{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:22:52Z","timestamp":1792174972101,"version":"4.4.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Surgery for catecholamine-producing tumours can be complicated by intraoperative and postoperative haemodynamic instability. Several perioperative management strategies have emerged but none has been evaluated in randomized trials. To assess this issue, contemporary perioperative management and outcome data from 21 centres were collected.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Twenty-one centres contributed outcome data from patients who had surgery for phaeochromocytoma and paraganglioma between 2000 and 2017. The data included the number of patients with and without \u03b1-receptor blockade, surgical and anaesthetic techniques, complications and perioperative mortality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Across all centres, data were reported on 1860 patients with phaeochromocytoma or paraganglioma, of whom 343 underwent surgery without \u03b1-receptor blockade. The majority of operations (78\u00b79 per cent) were performed using minimally invasive techniques, including 16\u00b71 per cent adrenal cortex-sparing procedures. The cardiovascular complication rate was 5\u00b70 per cent overall: 5\u00b79 per cent (90 of 1517) in patients with preoperative \u03b1-receptor blockade and 0\u00b79 per cent (3 of 343) among patients without \u03b1-receptor blockade. The mortality rate was 0\u00b75 per cent overall (9 of 1860): 0\u00b75 per cent (8 of 517) in pretreated and 0\u00b73 per cent (1 of 343) in non-pretreated patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>There is substantial variability in the perioperative management of catecholamine-producing tumours, yet the overall complication rate is low. Further studies are needed to better define the optimal management approach, and reappraisal of international perioperative guidelines appears desirable.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.11378","type":"journal-article","created":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T01:14:40Z","timestamp":1578273280000},"page":"e170-e178","source":"Crossref","is-referenced-by-count":85,"title":["International multicentre review of perioperative management and outcome for catecholamine-producing tumours"],"prefix":"10.1093","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7542-5850","authenticated-orcid":false,"given":"H","family":"Groeben","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Critical Care Medicine and Pain Therapy , Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M K","family":"Walz","sequence":"additional","affiliation":[{"name":"Department of Minimally and General Surgery, Kliniken Essen-Mitte , Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B J","family":"Nottebaum","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Critical Care Medicine and Pain Therapy , Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P F","family":"Alesina","sequence":"additional","affiliation":[{"name":"Department of Minimally and General Surgery, Kliniken Essen-Mitte , Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Greenwald","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Columbia University , New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Schumann","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Tufts Medical Center , Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M 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