 and pT3 incidental gallbladder cancer was associated with improved survival, but survival was impaired when residual disease was present. A higher re-resection rate and more R0 resections in the later time period may have been associated with improved survival.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.11205","type":"journal-article","created":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T10:23:37Z","timestamp":1561976617000},"page":"1216-1227","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Management of incidental gallbladder cancer in a national cohort"],"prefix":"10.1093","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1927-2482","authenticated-orcid":false,"given":"L","family":"Lundgren","sequence":"first","affiliation":[{"name":"Department of Surgery, County Council of \u00d6sterg\u00f6tland and Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Link\u00f6ping University , Link\u00f6ping, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Muszynska","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sk\u00e5ne University Hospital and Department of Clinical Sciences, Lund University , Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Ros","sequence":"additional","affiliation":[{"name":"J\u00f6nk\u00f6ping Academy for Improvement of Health and Welfare, J\u00f6nk\u00f6ping University , J\u00f6nk\u00f6ping, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Persson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Ryhov Hospital , J\u00f6nk\u00f6ping, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0054-664X","authenticated-orcid":false,"given":"O","family":"Gimm","sequence":"additional","affiliation":[{"name":"Department of Surgery, County Council of \u00d6sterg\u00f6tland and Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Link\u00f6ping University , Link\u00f6ping, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5591-0659","authenticated-orcid":false,"given":"B","family":"Andersson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sk\u00e5ne University Hospital and Department of Clinical Sciences, Lund University , Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8078-9528","authenticated-orcid":false,"given":"P","family":"Sandstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Surgery, County Council of \u00d6sterg\u00f6tland and Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Link\u00f6ping University , Link\u00f6ping, 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